Q8QFV0

PR
Gene name
KCNT1 (SLACK)
Protein name
Potassium channel subfamily T member 1
Names
Sequence like a calcium-activated potassium channel subunit
Species
Gallus gallus (Chicken)
KEGG Pathway
gga:395248
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

596-703 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

6 structures for Q8QFV0

Entry ID Method Resolution Chain Position Source
5A6E EM 450 A PDB
5A6F EM 420 A PDB
5A6G EM 450 A B 244-337 PDB
5U70 EM 370 A A 1-1201 PDB
5U76 EM 420 A A 1-1201 PDB
AF-Q8QFV0-F1 Predicted AlphaFoldDB

No variants for Q8QFV0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8QFV0

No associated diseases with Q8QFV0

2 regional properties for Q8QFV0

Type Name Position InterPro Accession
domain Calcium-activated potassium channel BK, alpha subunit 483 - 577 IPR003929
domain Potassium channel domain 258 - 325 IPR013099

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
intracellular sodium activated potassium channel activity Enables the transmembrane transfer of potassium by a channel that opens in response to stimulus by a sodium ion or ions. Transport by a channel involves facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism. Sodium activated potassium channels have distinctive properties, including a large single channel conductance, subconductance states, and a block of single channel currents at positive potentials, similar to inward rectification.
outward rectifier potassium channel activity Enables the transmembrane transfer of a potassium ion by an outwardly-rectifying voltage-gated channel. An outwardly rectifying current-voltage relation is one where at any given driving force the outward flow of K+ ions exceeds the inward flow for the opposite driving force.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MARAKLKNSP SESNSHVKTV PPATTEDVRG VSPLLPARRM GSLGSDVGQR PHAEDFSMDS
70 80 90 100 110 120
SFSQVQVEFY VNENTFKERL KLFFIKNQRS SLRIRLFNFS LKLLTCLLYI VRVLLDNPEE
130 140 150 160 170 180
GIGCWECEKQ NYTLFNQSTK INWSHIFWVD RKLPLWAVQV SIALISFLET MLLIYLSYKG
190 200 210 220 230 240
NIWEQIFRIS FILEMINTVP FIITIFWPPL RNLFIPVFLN CWLAKYALEN MINDLHRAIQ
250 260 270 280 290 300
RTQSAMFNQV LILICTLLCL VFTGTCGIQH LERAGEKLSL FKSFYFCIVT FSTVGYGDVT
310 320 330 340 350 360
PKIWPSQLLV VIMICVALVV LPLQFEELVY LWMERQKSGG NYSRHRAQTE KHVVLCVSSL
370 380 390 400 410 420
KIDLLMDFLN EFYAHPRLQD YYVVILCPTE MDIQVRRVLQ IPLWSQRVIY LQGSALKDQD
430 440 450 460 470 480
LMRAKMDNGE ACFILSSRNE VDRTAADHQT ILRAWAVKDF APNCPLYVQI LKPENKFHVK
490 500 510 520 530 540
FADHVVCEEE CKYAMLALNC VCPATSTLIT LLVHTSRGQE GQESPEQWQR MYGRCSGNEV
550 560 570 580 590 600
YHIRMGDSKF FMEYEGKSFT YAAFHAHKKY GVCLIGIRRE ENKSILLNPG PRHIMAASDT
610 620 630 640 650 660
CFYINITKEE NSAFIFKQAE KQKKKGFAGR GTYDGPSRLP VHSIIASMGT VAMDLQNTEC
670 680 690 700 710 720
RPTNSSKLAL PAENGSGNRR PSIAPVLELA DTSSLLPCDL LSDQSEDEMT QSDEEGSAVV
730 740 750 760 770 780
EYVKGYPPNS PYIGSSPTLC HLLPEKAPFC CLRLDKGCKH NSFEDAKAYG FKNKLIIVSA
790 800 810 820 830 840
ETAGNGLYNF IVPLRAYYRS RKELNPIVLL LDNKPEHHFL EAICCFPMVY YMEGTIDNLD
850 860 870 880 890 900
SLLQCGIIYA DNLVVVDKES TMSAEEDYMA DAKTIVNVQT MFRLFPSLSI ITELTHPSNM
910 920 930 940 950 960
RFMQFRAKDS YSLALSKLEK KERENGSNLA FMFRLPFAAG RVFSISMLDT LLYQSFVKDY
970 980 990 1000 1010 1020
MITITRLLLG LDTTPGSGYL CAMKITEDDL WIRTYGRLFQ KLCSSSAEIP IGIYRTESHM
1030 1040 1050 1060 1070 1080
FATSEPHDIR AQSQISINVE DCEDTKDVKE HWGIKTGHHR NSCSSDQSEH PLLRRKSMQW
1090 1100 1110 1120 1130 1140
ARRLSRKGNK HSGKTAEWIS QQRLSLYRRS ERQELSELVK NRMKHLGLPT TGYDEMNDHQ
1150 1160 1170 1180 1190 1200
NTLSYVLINP PPDTRLELND IVYLIRSDPL AHVANDGHSR KSSCSNKLGP CNPETRDETQ
L