Q8PXV8

PR
Gene name
mtd (MM_1108)
Protein name
F420-dependent methylenetetrahydromethanopterin dehydrogenase
Names
MTD, Coenzyme F420-dependent N5,N10-methylenetetrahydromethanopterin dehydrogenase
Species
Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia)
KEGG Pathway
mma:MM_1108
EC number
1.5.98.1: With other, known, acceptors
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

219-279 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8PXV8

Entry ID Method Resolution Chain Position Source
AF-Q8PXV8-F1 Predicted AlphaFoldDB

No variants for Q8PXV8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8PXV8

No associated diseases with Q8PXV8

No regional properties for Q8PXV8

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q8PXV8

Functions

Description
EC Number 1.5.98.1 With other, known, acceptors
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
ferredoxin hydrogenase activity Catalysis of the reaction: 2 reduced ferredoxin + 2 H+ = 2 oxidized ferredoxin + H2.
methylenetetrahydromethanopterin dehydrogenase activity Catalysis of the reaction: 5,10-methylenetetrahydromethanopterin + coenzyme F420 + 2 H(+) = 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + reduced coenzyme F420.

2 GO annotations of biological process

Name Definition
methanogenesis, from carbon dioxide The chemical reactions and pathways resulting in the formation of methane, a colorless, odorless, flammable gas with the formula CH4, from other compounds, including carbon dioxide (CO2).
one-carbon metabolic process The chemical reactions and pathways involving the transfer of one-carbon units in various oxidation states.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKKMVNIGFI KMGNLGMSQV INLIQDEIAA REGITVRVFG TGAKMAPADA ADTESFKQWN
70 80 90 100 110 120
ADFVVIISPN AAAPGPTAAR EIWKDVPCII VSDGPTKKEA REAFEQEGFG YIILPVDPLI
130 140 150 160 170 180
GAKREFLDSV EMASFNADAM KVLSICGVVR LIQEELDKVT EQVASGKSGK DLELPHIFAK
190 200 210 220 230 240
PEKCVEHAGF ANPYAKSKAL AALHMAEKVA QVNFPACFML KEIEQVCLTA AAGHEIMGAA
250 260 270
AQLANQAREI EKSNDTVSRM PHAKNGAVLK KVRLYEKPE