Q8PX31
Gene name |
surE |
Protein name |
5'-nucleotidase SurE |
Names |
Nucleoside 5'-monophosphate phosphohydrolase |
Species |
Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88) (Methanosarcina frisia) |
KEGG Pathway |
mma:MM_1391 |
EC number |
3.1.3.5: Phosphoric monoester hydrolases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8PX31
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8PX31-F1 | Predicted | AlphaFoldDB |
No variants for Q8PX31
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q8PX31 | |||||
No associated diseases with Q8PX31
7 regional properties for Q8PX31
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Dynamin stalk domain | 222 - 490 | IPR000375 |
| domain | Dynamin, GTPase domain | 1 - 301 | IPR001401 |
| domain | Dynamin GTPase effector | 515 - 608 | IPR003130 |
| conserved_site | Dynamin, GTPase region, conserved site | 61 - 70 | IPR019762 |
| domain | GTPase effector domain | 520 - 612 | IPR020850 |
| domain | Dynamin-type guanine nucleotide-binding (G) domain | 32 - 301 | IPR030381 |
| domain | Dynamin, N-terminal | 38 - 213 | IPR045063 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.1.3.5 | Phosphoric monoester hydrolases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| metal ion binding | Binding to a metal ion. |
| nucleotide binding | Binding to a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose. |
| XMP 5'-nucleosidase activity | Catalysis of the reaction: 5'XMP + H20 = phosphate + xanthosine. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGKLMVPKIL | VTNDDGVYST | GLKAAFDSVS | DLGEVTISAP | AVQQSGVGRS | ISIFEPLRIT |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KTDVGGIPAY | AVGGTPTDSV | ILGVFTILKA | MPDLVLSGFN | IGENISTDTI | TTSGTIGGAL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| EAASYGVPAI | AASMQVLDEG | QKFDDPRDYQ | RERFEAGIKV | VNRIARNVLK | RGMPENVDLL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| NINIPFHAEE | DTPIEITRLA | RKIFKTDVEE | RRDPRGRPYY | WIAGDLIREE | EEGTDVHAIM |
| 250 | 260 | ||||
| QKGHVSITPI | SLDSTARIDF | SEIERYL |