Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q8PQE0

Entry ID Method Resolution Chain Position Source
AF-Q8PQE0-F1 Predicted AlphaFoldDB

No variants for Q8PQE0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8PQE0

No associated diseases with Q8PQE0

1 regional properties for Q8PQE0

Type Name Position InterPro Accession
domain Alpha/beta hydrolase fold-1 12 - 244 IPR000073

Functions

Description
EC Number 3.1.1.85 Carboxylic ester hydrolases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
carboxylic ester hydrolase activity Catalysis of the hydrolysis of a carboxylic ester bond.

1 GO annotations of biological process

Name Definition
biotin biosynthetic process The chemical reactions and pathways resulting in the formation of biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MHIDVIGHGP ALVLLHGWAL HGGVFAPLVE RLAPHYQLHL VDLPGHGFSR DDSTPLALPY
70 80 90 100 110 120
VVAEIAAATP PAVWLGWSLG GLFALHAAAT LPQVRGLAMI AATPRFVRGS DWPSAVQREV
130 140 150 160 170 180
FVQFGVELSR DYRGTLERFL ALDTLGSAHA RSELRSLRET LTARGEPAPE ALQQGLTLLE
190 200 210 220 230 240
RTDLRRTVPQ LARPSLWIAG QRDRLVPAAG MHAAAALSPH AQALTIAGGG HAPFLGHADQ
250
VSEALQRFVA SVP