Q8PPT1

PR
Gene name
treA
Protein name
Periplasmic trehalase
Names
Alpha,alpha-trehalase, Alpha,alpha-trehalose glucohydrolase
Species
Xanthomonas axonopodis pv citri (strain 306)
KEGG Pathway
xac:XAC0604
EC number
3.2.1.28: Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-83 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8PPT1

Entry ID Method Resolution Chain Position Source
AF-Q8PPT1-F1 Predicted AlphaFoldDB

No variants for Q8PPT1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8PPT1

No associated diseases with Q8PPT1

2 regional properties for Q8PPT1

Type Name Position InterPro Accession
conserved_site Glycoside hydrolase, family 37, conserved site 166 - 179 IPR018232-1
conserved_site Glycoside hydrolase, family 37, conserved site 461 - 470 IPR018232-2

Functions

Description
EC Number 3.2.1.28 Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds
Subcellular Localization
  • Periplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
periplasmic space The region between the inner (cytoplasmic) and outer membrane (Gram-negative Bacteria) or cytoplasmic membrane and cell wall (Fungi and Gram-positive Bacteria).

1 GO annotations of molecular function

Name Definition
alpha,alpha-trehalase activity Catalysis of the reaction: alpha,alpha-trehalose + H2O = 2 D-glucose.

2 GO annotations of biological process

Name Definition
cellular hyperosmotic response Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell.
trehalose catabolic process The chemical reactions and pathways resulting in the breakdown of trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPYATARSGD VMSSAAPPCC TSLLGLSLSM FVAPGTLTAA PLDAPVVNAP APTPPTPDLA
70 80 90 100 110 120
YPELFQAVQR GELFDDQKHF VDFLPLRDPA LINADYLAQH DHPGFDLRKF VDANFEESPP
130 140 150 160 170 180
VQTDAIRQDT ALREHIDLLW PKLVRSQNHV PPHSSLLALP HPYVVPGGRF REVYYWDSYF
190 200 210 220 230 240
TMLGLVKSGE TTLSRQMLDN FAYLIDTYGH IPNGNRTYYL SRSQPPFFSY MVELQAGVEG
250 260 270 280 290 300
EAVYQRYLPQ LQKEYAYWMQ GSDDLQPGQA ARHVVRLADG SVLNRYWDER DTPRPEAWLH
310 320 330 340 350 360
DTRTAAEVTD RPAAEVYRDL RAGAESGWDY TSRWLADGQN LRTIRTTAIL PIDLNSLLYH
370 380 390 400 410 420
LERTLALACA QPGAECTRDY AALAQQRKQA IDAHLWNTAG YYADYDWQTR TLSNQVTAAA
430 440 450 460 470 480
LYPLFAGLAS DDHAKRTAST VRKTLLRPGG LATTAVKTGQ QWDEPNGWAP LQWVAVDGLR
490 500 510 520 530 540
RYGEDALART IGERFLAQVQ ALFAREHKLV EKYGLETDAA GGGGGEYALQ DGFGWTNGVT
550 560
LMLLNLYPGK DTKAAPAKRV RKPEAAAR