Q8P4D7

PR
Gene name
ung
Protein name
Uracil-DNA glycosylase
Names
UDG
Species
Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)
KEGG Pathway
xcc:XCC3772
EC number
3.2.2.27: Hydrolyzing N-glycosyl compounds
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

160-241 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8P4D7

Entry ID Method Resolution Chain Position Source
AF-Q8P4D7-F1 Predicted AlphaFoldDB

No variants for Q8P4D7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8P4D7

No associated diseases with Q8P4D7

3 regional properties for Q8P4D7

Type Name Position InterPro Accession
conserved_site 14-3-3 protein, conserved site 46 - 56 IPR023409-1
conserved_site 14-3-3 protein, conserved site 218 - 237 IPR023409-2
domain 14-3-3 domain 6 - 249 IPR023410

Functions

Description
EC Number 3.2.2.27 Hydrolyzing N-glycosyl compounds
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
uracil DNA N-glycosylase activity Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases in DNA that result from the deamination of cytosine or the misincorporation of dUTP opposite an adenine.

1 GO annotations of biological process

Name Definition
base-excision repair, AP site formation via deaminated base removal A base-excision repair, AP site formation process occurring via excision of a deaminated base.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTEGEGRIQL EPSWKARVGE WLLQPQMQEL SAFLRQRKAA NARVFPPGPQ IFAAFDATPF
70 80 90 100 110 120
EQVKVVVLGQ DPYHGEGQAH GLCFSVLPGV PVPPSLLNIY KEIQDDLGIP RPDHGYLMPW
130 140 150 160 170 180
ARQGVLLLNA VLTVEQGRAG AHQNKGWEGF TDHVVETLNR EREGLVFLLW GSYAQSKGKV
190 200 210 220 230 240
IDQARHRVFK APHPSPLSAH RGFLGCKHFS KTNEHLQRRG LSPIDWSLPS RAALDLSLAG
G