Q8P000
Gene name |
rny |
Protein name |
Ribonuclease Y |
Names |
RNase Y |
Species |
Streptococcus pyogenes serotype M18 (strain MGAS8232) |
KEGG Pathway |
spm:spyM18_1643 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8P000
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8P000-F1 | Predicted | AlphaFoldDB |
No variants for Q8P000
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q8P000 | |||||
No associated diseases with Q8P000
6 regional properties for Q8P000
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | HD/PDEase domain | 344 - 450 | IPR003607 |
| domain | K Homology domain | 220 - 287 | IPR004087 |
| domain | K Homology domain, type 1 | 224 - 281 | IPR004088 |
| domain | HD domain | 348 - 441 | IPR006674 |
| domain | HDIG domain | 344 - 421 | IPR006675 |
| domain | Ribonuclease Y, N-terminal | 2 - 217 | IPR022711 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| endoribonuclease activity | Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks. |
| RNA binding | Binding to an RNA molecule or a portion thereof. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| mRNA catabolic process | The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MVNIILLIVS | ALIGLILGYA | LISIRLKSAK | EAAELTLLNA | EQEAVDIRGK | AEVDAEHIKK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TAKRESKANR | KELLLEAKEE | ARKYREEIEQ | EFKSERQELK | QLETRLAERS | LTLDRKDENL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SSKEKVLDSK | EQSLTDKSKH | IDERQLQVEK | LEEEKKAELE | KVAAMTIAEA | REVILMETEN |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KLTHEIATRI | RDAERDIKDR | TVKTAKDLLA | QAMQRLAGEY | VTEQTITSVH | LPDDNMKGRI |
| 250 | 260 | 270 | 280 | 290 | 300 |
| IGREGRNIRT | LESLTGIDVI | IDDTPEVVIL | SGFDPIRREI | ARMTLESLIA | DGRIHPARIE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ELVEKNRLEM | DNRIREYGEA | AAYEIGAPNL | HPDLIKIMGR | LQFRTSFGQN | VLRHSVEVGK |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LAGILAGELG | ENVALARRAG | FLHDMGKAID | REVEGSHVEI | GMEFARKYKE | HPVVVNTIAS |
| 430 | 440 | 450 | 460 | 470 | 480 |
| HHGDVEPDSV | IAVLVAAADA | LSSARPGARN | ESMENYIKRL | RDLEEIATSF | DGVQNSFALQ |
| 490 | 500 | 510 | 520 | 530 | |
| AGREIRIMVQ | PEKISDDQVV | ILSHKVREKI | EHNLDYPGNI | KVTVIREMRA | VDYAK |