Q8NNJ7
Gene name |
cobS |
Protein name |
Adenosylcobinamide-GDP ribazoletransferase |
Names |
Cobalamin synthase, Cobalamin-5'-phosphate synthase |
Species |
Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) |
KEGG Pathway |
cgl:Cgl2201 |
EC number |
2.7.8.26: Transferases for other substituted phosphate groups |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8NNJ7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8NNJ7-F1 | Predicted | AlphaFoldDB |
No variants for Q8NNJ7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q8NNJ7 | |||||
No associated diseases with Q8NNJ7
No regional properties for Q8NNJ7
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q8NNJ7 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 2.7.8.26 | Transferases for other substituted phosphate groups |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| adenosylcobinamide-GDP ribazoletransferase activity | Catalysis of the reaction: adenosylcobinamide-GDP + alpha-ribazole = GMP + adenosylcobalamin. |
| cobalamin 5'-phosphate synthase activity | Catalysis of the reaction: adenosylcobinamide-GDP + alpha-ribazole-5'-phosphate = adenosylcobalamin-5'-phosphate + GMP. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| cobalamin biosynthetic process | The chemical reactions and pathways resulting in the formation of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSGKAGFTPE | DPEDSDNRHG | NPLFEGIFTA | LNWMTVLPVP | GASVFDRTTG | ARVMASLPFV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| GFVFGMFTAI | IMWAIGPISG | VIHVDGLLVA | VLIVAFWELL | NRFMHLDGLA | DVSDALGSYA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| APPRAREILA | DPRTGLFGLA | TAMLSVLLQV | AAVASLVDST | VWWMICFIPV | LGRIAGQVTA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LKNHNAFSPT | GFGALVIGTV | KFWWIALWLL | VTAALAFWCA | ELISPLSPLT | SVNTPFVAGP |
| 250 | 260 | 270 | 280 | 290 | 300 |
| FPAAINPAWL | GGWVAITAVV | ACVFAALFSR | RLSRSFGGLN | GDCIGACIHL | GASISAVMFA |
| VVANAMV |