Q8NKG9
Gene name |
SLD |
Protein name |
Delta 8-(E)-sphingolipid desaturase |
Names |
|
Species |
Lachancea kluyveri (strain ATCC 58438 / CBS 3082 / BCRC 21498 / NBRC 1685 / JCM 7257 / NCYC 543 / NRRL Y-12651) (Yeast) (Saccharomyces kluyveri) |
KEGG Pathway |
ag:BAB93117 |
EC number |
1.14.19.18: With oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8NKG9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8NKG9-F1 | Predicted | AlphaFoldDB |
No variants for Q8NKG9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q8NKG9 | |||||
No associated diseases with Q8NKG9
Functions
| Description | ||
|---|---|---|
| EC Number | 1.14.19.18 | With oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| metal ion binding | Binding to a metal ion. |
| oxidoreductase activity | Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| sphingolipid metabolic process | The chemical reactions and pathways involving sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid). |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MDNIISRGEI | EDRIARGQAI | VIYEGLVLNL | EKWIKFHPGG | DKAIHHMIGR | DATDEMKAYH |
| 70 | 80 | 90 | 100 | 110 | 120 |
| CDETVEIFRK | WRIGRIDQEW | ENFLPPIQGG | VFRFLNQQHD | STDLGLSNKW | IAPNTSDQFK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| FIKNEKHMCG | EPDVKIYPKI | PQGVIPSLNL | KEAYEKKVVT | DPATVADNYD | NELVRQDLET |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LPDLDPKTQE | WLSKEYNKMH | NEIIEAGLYQ | CNYFRYVKEL | TRIGLLFALS | YYLLYHRDQK |
| 250 | 260 | 270 | 280 | 290 | 300 |
| FWSAFSMGCA | WQQLVFIAHD | AGHISITHHY | QLDNIFGMII | ASWVGGLSLG | WWKRNHNVHH |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LITNDPIHDP | DIQHLPFFAV | STRLFDNIYS | TYYEKFLWFD | AFAKKVVPWQ | NYLYYPMLAF |
| 370 | 380 | 390 | 400 | 410 | 420 |
| GRFNLYRLSW | MHVLLGLGPR | RGKAGWFRYF | ELCGLIFFNY | WFFYLLVGCK | LQTGWDRFQY |
| 430 | 440 | 450 | 460 | 470 | 480 |
| IMVSHITTML | VHVQITLSHF | AMSTSDLGVG | EGFPMRQLRT | SMDVDCPRWL | DFLHGGLQFQ |
| 490 | 500 | 510 | 520 | 530 | 540 |
| VVHHLFPRLP | RHNLRAAQPY | VIEFCEKVGI | KYSIYGFSKG | NGVVLTKLQE | IAVQAKTMLE |
| 550 | 560 | ||||
| CASAMKKEAT | GEREADEKTY | RTKSIKNA |