AiPD: Autoinhibited Protein Database

Q8NHP6

Gene name	MOSPD2
Protein name	Motile sperm domain-containing protein 2
Names
Species	Homo sapiens (Human)
KEGG Pathway	hsa:158747
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

411-495 (Predicted disordered autoinhibitory region) PR

Target domain
Relief mechanism
Assay	cis-regPred

AID

411-495 (Predicted disordered autoinhibitory region)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Yeon JH et al. (2016) "Systems-wide Identification of cis-Regulatory Elements in Proteins", Cell Systems, 2, 89-100

Autoinhibited structure

Activated structure

4 structures for Q8NHP6

Entry ID	Method	Resolution	Chain	Position	Source
6TQS	X-ray	225 A	A/B/C/D/E/F	282-490	PDB
6TQT	X-ray	150 A	A	282-490	PDB
6TQU	X-ray	240 A	A/B	315-445	PDB
AF-Q8NHP6-F1	Predicted				AlphaFoldDB

213 variants for Q8NHP6

Variant ID(s)	Position	Change	Description	Diseaes Association	Provenance
TCGA novel	1	M>?	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	3	E>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA412445528 rs1158167728	3	E>Q		No	ClinGen gnomAD
CA412445549 rs1471203802	4	N>Y		No	ClinGen gnomAD
rs780598216 CA10353270	5	H>Q		No	ClinGen ExAC TOPMed gnomAD
rs1424800473 CA412445564	6	A>S		No	ClinGen gnomAD
CA412445572 rs1468399379	7	Q>R		No	ClinGen gnomAD
rs1221540390 CA412445580	8	N>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
rs747306358 CA10353271	11	K>N		No	ClinGen ExAC gnomAD
CA412445598 rs1174053875	11	K>Q		No	ClinGen gnomAD
rs1322759303 CA412445603	11	K>R		No	ClinGen TOPMed
rs1288703409 CA412445622	14	S>C		No	ClinGen TOPMed
CA10353272 rs769255922	22	A>T		No	ClinGen ExAC gnomAD
CA412445678 rs1328105316	23	E>K		No	ClinGen gnomAD
rs747760686 CA10353274	26	T>P		No	ClinGen ExAC gnomAD
rs755293601 CA10353289	28	K>E		No	ClinGen ExAC gnomAD
CA10353291 rs375563130	34	A>G		No	ClinGen ESP ExAC gnomAD
rs375563130 CA10353292	34	A>V		No	ClinGen ESP ExAC gnomAD
CA10353293 COSM1116741 rs145214899	35	R>C	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD
rs748763207 CA10353294	35	R>H	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA10353295 rs147627753	42	Q>R		No	ClinGen ESP ExAC TOPMed gnomAD
CA327065636 rs3174450	45	N>K		No	ClinGen Ensembl
rs1292225834 CA412435321	45	N>S		No	ClinGen TOPMed
rs1436222825 CA412435333	47	V>I		No	ClinGen TOPMed
CA412435344 rs1318305263	48	E>G		No	ClinGen gnomAD
CA412435351 rs1355537127	49	S>T		No	ClinGen TOPMed
CA412435377 rs1436651521	53	W>G		No	ClinGen Ensembl
CA412435387 rs1477616051	54	R>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA10353296 rs773858437	55	H>Y		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	62	L>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA412435454 rs1428106435	63	K>N		No	ClinGen TOPMed
CA327065637 rs907801894	64	M>I		No	ClinGen gnomAD
TCGA novel	65	L>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA10353298 rs771780826	66	D>N	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs775308720 CA10353299	67	E>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA327065638 rs142229431	75	I>M		No	ClinGen ESP
TCGA novel	75	I>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs371878524 CA10353301	76	S>F		No	ClinGen ESP ExAC TOPMed gnomAD
rs756650603 CA10353309	81	N>S		No	ClinGen ExAC TOPMed gnomAD
rs146163894 CA327065794	91	E>K		No	ClinGen ESP TOPMed gnomAD
rs1396043047 CA412435742	92	I>M		No	ClinGen TOPMed
CA412435770 rs1442700764	95	I>N		No	ClinGen TOPMed gnomAD
rs770339586 CA10353312	97	L>F		No	ClinGen ExAC TOPMed gnomAD
CA10353313 rs746588950	98	H>R		No	ClinGen ExAC TOPMed gnomAD
rs1383182994 CA412435862	103	E>A		No	ClinGen gnomAD
CA327065796 rs371329982	106	K>N		No	ClinGen Ensembl
TCGA novel	107	L>M	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	109	W>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA10353326 rs753107625	111	R>G		No	ClinGen ExAC gnomAD
CA412436319 rs1176223996	113	K>E		No	ClinGen gnomAD
TCGA novel	117	K>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA327065899 rs930032726	122	I>L		No	ClinGen Ensembl
CA327065900 rs1056458554	122	I>T		No	ClinGen Ensembl
CA412436494 rs1337969791	125	K>T		No	ClinGen gnomAD
rs778315491 CA10353328	129	I>T		No	ClinGen ExAC TOPMed gnomAD
CA327065901 rs896668101	130	A>T		No	ClinGen Ensembl
rs908131981 CA327065902	130	A>V		No	ClinGen TOPMed gnomAD
rs1333522487 CA412436568	132	W>R		No	ClinGen TOPMed
CA10353329 rs754359723	136	Y>F		No	ClinGen ExAC TOPMed gnomAD
CA10353330 rs373192139	144	P>A		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA10353331 rs778320150	144	P>L		No	ClinGen ExAC gnomAD
CA412436694 rs1331575756	145	V>L		No	ClinGen gnomAD
CA10353332 rs745355830	154	T>S		No	ClinGen ExAC
rs1468508961 CA412436781	158	S>G		No	ClinGen TOPMed
CA412436787 rs1277502925	158	S>R		No	ClinGen gnomAD
rs767688089 CA10353343	165	R>C		No	ClinGen ExAC gnomAD
rs1263277769 CA412437033	165	R>H		No	ClinGen TOPMed
CA10353344 rs775680398	168	I>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs1281625900 CA412437117	172	K>N		No	ClinGen gnomAD
rs774292970 CA327066248	181	K>N		No	ClinGen TOPMed
CA10353361 rs769665676	183	V>L		No	ClinGen ExAC gnomAD
TCGA novel	184	I>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1018809258 CA327066249	185	F>S		No	ClinGen Ensembl
TCGA novel	186	D>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA10353362 rs184946599	187	M>T		No	ClinGen 1000Genomes ExAC TOPMed
TCGA novel	188	P>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA10353364 rs772139976	192	N>S		No	ClinGen ExAC gnomAD
rs1233375767 CA412437434	193	A>T		No	ClinGen TOPMed
rs1485103067 CA412438094	196	K>R		No	ClinGen gnomAD
CA10353371 rs765732670	201	W>C		No	ClinGen ExAC gnomAD
rs999972979 CA327066642	202	L>F		No	ClinGen Ensembl
rs758774781 CA10353373	214	S>R		No	ClinGen ExAC gnomAD
CA412438313 rs1602037662	216	N>D		No	ClinGen Ensembl
rs766009045 CA10353374	216	N>K		No	ClinGen ExAC gnomAD
TCGA novel	217	E>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	219	Q>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs754716748 CA10353376	220	D>A		No	ClinGen ExAC gnomAD
rs1343605272 CA412438400	223	S>I		No	ClinGen TOPMed gnomAD
rs1343605272 CA412438398	223	S>N		No	ClinGen TOPMed gnomAD
rs752489544 CA10353378	223	S>R		No	ClinGen ExAC gnomAD
CA327066660 rs143673501	226	Y>H		No	ClinGen ESP gnomAD
CA412438454 rs1258882715	228	P>L		No	ClinGen TOPMed
CA10353380 rs777360876	230	H>N		No	ClinGen ExAC gnomAD
CA10353381 rs746053684	232	G>S		No	ClinGen 1000Genomes ExAC gnomAD
rs370427075 CA327066662	234	T>N		No	ClinGen Ensembl
CA327066830 rs975603419	236	P>S		No	ClinGen Ensembl
TCGA novel	237	F>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs35164803 VAR_034109 CA10353393	240	S>N		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
TCGA novel	240	S>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA10353395 rs752396113	245	V>A		No	ClinGen ExAC TOPMed gnomAD
CA327066831 rs370959017	245	V>I		No	ClinGen ESP TOPMed
CA412438726 rs370959017	245	V>L		No	ClinGen ESP TOPMed
rs1275723913 CA412438805	251	T>S		No	ClinGen gnomAD
rs1569106135 CA412438882	258	P>R		No	ClinGen Ensembl
rs1370802848 CA412438885	259	I>V		No	ClinGen gnomAD
CA412438918 rs777657462	262	E>K		No	ClinGen ExAC gnomAD
CA10353397 rs777657462	262	E>Q		No	ClinGen ExAC gnomAD
TCGA novel	271	I>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs772728487 CA327066832	272	E>A		No	ClinGen Ensembl
rs1323315172 CA412439054	273	S>C		No	ClinGen TOPMed gnomAD
rs1323315172 CA412439053	273	S>G		No	ClinGen TOPMed gnomAD
TCGA novel	277	E>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1443465490 CA412439130	279	L>S		No	ClinGen gnomAD
CA412439135 rs1385341760	280	E>K		No	ClinGen TOPMed
rs757238717 CA10353399	287	Q>K		No	ClinGen ExAC gnomAD
rs377500177 CA412439236	288	T>I		No	ClinGen gnomAD
CA327066833 rs377500177	288	T>K		No	ClinGen gnomAD
rs778812199 CA10353400	289	P>R		No	ClinGen ExAC TOPMed gnomAD
rs1439661540 CA412439893 COSM1116744	298	E>K	Variant assessed as Somatic; 0.0 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated NCI-TCGA TOPMed gnomAD
CA10353414 rs760049672	299	S>P		No	ClinGen ExAC gnomAD
rs760049672 CA10353413	299	S>T		No	ClinGen ExAC gnomAD
rs1382386431 CA412439962	303	A>E		No	ClinGen TOPMed
rs752096955 CA10353415	303	A>T		No	ClinGen ExAC gnomAD
rs1602039826 CA412439995	305	E>D		No	ClinGen Ensembl
CA412440013 rs1373265166	307	E>K		No	ClinGen TOPMed gnomAD
TCGA novel	310	D>missing	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1478195809 CA412440079	311	S>L		No	ClinGen gnomAD
TCGA novel	313	V>G	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs905836720 CA327066867	315	A>S		No	ClinGen TOPMed
rs145104885 CA327066868	319	P>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs145104885 CA10353419	319	P>R		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs982032203 CA327066869	321	S>N		No	ClinGen Ensembl
CA10353421 rs368007476	322	V>L		No	ClinGen ESP ExAC gnomAD
TCGA novel	325	G>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs758285034 CA10353422	329	H>Y		No	ClinGen ExAC gnomAD
rs867674887 CA327066982	332	P>Q		No	ClinGen Ensembl
CA10353435 rs41297321	340	S>I		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA10353434 rs41297321	340	S>N		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs199908168 CA327066983	341	T>A		No	ClinGen Ensembl
CA10353437 rs765041573	344	G>R		No	ClinGen ExAC TOPMed gnomAD
rs1164665484 CA412440646	348	T>I		No	ClinGen gnomAD
CA10353438 rs750180336	351	V>L		No	ClinGen ExAC gnomAD
rs369620205 CA327067060	366	T>I		No	ClinGen ESP TOPMed
TCGA novel	378	N>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	381	C>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1172864310 CA412440981	382	D>G		No	ClinGen gnomAD
rs766405868 CA10353461	383	P>L		No	ClinGen ExAC gnomAD
CA412440989 rs766405868	383	P>R		No	ClinGen ExAC gnomAD
CA327067062 rs1050358567	384	G>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen Ensembl NCI-TCGA
rs1393417509 CA412440991	384	G>R		No	ClinGen TOPMed
CA412441104 rs1413654251	400	S>P		No	ClinGen gnomAD
CA327067078 rs968134247	401	A>V		No	ClinGen Ensembl
TCGA novel	403	D>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs373087009 CA10353471	404	R>C		No	ClinGen ESP ExAC gnomAD
CA412441134 rs1176124863	404	R>H		No	ClinGen gnomAD
rs769168126 CA10353472	407	I>V		No	ClinGen ExAC gnomAD
CA10353473 rs780722199	408	M>I		No	ClinGen ExAC
rs1468017402 CA412441177	410	A>T		No	ClinGen TOPMed gnomAD
rs747633106 CA10353474	412	M>I		No	ClinGen ExAC gnomAD
CA412441201 rs1287188596	412	M>V		No	ClinGen TOPMed
rs1395867508 CA412441210	413	E>K		No	ClinGen gnomAD
CA412441226 rs1389701540	415	S>A		No	ClinGen gnomAD
CA10353475 rs769492399	415	S>L		No	ClinGen ExAC gnomAD
CA412441224 rs1389701540	415	S>T		No	ClinGen gnomAD
rs772846336 CA10353476	416	S>C		No	ClinGen ExAC gnomAD
CA10353477 rs762599533	417	G>A		No	ClinGen ExAC gnomAD
rs762599533 CA412441238	417	G>V		No	ClinGen ExAC gnomAD
CA327067079 rs142203054	418	T>I		No	ClinGen ESP TOPMed gnomAD
CA10353478 rs764071636	420	P>S		No	ClinGen ExAC TOPMed gnomAD
CA412441277 rs1212160046	424	T>A		No	ClinGen gnomAD
CA327067080 rs935104308	424	T>I		No	ClinGen Ensembl
CA412441329 rs1256477922	431	P>A		No	ClinGen gnomAD
CA10353479 rs376188992	432	R>K		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA10353481 rs767527870	433	N>K		No	ClinGen ExAC gnomAD
rs759420459 CA10353480	433	N>S		No	ClinGen ExAC gnomAD
rs1472712274 CA412441368	436	M>I		No	ClinGen gnomAD
CA412441381 rs1199218234	438	H>R		No	ClinGen gnomAD
rs145446651 CA327067081	438	H>Y		No	ClinGen 1000Genomes TOPMed gnomAD
CA10353496 rs777872789	443	H>R		No	ClinGen ExAC TOPMed gnomAD
CA10353495 rs777203055	443	H>Y		No	ClinGen ExAC gnomAD
CA10353497 rs11797118	444	T>I		No	ClinGen ESP ExAC TOPMed gnomAD
rs759364943 CA10353499	449	K>T	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA412441476 rs1261685821	450	P>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs1192115262 CA412441475	450	P>S		No	ClinGen gnomAD
TCGA novel	453	L>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA412441502 rs772206668	454	T>K		No	ClinGen ExAC gnomAD
CA10353500 rs772206668	454	T>M	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
CA412441503 rs772206668	454	T>R		No	ClinGen ExAC gnomAD
CA412441525 CA327067229 rs979142049	457	D>E		No	ClinGen gnomAD
CA10353502 rs771081569	458	N>S		No	ClinGen ExAC TOPMed gnomAD
rs1287374803 CA412441611	469	D>G		No	ClinGen TOPMed
CA327067230 rs956150373	469	D>N	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs1356878782 CA412441620	470	I>M		No	ClinGen TOPMed
CA10353503 rs765430843	470	I>T		No	ClinGen ExAC TOPMed gnomAD
rs1569107911 CA412441661	475	S>C		No	ClinGen Ensembl
CA10353516 rs745450327	476	R>H		No	ClinGen ExAC TOPMed gnomAD
CA412441694 rs1434743046	480	S>C		No	ClinGen gnomAD
rs1344390933 COSM1743803 CA412441705	481	N>S	biliary_tract [Cosmic]	No	ClinGen cosmic curated TOPMed gnomAD
TCGA novel	482	R>M	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA327067287 rs906678814	490	R>C		No	ClinGen TOPMed
CA10353518 rs186948760	490	R>H		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs768684561 COSM3701811 CA10353520	492	I>V	liver [Cosmic]	No	ClinGen cosmic curated ExAC gnomAD
CA412441789 rs1281917140	493	W>R		No	ClinGen gnomAD
CA412441808 rs1380960859	494	F>L		No	ClinGen gnomAD
CA10353521 rs760339015	494	F>S		No	ClinGen 1000Genomes ExAC gnomAD
CA10353522 rs149352938	497	L>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs753032101 CA10353523	503	M>V		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	504	L>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA10353524 rs774637512	505	L>F		No	ClinGen ExAC gnomAD
rs759696962 CA10353525	511	S>C		No	ClinGen ExAC gnomAD
CA412442028 rs1208182877	511	S>P		No	ClinGen gnomAD
rs905695161 CA327067288	513	F>V		No	ClinGen Ensembl
rs1473128001 CA412442070	514	Y>N		No	ClinGen gnomAD

No associated diseases with Q8NHP6

5 regional properties for Q8NHP6

Type	Name	Position	InterPro Accession
conserved_site	MoaA/NifB/PqqE, iron-sulphur binding, conserved site	73 - 84	IPR000385
domain	Molybdopterin cofactor biosynthesis C (MoaC) domain	490 - 625	IPR002820
domain	Elp3/MiaA/NifB-like, radical SAM core domain	67 - 270	IPR006638
domain	Radical SAM	56 - 380	IPR007197
domain	Molybdenum cofactor biosynthesis protein A-like, twitch domain	239 - 373	IPR010505

Functions

		Description
EC Number
Subcellular Localization	Endoplasmic reticulum membrane ; Single-pass type IV membrane protein	Localization to contact sites involving the endoplasmic reticulum and several organelles is regulated by interaction with proteins containing FFAT motif (PubMed:29858488) Dynamically distributes between specific subdomains of the endoplasmic reticulum (ER): ER membranes in contact with lipid droplets (LDs) and the remainder of the ER (PubMed:35389430)
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

9 GO annotations of cellular component

Name	Definition
endomembrane system	A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.
endoplasmic reticulum	The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
endoplasmic reticulum membrane	The lipid bilayer surrounding the endoplasmic reticulum.
endoplasmic reticulum-endosome membrane contact site	A contact site between the endoplasmic reticulum membrane and the endosome membrane.
integral component of plasma membrane	The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
membrane	A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
organelle membrane contact site	A zone of apposition between the membranes of an organelle with another membrane, either another membrane of the same organelle, a membrane of another organelle, or the plasma membrane. Membrane contact sites (MCSs) are structured by bridging complexes. They are specialized for communication, including the efficient traffic of small molecules such as Ca2+ ions and lipids, as well as enzyme-substrate interactions.
plasma membrane	The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
specific granule membrane	The lipid bilayer surrounding a specific granule, a granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase.

No GO annotations of molecular function

Name	Definition
No GO annotations for molecular function

3 GO annotations of biological process

Name	Definition
chemotaxis	The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
positive regulation of monocyte chemotaxis	Any process that increases the frequency, rate, or extent of monocyte chemotaxis.
positive regulation of neutrophil chemotaxis	Any process that increases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.

No homologous proteins in AiPD

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
No homologous proteins

10	20	30	40	50	60
MAENHAQNKA	KLISETRRRF	EAEYVTDKSD	KYDARDVERL	QQDDNWVESY	LSWRHNIVDE
70	80	90	100	110	120
TLKMLDESFQ	WRKEISVNDL	NESSIPRWLL	EIGVIYLHGY	DKEGNKLFWI	RVKYHVKDQK
130	140	150	160	170	180
TILDKKKLIA	FWLERYAKRE	NGKPVTVMFD	LSETGINSID	MDFVRFIINC	FKVYYPKYLS
190	200	210	220	230	240
KIVIFDMPWL	MNAAFKIVKT	WLGPEAVSLL	KFTSKNEVQD	YVSVEYLPPH	MGGTDPFKYS
250	260	270	280	290	300
YPPLVDDDFQ	TPLCENGPIT	SEDETSSKED	IESDGKETLE	TISNEEQTPL	LKKINPTEST
310	320	330	340	350	360
SKAEENEKVD	SKVKAFKKPL	SVFKGPLLHI	SPAEELYFGS	TESGEKKTLI	VLTNVTKNIV
370	380	390	400	410	420
AFKVRTTAPE	KYRVKPSNSS	CDPGASVDIV	VSPHGGLTVS	AQDRFLIMAA	EMEQSSGTGP
430	440	450	460	470	480
AELTQFWKEV	PRNKVMEHRL	RCHTVESSKP	NTLTLKDNAF	NMSDKTSEDI	CLQLSRLLES
490	500	510
NRKLEDQVQR	CIWFQQLLLS	LTMLLLAFVT	SFFYLLYS