AiPD: Autoinhibited Protein Database

Q8N8M0

Gene name	NAT16 (C7orf52)
Protein name	Probable N-acetyltransferase 16
Names
Species	Homo sapiens (Human)
KEGG Pathway	hsa:375607
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-82 (Predicted disordered autoinhibitory region) PR

Target domain
Relief mechanism
Assay	cis-regPred

AID

1-82 (Predicted disordered autoinhibitory region)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Yeon JH et al. (2016) "Systems-wide Identification of cis-Regulatory Elements in Proteins", Cell Systems, 2, 89-100

Autoinhibited structure

Activated structure

1 structures for Q8N8M0

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q8N8M0-F1	Predicted				AlphaFoldDB

401 variants for Q8N8M0

Variant ID(s)	Position	Change	Description	Diseaes Association	Provenance
rs532463604 CA368649749	2	K>N		No	ClinGen ExAC TOPMed gnomAD
rs767752008 CA4406832	5	A>D	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA4406829 rs141768939	11	T>N		No	ClinGen ESP ExAC TOPMed gnomAD
rs1231213480 CA368649626	13	E>D		No	ClinGen TOPMed gnomAD
CA163370814 rs373678437	13	E>K		No	ClinGen ESP
CA368649608 rs1333807517	15	P>L		No	ClinGen gnomAD
rs773603616 CA4406827	16	K>R		No	ClinGen ExAC gnomAD
rs143939241 CA4406822	17	P>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA4406823 rs143939241	17	P>Q		No	ClinGen ESP ExAC TOPMed gnomAD
rs146332959 CA4406825	17	P>S		No	ClinGen 1000Genomes ESP ExAC gnomAD
CA4406824 rs146332959	17	P>T		No	ClinGen 1000Genomes ESP ExAC gnomAD
rs1398168711 CA368649571	19	K>E		No	ClinGen gnomAD
rs555118087 CA4406820	21	T>A		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs199889473 CA4406819	22	A>D		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs199889473 CA4406818	22	A>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1584222266 CA368649526	23	R>Q		No	ClinGen Ensembl
rs755819266 CA4406817	24	D>N		No	ClinGen ExAC TOPMed gnomAD
rs752553136 CA4406816	25	A>S		No	ClinGen ExAC TOPMed gnomAD
rs867086471 CA163370802	25	A>V		No	ClinGen Ensembl
CA4406814 rs767662024	27	P>A		No	ClinGen ExAC TOPMed gnomAD
rs566267507 CA4406813	28	S>G		No	ClinGen 1000Genomes ExAC gnomAD
CA368649476 rs1438527641	28	S>N		No	ClinGen gnomAD
CA163370790 rs200993465	29	S>F		No	ClinGen Ensembl
CA368649430 rs1240117858	31	T>I		No	ClinGen gnomAD
CA368649434 rs1240117858	31	T>N		No	ClinGen gnomAD
rs1584222212 CA368649442	31	T>P		No	ClinGen Ensembl
rs766494955 CA4406811	32	R>W		No	ClinGen ExAC gnomAD
rs1273528974 CA368649420	33	P>T		No	ClinGen gnomAD
CA4406810 rs763485972	34	Q>L		No	ClinGen ExAC gnomAD
CA368649400 rs1434832979	35	E>*		No	ClinGen TOPMed
CA4406808 rs369470948	36	V>M		No	ClinGen ESP ExAC TOPMed gnomAD
CA368649357 rs1445725552	38	A>V		No	ClinGen Ensembl
rs1239697931 CA368649353	39	E>*		No	ClinGen TOPMed gnomAD
rs1239697931 CA368649354	39	E>K		No	ClinGen TOPMed gnomAD
rs200814753 CA4406806	40	P>L		No	ClinGen 1000Genomes ExAC gnomAD
COSM1199000 CA368649338 rs1323341352	40	P>S	large_intestine [Cosmic]	No	ClinGen cosmic curated gnomAD
rs1323341352 CA368649341	40	P>T		No	ClinGen gnomAD
rs1326961991 CA368649329	41	R>K		No	ClinGen TOPMed gnomAD
CA368649327 rs1326961991	41	R>M		No	ClinGen TOPMed gnomAD
CA368649318 rs1307656509 COSM1446818	42	S>L	large_intestine Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated NCI-TCGA TOPMed
CA163370757 rs969687102	43	G>*		No	ClinGen gnomAD
CA368649311 rs969687102	43	G>R		No	ClinGen gnomAD
CA163370756 rs868016095	44	S>L		No	ClinGen TOPMed
CA4406803 rs778539700	45	G>E		No	ClinGen ExAC gnomAD
rs756791990 CA4406802	46	P>S		No	ClinGen ExAC gnomAD
TCGA novel	47	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs748856557 CA4406801	48	A>V		No	ClinGen ExAC gnomAD
CA368649252 rs1253938608	49	E>A		No	ClinGen gnomAD
CA4406800 rs777517613	49	E>D		No	ClinGen ExAC gnomAD
TCGA novel	49	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA4406799 rs756085636	50	A>V		No	ClinGen ExAC TOPMed gnomAD
rs755170919 CA4406796	51	E>K		No	ClinGen ExAC TOPMed gnomAD
rs762892730 CA4406793	52	P>L		No	ClinGen ExAC gnomAD
rs766619515 CA4406794	52	P>S		No	ClinGen ExAC TOPMed gnomAD
CA4406791 rs765594961	54	D>G		No	ClinGen ExAC TOPMed gnomAD
rs774424411 CA163370713 COSM743521	56	V>A	lung Variant assessed as Somatic; impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated NCI-TCGA gnomAD
CA368649174 rs1324983267	56	V>M		No	ClinGen gnomAD
rs148986263 CA4406789	59	T>M		No	ClinGen ESP ExAC TOPMed gnomAD
rs765929180 CA163370701	60	E>*		No	ClinGen ExAC TOPMed gnomAD
CA4406787 rs765929180	60	E>Q		No	ClinGen ExAC TOPMed gnomAD
rs774102605 CA368649128	61	R>P		No	ClinGen ExAC TOPMed gnomAD
CA4406786 rs774102605	61	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs1459459616 CA368649111	63	F>L		No	ClinGen gnomAD
rs34985488 VAR_036903 CA4406785	63	F>S		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
rs1562874738 CA368649097	64	E>K		No	ClinGen Ensembl
CA163370665 rs888719265	65	E>K		No	ClinGen TOPMed gnomAD
CA4406784 rs748682002	66	V>E		No	ClinGen ExAC
CA4406781 rs748166096	68	A>V		No	ClinGen ExAC gnomAD
CA4406778 rs751377393	69	I>L		No	ClinGen ExAC gnomAD
CA368649037 rs1280133277	69	I>M		No	ClinGen gnomAD
rs1562874715 CA368649040	69	I>T		No	ClinGen Ensembl
rs1212398263 CA368649027	70	S>L		No	ClinGen gnomAD
CA4406775 rs750463591	71	G>R		No	ClinGen ExAC gnomAD
rs201666132 CA4406774	72	G>D		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA368649017 rs1401059973	72	G>S		No	ClinGen gnomAD
rs201666132 CA4406773	72	G>V		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1310036075 CA368649008	73	I>L		No	ClinGen gnomAD
rs764724362 CA4406770	73	I>T		No	ClinGen ExAC gnomAD
CA4406767 rs770488727	74	Y>*		No	ClinGen ExAC gnomAD
CA4406768 rs199835653	74	Y>C		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs199835653 CA163370630	74	Y>F		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA4406769 rs761066274	74	Y>H		No	ClinGen ExAC gnomAD
rs762726335 CA4406766	77	L>P		No	ClinGen ExAC gnomAD
CA4406765 rs772576785	79	Y>S		No	ClinGen ExAC
rs769386646 CA4406764	81	P>L		No	ClinGen ExAC gnomAD
rs1041018030 CA163370619	84	Y>H		No	ClinGen TOPMed gnomAD
rs1041018030 CA368648895	84	Y>N		No	ClinGen TOPMed gnomAD
CA4406761 rs768594896	87	W>*		No	ClinGen ExAC gnomAD
CA368648825 rs373407624	89	R>P		No	ClinGen ESP ExAC TOPMed gnomAD
CA4406760 rs373407624	89	R>Q	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
TCGA novel	89	R>W	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs779964441 CA4406759	90	D>N		No	ClinGen ExAC gnomAD
CA368648808 rs141085888	91	P>A		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA4406757 rs141085888	91	P>T		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs757315538 CA4406755	92	D>N		No	ClinGen ExAC TOPMed gnomAD
CA4406753 rs764632562	93	R>C		No	ClinGen ExAC gnomAD
CA4406754 rs764632562	93	R>S		No	ClinGen ExAC gnomAD
rs1448395607 CA368648781	94	T>K		No	ClinGen gnomAD
rs1304625905 CA368648769	95	V>A		No	ClinGen gnomAD
rs1380587012 CA368648775	95	V>L		No	ClinGen gnomAD
CA368648763 rs1360699824	96	V>L		No	ClinGen gnomAD
CA4406751 rs374694349	97	L>P		No	ClinGen ESP ExAC gnomAD
CA4406750 rs374694349	97	L>Q		No	ClinGen ESP ExAC gnomAD
CA4406749 rs762482160	99	K>*		No	ClinGen ExAC gnomAD
CA368648739 rs762482160	99	K>E		No	ClinGen ExAC gnomAD
CA163370576 rs925908745	99	K>M		No	ClinGen gnomAD
rs1396458548 CA368648724	100	R>C		No	ClinGen TOPMed
rs371229816 CA4406748	100	R>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA163370568 rs371229816	100	R>P		No	ClinGen ESP ExAC TOPMed gnomAD
rs1396458548 CA368648729	100	R>S		No	ClinGen TOPMed
CA368648712 rs761254836 CA4406746	101	N>K		No	ClinGen ExAC gnomAD
CA4406745 rs776121685	102	G>R		No	ClinGen ExAC gnomAD
CA368648696 rs1415928277	104	V>M		No	ClinGen TOPMed gnomAD
CA4406706 rs369492361	109	S>*		No	ClinGen ESP ExAC TOPMed gnomAD
CA368647963 rs369492361	109	S>L	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
rs1296087606 CA368647969	109	S>T		No	ClinGen TOPMed gnomAD
rs767489413 CA4406705	110	V>A		No	ClinGen ExAC gnomAD
rs544430736 CA4406704	111	N>K		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1226983129 CA368647940	112	V>M		No	ClinGen gnomAD
CA368647926 rs1197547539	113	I>F		No	ClinGen TOPMed
rs762874878 CA4406701	114	D>H		No	ClinGen ExAC TOPMed gnomAD
rs762874878 CA4406702	114	D>Y		No	ClinGen ExAC TOPMed gnomAD
rs1231330505 CA368647904	115	A>S		No	ClinGen gnomAD
rs773518847 CA4406700	115	A>V		No	ClinGen ExAC gnomAD
rs965828709 CA163369777	116	G>E		No	ClinGen TOPMed
CA4406699 rs770154793	116	G>R		No	ClinGen ExAC TOPMed gnomAD
CA4406697 rs202212832	117	E>Q		No	ClinGen 1000Genomes ExAC gnomAD
CA4406696 rs375132035	118	T>K		No	ClinGen ESP ExAC gnomAD
rs1461717001 CA368647880	118	T>S		No	ClinGen TOPMed
CA368647871 rs1327907822	119	V>L		No	ClinGen TOPMed
rs1173332299 CA368647844	122	E>*	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA368647839 rs1474492634	122	E>V		No	ClinGen gnomAD
rs780362510 CA163369754	123	G>A		No	ClinGen ExAC gnomAD
rs780362510 CA4406694	123	G>E		No	ClinGen ExAC gnomAD
rs747518733 CA163369760	123	G>R		No	ClinGen ExAC TOPMed gnomAD
rs747518733 CA4406695	123	G>W		No	ClinGen ExAC TOPMed gnomAD
CA4406693 rs555655635	124	L>R		No	ClinGen 1000Genomes ExAC gnomAD
CA368647827 rs1425571710	124	L>V		No	ClinGen gnomAD
rs750804809 CA4406692	125	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA4406691 rs777346007	125	R>H		No	ClinGen ExAC TOPMed gnomAD
CA4406689 rs746429184	126	V>A		No	ClinGen ExAC TOPMed gnomAD
CA4406690 rs200194215	126	V>L		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA163369726 rs979673761	128	P>S		No	ClinGen TOPMed gnomAD
CA4406685 rs766442181	129	W>*		No	ClinGen ExAC gnomAD
CA4406686 rs572755206	129	W>R		No	ClinGen 1000Genomes ExAC gnomAD
CA4406684 rs762778679	130	E>K		No	ClinGen ExAC TOPMed gnomAD
rs372443350 CA4406683	131	R>C		No	ClinGen ESP ExAC TOPMed gnomAD
rs1390480121 CA368647767	131	R>H		No	ClinGen TOPMed gnomAD
rs1390480121 CA368647765	131	R>L		No	ClinGen TOPMed gnomAD
CA368647761 rs1250652671	132	G>R		No	ClinGen TOPMed
rs761997494 CA4406681	136	A>S		No	ClinGen ExAC gnomAD
CA4406680 rs776748256	136	A>V		No	ClinGen ExAC gnomAD
rs775923236 CA368647686	140	Q>*		No	ClinGen ExAC gnomAD
CA4406676 rs775923236	140	Q>K		No	ClinGen ExAC gnomAD
CA368647671 rs1348511961	141	R>H		No	ClinGen gnomAD
CA163369697 rs781560090	141	R>S		No	ClinGen TOPMed
CA4406675 rs557780669	142	F>S		No	ClinGen 1000Genomes ExAC gnomAD
rs779311549 CA4406673	143	C>R		No	ClinGen ExAC gnomAD
TCGA novel	144	S>L	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA368647639 rs1562873884	144	S>W		No	ClinGen Ensembl
CA368647628 rs1439712240	145	Q>P		No	ClinGen gnomAD
rs1457368624 CA368647607	147	V>A		No	ClinGen TOPMed
CA368647609 rs1330843739	147	V>I		No	ClinGen gnomAD
CA368647604 rs1407555880	148	K>E		No	ClinGen TOPMed gnomAD
CA368647596 rs1358126473	148	K>N		No	ClinGen Ensembl
rs569010209 CA4406669	149	R>G		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
TCGA novel	149	R>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA4406668 rs754397489	150	Q>*		No	ClinGen ExAC gnomAD
CA368647576 rs1382263848	150	Q>H		No	ClinGen gnomAD
rs550776605 CA4406667	150	Q>L		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
TCGA novel	151	H>R	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1487520089 CA368647537	154	V>A		No	ClinGen gnomAD
CA4406665 rs758476098	154	V>F		No	ClinGen ExAC gnomAD
CA4406666 rs758476098	154	V>I		No	ClinGen ExAC gnomAD
rs750227849 CA4406664	156	V>E		No	ClinGen ExAC gnomAD
rs1264972036 CA368647511	157	A>S		No	ClinGen gnomAD
rs1262458947 CA368647506	157	A>V		No	ClinGen gnomAD
rs762062727 CA4406662	158	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs1334566074 CA368647502	158	R>W		No	ClinGen TOPMed
rs1345343462 CA368647481	160	T>I		No	ClinGen gnomAD
rs1218229583 CA368647488	160	T>P		No	ClinGen TOPMed gnomAD
CA4406661 rs776673558	161	R>Q		No	ClinGen ExAC TOPMed gnomAD
rs1298067387 CA368647462	162	D>E		No	ClinGen gnomAD
CA368647459 rs746531603	163	D>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
rs746531603 CA163369648	163	D>Y		No	ClinGen TOPMed
rs1171901403 CA368647442 CA368647440	164	Q>H		No	ClinGen TOPMed gnomAD
CA4406659 rs373822203	164	Q>K		No	ClinGen ESP ExAC TOPMed gnomAD
rs772557794 CA4406658	164	Q>L		No	ClinGen ExAC TOPMed gnomAD
rs772557794 CA4406657	164	Q>R		No	ClinGen ExAC TOPMed gnomAD
CA4406656 rs746425054	166	G>D		No	ClinGen ExAC gnomAD
CA4406655 rs774671784	167	P>H		No	ClinGen ExAC gnomAD
CA163369639 rs369513802	167	P>S		No	ClinGen Ensembl
CA4406653 rs749686941	168	R>Q		No	ClinGen ExAC gnomAD
CA4406654 rs771163513	168	R>W		No	ClinGen ExAC gnomAD
CA4406652 rs780651588	169	E>K		No	ClinGen ExAC TOPMed gnomAD
rs1168006499 CA368647391	170	L>Q		No	ClinGen TOPMed
rs1489242416 CA368647363	172	K>N		No	ClinGen gnomAD
rs370796034 CA163369620	173	Y>H		No	ClinGen ESP TOPMed
CA368647348 rs1416886618	174	R>C		No	ClinGen TOPMed
rs1254747811 CA368647347	174	R>H		No	ClinGen gnomAD
CA4406650 rs746511872	178	K>N		No	ClinGen ExAC TOPMed gnomAD
rs779767462 CA4406649	179	Q>K		No	ClinGen ExAC TOPMed gnomAD
rs1264084341 CA368647242	180	G>D		No	ClinGen TOPMed gnomAD
CA368647232 rs759555931	181	I>N		No	ClinGen ExAC gnomAD
CA4406618 rs759555931	181	I>T		No	ClinGen ExAC gnomAD
rs1301625124 CA368647205	183	L>F		No	ClinGen gnomAD
CA368647199 rs1387936195	184	V>I		No	ClinGen TOPMed gnomAD
CA368647183 rs751664579	185	R>*		No	ClinGen ExAC gnomAD
rs751664579 CA4406617	185	R>G		No	ClinGen ExAC gnomAD
rs942544822 CA163369119	185	R>P		No	ClinGen gnomAD
rs1457506521 CA368647152	187	N>D		No	ClinGen TOPMed
CA368647154 rs1457506521	187	N>H		No	ClinGen TOPMed
rs917890345 CA163369115	188	A>G		No	ClinGen TOPMed
rs1310189813 CA368647140	188	A>T		No	ClinGen gnomAD
rs1292753301 CA368647120	190	A>T		No	ClinGen gnomAD
rs1156288736 CA368647100	191	L>P		No	ClinGen gnomAD
rs766793827 CA4406616	191	L>V		No	ClinGen ExAC TOPMed gnomAD
rs868407988 CA163369109	193	A>S		No	ClinGen Ensembl
CA163369105 rs987020746	194	G>R		No	ClinGen gnomAD
rs987020746 CA368647075	194	G>W		No	ClinGen gnomAD
CA4406615 rs763571946	195	L>M		No	ClinGen ExAC gnomAD
CA163369091 rs955345879	195	L>P		No	ClinGen TOPMed
CA368647055 rs1191019754	196	G>D		No	ClinGen gnomAD
CA4406614 rs773425116	196	G>R		No	ClinGen ExAC gnomAD
CA368647044 rs1562873438	197	A>E		No	ClinGen Ensembl
CA368647032 rs1356524808	198	R>P		No	ClinGen TOPMed
CA368647037 rs1489091557	198	R>W		No	ClinGen TOPMed gnomAD
rs1286871088 CA368647008	200	A>E		No	ClinGen gnomAD
CA368647005 rs1286871088	200	A>V		No	ClinGen gnomAD
CA368647002 rs1310719300	201	A>T		No	ClinGen gnomAD
rs977802076 CA163369085	201	A>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA368646972 rs879584444	203	R>G		No	ClinGen TOPMed gnomAD
CA368646968 rs1399359434	203	R>Q		No	ClinGen gnomAD
rs1022058799 CA163369072	207	T>I		No	ClinGen gnomAD
CA368646925 rs1584219457	207	T>P		No	ClinGen Ensembl
CA4406609 rs745306009	210	P>L		No	ClinGen ExAC gnomAD
CA368646884 rs1175782104	210	P>S		No	ClinGen gnomAD
CA4406607 rs778549341	214	E>K		No	ClinGen ExAC TOPMed gnomAD
CA368646817 rs770754694	216	V>L		No	ClinGen ExAC TOPMed gnomAD
rs770754694 CA4406606	216	V>M		No	ClinGen ExAC TOPMed gnomAD
CA4406605 rs749290510	217	S>C		No	ClinGen ExAC TOPMed gnomAD
CA368646800 rs749290510	217	S>F		No	ClinGen ExAC TOPMed gnomAD
rs1313696395 CA368646769	220	G>C		No	ClinGen gnomAD
rs752502819 CA4406602	221	G>S		No	ClinGen ExAC TOPMed gnomAD
rs781324827 CA368646749	222	D>H		No	ClinGen ExAC TOPMed gnomAD
rs781324827 CA368646750	222	D>N	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA4406601 rs781324827	222	D>Y		No	ClinGen ExAC TOPMed gnomAD
rs1393850407 CA368646735	223	V>L		No	ClinGen TOPMed gnomAD
rs1400890621 CA368646716	224	A>V		No	ClinGen gnomAD
CA368646713 rs1401888894	225	R>G		No	ClinGen TOPMed
rs1467290271 CA368646708	225	R>H		No	ClinGen gnomAD
rs751579356 CA4406599	226	L>F		No	ClinGen ExAC gnomAD
CA4406598 rs766528598	227	L>P		No	ClinGen ExAC TOPMed gnomAD
rs370171748 CA4406597	230	P>L		No	ClinGen ESP ExAC TOPMed gnomAD
CA4406595 rs765866104	232	V>A		No	ClinGen ExAC TOPMed gnomAD
CA368646634 rs1021796848	232	V>L		No	ClinGen TOPMed gnomAD
CA163369010 rs1021796848	232	V>M		No	ClinGen TOPMed gnomAD
rs1584219349 CA368646622	233	Q>*		No	ClinGen Ensembl
CA368646613 rs1255593367	234	R>C		No	ClinGen TOPMed gnomAD
CA368646606 rs1201199776	234	R>H		No	ClinGen TOPMed gnomAD
CA368646615 rs1255593367	234	R>S		No	ClinGen TOPMed gnomAD
rs762206776 CA4406594	235	D>E		No	ClinGen ExAC TOPMed gnomAD
CA163369007 rs1035211527	235	D>N		No	ClinGen TOPMed gnomAD
TCGA novel	235	D>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs777136357 CA4406593	236	V>L		No	ClinGen ExAC gnomAD
CA4406592 rs377192349	237	L>F		No	ClinGen ESP ExAC TOPMed gnomAD
CA4406591 rs759287497	237	L>R		No	ClinGen ExAC TOPMed gnomAD
CA4406588 rs748775852	239	G>S		No	ClinGen ExAC gnomAD
rs267601204 CA163368964	240	G>R		No	ClinGen gnomAD
rs267601204 CA368646544	240	G>W		No	ClinGen gnomAD
CA368646524 rs1329726933	241	T>S		No	ClinGen gnomAD
CA163368947 rs769728216	242	I>L		No	ClinGen ExAC TOPMed gnomAD
CA4406586 rs769728216	242	I>V		No	ClinGen ExAC TOPMed gnomAD
CA163368941 rs771705925	243	I>M		No	ClinGen TOPMed
rs1446947809 CA368646502	243	I>N		No	ClinGen TOPMed gnomAD
rs1307860484 CA368646510	243	I>V		No	ClinGen gnomAD
CA4406585 rs747933304	244	Q>P		No	ClinGen ExAC gnomAD
CA4406584 rs781024841	245	D>E		No	ClinGen ExAC gnomAD
CA368646441 rs1367942785	247	Q>*		No	ClinGen gnomAD
CA4406582 rs551457672	250	R>P		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs551457672 CA163368930	250	R>Q		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA368646373 rs1387048863	253	E>K		No	ClinGen TOPMed
CA4406580 rs758454710	254	S>N		No	ClinGen ExAC gnomAD
rs34496028 CA4406577	257	R>C		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA163368924 rs898287785	257	R>P		No	ClinGen TOPMed
CA4406578 rs34496028	257	R>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA163368899 rs1037529011	258	L>P		No	ClinGen TOPMed
CA4406576 rs754238631	259	L>M		No	ClinGen ExAC gnomAD
CA368646304 rs1265487544	259	L>P		No	ClinGen gnomAD
rs760979596 CA4406574	260	A>E		No	ClinGen ExAC TOPMed gnomAD
CA163368888 rs760979596	260	A>V		No	ClinGen ExAC TOPMed gnomAD
rs1050958630 CA163368883	261	A>D		No	ClinGen gnomAD
CA368646275 rs1173329732	262	K>R		No	ClinGen gnomAD
rs1463473773 CA368646262	263	G>D		No	ClinGen TOPMed
rs1436781056 CA368646245	264	L>Q		No	ClinGen gnomAD
CA368646252 rs1331349992	264	L>V		No	ClinGen gnomAD
rs550665110 CA4406572	267	R>L		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs550665110 CA163368879	267	R>P		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA368646157 rs1426565693	269	D>H		No	ClinGen gnomAD
CA368646112 rs1253705388	271	R>G		No	ClinGen TOPMed
CA4406569 rs769707992	272	A>E		No	ClinGen ExAC gnomAD
rs529394330 CA368646092	272	A>S		No	ClinGen 1000Genomes TOPMed gnomAD
CA163368870 rs529394330	272	A>T		No	ClinGen 1000Genomes TOPMed gnomAD
rs1450964149 CA368646080	273	R>G		No	ClinGen gnomAD
rs1562873227 CA368646059	274	P>A		No	ClinGen Ensembl
CA368646049 rs1268047723	274	P>L		No	ClinGen gnomAD
CA368646047 rs1234470087	275	R>G		No	ClinGen gnomAD
TCGA novel	275	R>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA368646035 rs1224628943	275	R>L		No	ClinGen gnomAD
CA163368842 rs978376868	276	V>M		No	ClinGen gnomAD
CA368645999 rs1355458562	277	L>F		No	ClinGen gnomAD
rs967946590 CA163368827	279	L>P		No	ClinGen Ensembl
rs1324709816 CA368645940	280	C>R		No	ClinGen TOPMed gnomAD
COSM4161667 CA368645933 rs1407332139	280	C>S	thyroid [Cosmic]	No	ClinGen cosmic curated gnomAD
CA368645913 rs1161795214	281	T>A		No	ClinGen TOPMed
rs768456612 CA4406563	281	T>M		No	ClinGen ExAC TOPMed gnomAD
CA368645853 rs1410527406	284	F>L		No	ClinGen gnomAD
CA4406561 rs780265632	285	P>R		No	ClinGen ExAC gnomAD
CA368645831 rs1562873187	286	I>L		No	ClinGen Ensembl
CA368645817 rs1256631359	286	I>T		No	ClinGen TOPMed gnomAD
rs1477543063 CA368645806	287	P>T		No	ClinGen gnomAD
CA4406559 rs201659057	289	G>E		No	ClinGen 1000Genomes ExAC gnomAD
CA368645757 rs1201432121	289	G>R		No	ClinGen gnomAD
rs1584219026 CA368645723	290	G>V		No	ClinGen Ensembl
rs778723713 CA4406558	291	D>H		No	ClinGen ExAC TOPMed gnomAD
CA368645708 rs778723713	291	D>Y		No	ClinGen ExAC TOPMed gnomAD
rs754359293 CA4406556	292	G>R		No	ClinGen ExAC TOPMed gnomAD
rs1275995364 CA368645683	292	G>V		No	ClinGen gnomAD
rs756447039 CA4406554	293	T>I		No	ClinGen ExAC gnomAD
rs764722492 CA4406555	293	T>S		No	ClinGen ExAC gnomAD
CA368645659 rs1284353931	294	W>*		No	ClinGen gnomAD
CA368645647 rs1291501381	294	W>C		No	ClinGen TOPMed
rs937986290 CA163368772	296	Y>C		No	ClinGen TOPMed
CA368645605 rs1225868464	296	Y>H		No	ClinGen gnomAD
rs753012590 CA368645578	298	N>I		No	ClinGen ExAC gnomAD
rs753012590 CA4406553	298	N>S		No	ClinGen ExAC gnomAD
CA4406551 COSM3831461 rs762571452	300	D>E	breast [Cosmic]	No	ClinGen cosmic curated ExAC TOPMed gnomAD
CA368645557 rs1410263733	300	D>Y		No	ClinGen TOPMed
rs926897640 CA163368743	302	F>V		No	ClinGen TOPMed
CA163368741 rs1003733858	303	G>C		No	ClinGen TOPMed gnomAD
CA368645527 rs1003733858	303	G>R		No	ClinGen TOPMed gnomAD
rs749914075 CA4406550	304	S>G		No	ClinGen ExAC gnomAD
CA368645508 rs1323650181	304	S>N		No	ClinGen TOPMed
rs371351222 CA4406549	305	D>H		No	ClinGen ESP ExAC TOPMed gnomAD
CA368645461 rs1584218933	306	G>D		No	ClinGen Ensembl
CA368645451 rs1422899810	307	A>P		No	ClinGen gnomAD
CA368645374 rs1476070521	310	Q>H		No	ClinGen gnomAD
rs776502659 CA4406547	311	S>N		No	ClinGen ExAC TOPMed gnomAD
CA368645354 rs1352228436	311	S>R		No	ClinGen gnomAD
CA4406546 rs768491747	315	W>C		No	ClinGen ExAC gnomAD
rs760447778 CA368645296	316	H>N		No	ClinGen ExAC gnomAD
CA4406544 rs775212418	316	H>R		No	ClinGen ExAC gnomAD
rs760447778 CA4406545	316	H>Y		No	ClinGen ExAC gnomAD
CA368645251 rs772322657	319	R>C		No	ClinGen ExAC TOPMed gnomAD
rs1416587871 CA368645243	319	R>H		No	ClinGen TOPMed
CA4406543 rs772322657	319	R>S		No	ClinGen ExAC TOPMed gnomAD
rs746139290 CA4406542	321	A>V		No	ClinGen ExAC gnomAD
TCGA novel	322	P>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs771088891 CA4406540	323	R>H		No	ClinGen ExAC gnomAD
CA368645141 rs1447530136	325	V>A		No	ClinGen gnomAD
rs1282544886 CA368645145	325	V>F		No	ClinGen gnomAD
CA368645151 rs1282544886	325	V>I		No	ClinGen gnomAD
TCGA novel	328	N>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA368645102 rs1341365893	328	N>T		No	ClinGen gnomAD
rs1399280161 CA368645061	330	M>I		No	ClinGen gnomAD
CA4406539 rs749396806	330	M>L		No	ClinGen ExAC gnomAD
rs778279872 CA4406538	330	M>T		No	ClinGen ExAC TOPMed gnomAD
rs1309402164 CA368645033	331	C>*		No	ClinGen TOPMed
rs1281726522 CA368645007	332	Q>*		No	ClinGen TOPMed gnomAD
rs1281726522 CA368645009	332	Q>E		No	ClinGen TOPMed gnomAD
rs1226486881 CA368644962	334	F>L		No	ClinGen TOPMed
CA4406537 rs756647344	335	L>R		No	ClinGen ExAC TOPMed gnomAD
rs1342876818 CA368644917	336	E>*		No	ClinGen TOPMed
CA368644895 rs1410965689	336	E>D		No	ClinGen gnomAD
CA4406535 rs781460191	337	P>L		No	ClinGen ExAC
CA368644858 rs1180817482	338	Q>H		No	ClinGen gnomAD
CA4406534 rs758017412	340	W>*		No	ClinGen ExAC gnomAD
rs767720651 CA163368656	342	Q>R		No	ClinGen Ensembl
rs1207577774 CA368644784	344	A>S		No	ClinGen TOPMed
rs1039039144 CA368644754	345	D>E		No	ClinGen TOPMed
CA368644760 rs1272739308	345	D>G		No	ClinGen TOPMed
CA4406532 rs750036457	347	C>R		No	ClinGen ExAC gnomAD
rs764891260 CA4406531	347	C>S		No	ClinGen ExAC gnomAD
rs1309823104 CA368644678	350	G>R		No	ClinGen TOPMed gnomAD
COSM4153705 CA368644676 rs1309823104	350	G>W	ovary [Cosmic]	No	ClinGen cosmic curated TOPMed gnomAD
CA4406529 rs753349664	352	G>R		No	ClinGen ExAC
rs775329336 CA4406526	354	E>A		No	ClinGen ExAC gnomAD
rs775329336 CA4406525	354	E>G		No	ClinGen ExAC gnomAD
rs764083992 CA4406527	354	E>Q		No	ClinGen ExAC gnomAD
rs1472111222 CA368644543	358	G>S		No	ClinGen TOPMed
CA163368599 rs890557561	359	Y>*		No	ClinGen gnomAD
CA368644531 rs1181716223	359	Y>D		No	ClinGen TOPMed
rs1412454836 CA368644518	360	T>I		No	ClinGen TOPMed
rs540857589 CA4406522	361	E>K	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA gnomAD
rs771287019 CA4406521	362	Q>L		No	ClinGen ExAC gnomAD
CA368644473 rs1368282732	363	Y>*		No	ClinGen TOPMed
rs201313983 CA4406520	366	E>G		No	ClinGen ESP ExAC TOPMed gnomAD
rs1348125127 CA368644455	366	E>K		No	ClinGen gnomAD
CA368644432 rs1386567207	368	D>N		No	ClinGen gnomAD
rs770313623 CA4406518	370	I>L		No	ClinGen ExAC gnomAD
CA368644414 rs1360641353	370	I>R		No	ClinGen TOPMed

No associated diseases with Q8N8M0

1 regional properties for Q8N8M0

Type	Name	Position	InterPro Accession
domain	GNAT domain	53 - 188	IPR000182

Functions

		Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

No GO annotations of cellular component

Name	Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name	Definition
acetyltransferase activity	Catalysis of the transfer of an acetyl group to an acceptor molecule.
acyltransferase activity, transferring groups other than amino-acyl groups	Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor).

No GO annotations of biological process

Name	Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
No homologous proteins

10	20	30	40	50	60
MKLEASCGTA	TSEVPKPEKK	TARDAEPSSE	TRPQEVEAEP	RSGSGPEAEA	EPLDFVVATE
70	80	90	100	110	120
REFEEVLAIS	GGIYGGLDYL	PSRYHSWLRD	PDRTVVLAKR	NGGVIALESV	NVIDAGETVL
130	140	150	160	170	180
VEGLRVAPWE	RGKGVAGLLQ	RFCSQLVKRQ	HPGVKVARLT	RDDQLGPREL	KKYRLITKQG
190	200	210	220	230	240
ILLVRFNASA	LLAGLGARLA	ALRTSGTFSP	LPTEAVSEAG	GDVARLLLSP	SVQRDVLPGG
250	260	270	280	290	300
TIIQDWQPYR	PSESNLRLLA	AKGLEWRVDS	RARPRVLTLC	TRPFPIPHGG	DGTWRYLNID
310	320	330	340	350	360
AFGSDGAQVQ	SQLLWHLQRQ	APRLVGLNVM	CQLFLEPQLW	SQLADFCQVG	LGLELVKGYT

EQYLLEADI