Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8N8J0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8N8J0-F1 | Predicted | AlphaFoldDB |
No variants for Q8N8J0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q8N8J0 | |||||
No associated diseases with Q8N8J0
1 regional properties for Q8N8J0
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | PI4-kinase, N-terminal | 1 - 167 | IPR045495 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| membrane | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| 1-phosphatidylinositol 4-kinase activity | Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = 1-phosphatidyl-1D-myo-inositol 4-phosphate + ADP + 2 H(+). |
| phosphatidylinositol kinase activity | Catalysis of the reaction: ATP + a phosphatidylinositol = ADP + a phosphatidylinositol phosphate. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| phosphatidylinositol phosphate biosynthetic process | The chemical reactions and pathways resulting in the formation of phosphatidylinositol phosphate. |
| phosphatidylinositol-mediated signaling | The series of molecular signals in which a cell uses a phosphatidylinositol-mediated signaling to convert a signal into a response. Phosphatidylinositols include phosphatidylinositol (PtdIns) and its phosphorylated derivatives. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTVEQKFGLF | SAEIKEADPL | AASEASQPKP | CPPEVTPHYI | WIDFLVQRFE | IAKYCSSDQV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EIFSSLLQRS | MSLNIGGAKG | SMNRHVAAIG | PRFKLLTLGL | SLLHADVVPN | ATIRNVLREK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IYSTAFDYFS | CPPKFPTQGE | KRLREDISIM | IKFWTAMFSD | KKYLTASQLV | PPADIGDLRE |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QLVEENTGSL | SGPAKDFYQR | EFDFFNKITN | VSAVIKPYPK | GDQRKKACLS | ALSEVTVQPG |
| 250 | 260 | ||||
| CSLPSNPEAI | VLDVDYKSGT | PM |