Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
2 structures for Q8MPF7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 5XXU | EM | 335 A | A | 1-287 | PDB |
| AF-Q8MPF7-F1 | Predicted | AlphaFoldDB |
No variants for Q8MPF7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q8MPF7 | |||||
No associated diseases with Q8MPF7
5 regional properties for Q8MPF7
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Peptidase M12B, ADAM/reprolysin | 193 - 389 | IPR001590 |
| domain | Disintegrin domain | 405 - 477 | IPR001762 |
| domain | Peptidase M12B, propeptide | 48 - 150 | IPR002870 |
| conserved_site | Disintegrin, conserved site | 433 - 452 | IPR018358 |
| domain | Reprolysin domain, adamalysin-type | 193 - 387 | IPR034027 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosolic small ribosomal subunit | The small subunit of a ribosome located in the cytosol. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| structural constituent of ribosome | The action of a molecule that contributes to the structural integrity of the ribosome. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| ribosomal small subunit assembly | The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the small ribosomal subunit. |
| translation | The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAADKQAKLS | LQEDSIAKML | ICKAHIGTKN | VEHKMRPYVF | KSTSEGIHLI | NLAKTWEKIL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| MAARVIVAIE | NPADVLVISA | RPYGSRAVLK | FSQYVGAQAI | AGRWTPGMLT | NQITQKFMEP |
| 130 | 140 | 150 | 160 | 170 | 180 |
| RLLIVTDPRT | DAQAVRESAY | ANVPVIALCD | TDSPLEHVDI | CIPCNNKGKE | SIALMYWLLA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| REVLYLRGEL | PSRSVPWDVM | VDMFLWRDPE | EFERKERLED | EEAAPHTAQA | DATQWGADAA |
| 250 | 260 | 270 | 280 | ||
| AADWKQAGAD | WTGPAAGGAG | GEWDQSAVAA | EGEWGGGRPG | VAVGEPW |