Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q8MIB8

Entry ID Method Resolution Chain Position Source
AF-Q8MIB8-F1 Predicted AlphaFoldDB

No variants for Q8MIB8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8MIB8

No associated diseases with Q8MIB8

4 regional properties for Q8MIB8

Type Name Position InterPro Accession
domain PA domain 237 - 354 IPR003137
domain Transferrin receptor-like, dimerisation domain 647 - 758 IPR007365
domain Peptidase M28 397 - 585 IPR007484
domain Transferrin receptor protein 1/2, PA domain 211 - 386 IPR037324

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

1 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

1 GO annotations of biological process

Name Definition
regulation of DNA-templated transcription Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEATADGPAE TQSPVEKDSP VKTQSPAQDT SITSRNNADR GRVLALPEHK KKRHGNLPAK
70 80 90 100 110 120
SVKILRDWMY KHRFRAYPSE EEKQMLSEKT NLSLLQVSNW FINARRRILP DMLQQCGNDP
130 140 150 160 170 180
VIGHKMGKNA HATHLQSTDA SVPASSGPSG PDNVQSLPLW PLPKGQMSGE KLPDPESAPS
190 200 210 220 230 240
QKLTGKAQPE KKVKFSITSP FSPEPVSPEE YADFSSFQLL VDAAVQRAAE LELEKKQDPN
P