Q8LGE9
Gene name |
At5g41760 (K16L22.3) |
Protein name |
CMP-sialic acid transporter 1 |
Names |
CMP-SA-Tr 1, CMP-Sia-Tr 1 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT5G41760 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8LGE9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8LGE9-F1 | Predicted | AlphaFoldDB |
33 variants for Q8LGE9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH03314736 | 3 | A>D | No | 1000Genomes | |
| tmp_5_16707002_G_T | 9 | V>F | No | 1000Genomes | |
| ENSVATH14563597 | 12 | L>I | No | 1000Genomes | |
| ENSVATH07293985 | 46 | V>F | No | 1000Genomes | |
| ENSVATH07293986 | 47 | F>L | No | 1000Genomes | |
| ENSVATH07293992 | 55 | F>L | No | 1000Genomes | |
| ENSVATH07293993 | 56 | L>F | No | 1000Genomes | |
| ENSVATH07293993 | 56 | L>I | No | 1000Genomes | |
| ENSVATH12343336 | 61 | R>Q | No | 1000Genomes | |
| ENSVATH03314779 | 68 | S>A | No | 1000Genomes | |
| ENSVATH00694401 | 76 | S>N | No | 1000Genomes | |
| ENSVATH03314785 | 119 | I>L | No | 1000Genomes | |
| ENSVATH03314785 | 119 | I>V | No | 1000Genomes | |
| ENSVATH07293999 | 133 | Q>R | No | 1000Genomes | |
| ENSVATH07294000 | 138 | G>A | No | 1000Genomes | |
| ENSVATH00694407 | 155 | A>P | No | 1000Genomes | |
| tmp_5_16708351_A_G | 162 | T>A | No | 1000Genomes | |
| ENSVATH12343343 | 173 | L>F | No | 1000Genomes | |
| ENSVATH03314800 | 176 | G>S | No | 1000Genomes | |
| ENSVATH14563601 | 195 | T>S | No | 1000Genomes | |
| tmp_5_16708660_G_A | 218 | D>N | No | 1000Genomes | |
| ENSVATH12343458 | 280 | V>L | No | 1000Genomes | |
| ENSVATH07294033 | 314 | T>A | No | 1000Genomes | |
| ENSVATH07294034 | 321 | T>I | No | 1000Genomes | |
| tmp_5_16709152_C_A | 324 | A>E | No | 1000Genomes | |
| ENSVATH12343463 | 324 | A>S | No | 1000Genomes | |
| ENSVATH07294036 | 326 | A>G | No | 1000Genomes | |
| tmp_5_16709157_G_A | 326 | A>T | No | 1000Genomes | |
| ENSVATH07294037 | 329 | L>F | No | 1000Genomes | |
| tmp_5_16709175_G_A | 332 | V>I | No | 1000Genomes | |
| ENSVATH12343464 | 336 | E>A | No | 1000Genomes | |
| ENSVATH12343495 | 340 | S>C | No | 1000Genomes | |
| tmp_5_16709199_T_A | 340 | S>T | No | 1000Genomes |
No associated diseases with Q8LGE9
No regional properties for Q8LGE9
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q8LGE9 | |||
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of Golgi membrane | The component of the Golgi membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| pyrimidine nucleotide-sugar transmembrane transporter activity | Enables the transfer of a pyrimidine nucleotide-sugar from one side of a membrane to the other. Pyrimidine nucleotide-sugars are pyrimidine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative. |
| sialic acid transmembrane transporter activity | Enables the transfer of sialic acid from one side of a membrane to the other. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| carbohydrate transport | The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are a group of organic compounds based of the general formula Cx(H2O)y. |
| sialic acid transport | The directed movement of sialic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9BS91 | SLC35A5 | Probable UDP-sugar transporter protein SLC35A5 | Homo sapiens (Human) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAATPWYFVA | VLLTILTSSQ | GILTTLSQSD | GGYKYDYATV | PFLAEVFKLI | ISGLFLWREM |
| 70 | 80 | 90 | 100 | 110 | 120 |
| RTSSSTTSRI | TTDWKSVRLF | VIPSLIYLIH | NNVQFATLTY | VDTSTYQIMG | NLKIVTTGIL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| FRLFLKRKLS | KLQWMAIGLL | AVGTTTSQVK | GCGEASCDSL | FTAPIQGYLL | GILSAGLSAL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| AGIYTEFLMK | RNNDTLYWQN | LQLYTFGSLF | NVARLIADDF | RHGFEKGPWW | QRIFDGYSIT |
| 250 | 260 | 270 | 280 | 290 | 300 |
| TWLVVLNLGS | TGLLVSWLMK | YADNIVKVYS | TSMAMLLTMV | ASIYLFSFKP | TLQLFLGIVI |
| 310 | 320 | 330 | |||
| CIMSLHMYFA | PPHTLVDLPV | TNEAHAKTLK | QVVVEEKTDS |