Q8LED3
Gene name |
TBL3 (At5g01360, T10O8.70) |
Protein name |
Protein trichome birefringence-like 3 |
Names |
|
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT5G01360 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8LED3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8LED3-F1 | Predicted | AlphaFoldDB |
43 variants for Q8LED3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_5_149253_G_A | 22 | L>F | No | 1000Genomes | |
| ENSVATH06902462 | 22 | L>P | No | 1000Genomes | |
| tmp_5_149240_C_G | 26 | G>A | No | 1000Genomes | |
| tmp_5_149177_G_A | 47 | S>L | No | 1000Genomes | |
| ENSVATH00806342 | 56 | S>P | No | 1000Genomes | |
| ENSVATH10477933 | 64 | S>T | No | 1000Genomes | |
| ENSVATH06902460 | 66 | P>L | No | 1000Genomes | |
| ENSVATH06902459 | 67 | K>E | No | 1000Genomes | |
| tmp_5_148882_G_T | 108 | L>I | No | 1000Genomes | |
| tmp_5_148876_T_C | 110 | T>A | No | 1000Genomes | |
| ENSVATH03002597 | 124 | M>I | No | 1000Genomes | |
| tmp_5_148833_A_G | 124 | M>T | No | 1000Genomes | |
| tmp_5_148830_T_C | 125 | K>R | No | 1000Genomes | |
| tmp_5_148783_C_A | 141 | D>Y | No | 1000Genomes | |
| ENSVATH06902451 | 157 | L>I | No | 1000Genomes | |
| ENSVATH06902449 | 197 | K>I | No | 1000Genomes | |
| tmp_5_148367_C_A | 208 | A>S | No | 1000Genomes | |
| tmp_5_148364_T_A | 209 | T>S | No | 1000Genomes | |
| tmp_5_148232_T_C | 253 | I>V | No | 1000Genomes | |
| tmp_5_148198_C_T | 264 | S>N | No | 1000Genomes | |
| tmp_5_148196_C_T | 265 | G>S | No | 1000Genomes | |
| ENSVATH06902447 | 267 | R>H | No | 1000Genomes | |
| tmp_5_148177_A_T | 271 | L>Q | No | 1000Genomes | |
| ENSVATH06902446 | 274 | S>A | No | 1000Genomes | |
| ENSVATH03002580 | 279 | E>A | No | 1000Genomes | |
| ENSVATH03002580 | 279 | E>G | No | 1000Genomes | |
| tmp_5_148139_C_T | 284 | A>T | No | 1000Genomes | |
| ENSVATH10477926 | 287 | T>I | No | 1000Genomes | |
| ENSVATH03002579 | 288 | Q>E | No | 1000Genomes | |
| ENSVATH03002578 | 288 | Q>P | No | 1000Genomes | |
| tmp_5_148117_T_A | 291 | Y>F | No | 1000Genomes | |
| ENSVATH06902445 | 314 | F>S | No | 1000Genomes | |
| ENSVATH06902445 | 314 | F>Y | No | 1000Genomes | |
| tmp_5_147883_T_C | 344 | K>E | No | 1000Genomes | |
| tmp_5_147832_C_T | 361 | V>M | No | 1000Genomes | |
| ENSVATH06902442 | 363 | S>N | No | 1000Genomes | |
| ENSVATH06902441 | 369 | T>N | No | 1000Genomes | |
| tmp_5_147758_G_C | 385 | I>M | No | 1000Genomes | |
| ENSVATH06902440 | 391 | V>I | No | 1000Genomes | |
| tmp_5_147646_G_A | 423 | P>S | No | 1000Genomes | |
| ENSVATH03002561 | 425 | T>I | No | 1000Genomes | |
| ENSVATH13868429 | 427 | N>S | No | 1000Genomes | |
| tmp_5_147620_C_A | 431 | L>F | No | 1000Genomes |
No associated diseases with Q8LED3
1 regional properties for Q8LED3
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Trichome birefringence-like, N-terminal domain | 90 - 143 | IPR025846 |
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| Golgi apparatus | A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. |
| Golgi membrane | The lipid bilayer surrounding any of the compartments of the Golgi apparatus. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| O-acetyltransferase activity | Catalysis of the transfer of an acetyl group to an oxygen atom on the acceptor molecule. |
| xylan O-acetyltransferase activity | Catalysis of the reaction: acetyl-CoA + a xylan= CoA + an acetylated xylan. |
5 GO annotations of biological process
| Name | Definition |
|---|---|
| cellulose biosynthetic process | The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation. |
| pectin biosynthetic process | The chemical reactions and pathways resulting in the formation of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues. |
| plant-type cell wall modification | The series of events leading to chemical and structural alterations of an existing cellulose and pectin-containing cell wall that can result in loosening, increased extensibility or disassembly. An example of this is found in Arabidopsis thaliana. |
| xylan acetylation | The addition of one or more acetyl groups to a xylan molecule. |
| xylan biosynthetic process | The chemical reactions and pathways resulting in the formation of xylan, a polymer containing a beta-1,4-linked D-xylose backbone. |
3 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q1PFD9 | TBL31 | Protein trichome birefringence-like 31 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q940H3 | TBL36 | Protein trichome birefringence-like 36 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8VYS5 | TBL18 | Protein trichome birefringence-like 18 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSFLIPNRGV | GGTKIPLSII | VLVLCGFMFF | ILLYTERISL | LSSSSSSSSS | FFKLKSCPRK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| DVSSKPKEKI | RKERSEILEV | LDDRFEFDPE | ECNVAAGKWV | YNSSIEPLYT | DRSCPYIDRQ |
| 130 | 140 | 150 | 160 | 170 | 180 |
| FSCMKNGQPE | TDYLRWEWQP | DDCTIPRFSP | KLAMNKLRGK | RLLFVGDSLQ | RSQWESFVCL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VESIIPEGEK | SMKRSQKYFV | FKAKEYNATI | EFYWAPYIVE | SNTDIPVISD | PKKRIVKVDS |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VKDRAKFWEG | ADILVFNTYV | WWMSGLRMKA | LWGSFGNGES | GAEALDTQVA | YRLGLKTWAN |
| 310 | 320 | 330 | 340 | 350 | 360 |
| WVDSTVDPNK | TRVFFTTMSP | THTRSADWGK | PNGTKCFNET | KPIKDKKFWG | TGSNKQMMKV |
| 370 | 380 | 390 | 400 | 410 | 420 |
| VSSVIKHMTT | HVTVINITQL | SEYRIDAHTS | VYTETGGKIL | TAEQRADPMH | HADCIHWCLP |
| 430 | |||||
| GLPDTWNRIL | LAHL |