Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q8LDG7

Entry ID Method Resolution Chain Position Source
AF-Q8LDG7-F1 Predicted AlphaFoldDB

23 variants for Q8LDG7

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH10754838 9 R>W No 1000Genomes
ENSVATH05854969 26 Y>F No 1000Genomes
tmp_3_6221166_A_C 33 N>T No 1000Genomes
ENSVATH05854971 56 I>L No 1000Genomes
ENSVATH07965388 58 T>N No 1000Genomes
tmp_3_6221352_G_A 65 D>N No 1000Genomes
ENSVATH10754885 85 S>N No 1000Genomes
ENSVATH05854974 106 I>T No 1000Genomes
ENSVATH13939956 136 M>I No 1000Genomes
ENSVATH05854977 152 L>I No 1000Genomes
ENSVATH05854985 185 D>E No 1000Genomes
ENSVATH02159127 219 S>R No 1000Genomes
ENSVATH00330851 222 R>Q No 1000Genomes
ENSVATH00330852 233 M>I No 1000Genomes
ENSVATH00330853 247 M>T No 1000Genomes
ENSVATH10754890 255 V>A No 1000Genomes
tmp_3_6222483_G_A 262 V>I No 1000Genomes
ENSVATH00330855
ENSVATH13939957
263 T>S No 1000Genomes
ENSVATH00330856 267 L>Q No 1000Genomes
ENSVATH00330857 277 T>A No 1000Genomes
tmp_3_6222532_G_C 278 S>T No 1000Genomes
ENSVATH00330858 292 C>F No 1000Genomes
ENSVATH10754893 305 G>D No 1000Genomes

No associated diseases with Q8LDG7

No regional properties for Q8LDG7

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q8LDG7

Functions

Description
EC Number
Subcellular Localization
  • Peroxisome membrane ; Single-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of peroxisomal membrane The component of the peroxisomal membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
protein-macromolecule adaptor activity The binding activity of a protein that brings together two or more macromolecules in contact, permitting those molecules to function in a coordinated way. The adaptor can bring together two proteins, or a protein and another macromolecule such as a lipid or a nucleic acid.

1 GO annotations of biological process

Name Definition
protein import into peroxisome membrane The targeting of proteins into the peroxisomal membrane. The process is not well understood, but both signals and mechanism differ from those involved in peroxisomal matrix protein import.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q8S9K7 PEX3-2 Peroxisome biogenesis protein 3-2 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MDLVRGLWRK HRRKILVTTT CLGSGYLLYK LYNAHTRKLA DLERELANER ENDEIIKTQM
70 80 90 100 110 120
KAHFDNIQMI ADTTTLPHAI HHLSSRVVEE IDVSSIMDKL SKGKGILIPS EKLQLWNELK
130 140 150 160 170 180
ILSFTRMVLS LWSVTMLSLY IRVQVNILGR HLYIDTARGL GSSHLLDELD LIERDDEQKF
190 200 210 220 230 240
LTSADFLATS GMPSLISNMQ NAVKEVLKGK QLKDVLTTSA LRETVMRILD VFMSTGSPHH
250 260 270 280 290 300
WVDYLMMSQD ATTDVSSSDA TVTKFHLLIT ETREVLTSND FSNVAEISLK CCAVALVEEM
310 320 330 340 350
ETQTGLATGM QLAKLLPQIE KTMPEISAEP EKNRFLQLIR DLPEVKLFFT LLYANMPQ