Q8LCV1
Gene name |
PLP3B (At5g66410, K1F13.6) |
Protein name |
Thioredoxin domain-containing protein PLP3B |
Names |
Phosducin-like protein 3B |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT5G66410 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8LCV1
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8LCV1-F1 | Predicted | AlphaFoldDB |
13 variants for Q8LCV1
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_5_26520331_G_A | 40 | R>K | No | 1000Genomes | |
| ENSVATH03483572 | 81 | Q>L | No | 1000Genomes | |
| tmp_5_26520691_G_T | 90 | S>I | No | 1000Genomes | |
| ENSVATH14651208 | 93 | D>E | No | 1000Genomes | |
| tmp_5_26520754_A_T | 111 | K>M | No | 1000Genomes | |
| ENSVATH12952436 | 131 | V>L | No | 1000Genomes | |
| ENSVATH03483574 | 158 | V>L | No | 1000Genomes | |
| tmp_5_26521182_G_A | 166 | A>T | No | 1000Genomes | |
| ENSVATH12952437 | 186 | K>N | No | 1000Genomes | |
| tmp_5_26521361_G_C | 199 | E>Q | No | 1000Genomes | |
| ENSVATH12952439 | 214 | S>G | No | 1000Genomes | |
| tmp_5_26521416_G_A | 217 | R>Q | No | 1000Genomes | |
| tmp_5_26521434_C_T | 223 | A>V | No | 1000Genomes |
No associated diseases with Q8LCV1
1 regional properties for Q8LCV1
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | GPCR, rhodopsin-like, 7TM | 74 - 332 | IPR017452 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| microtubule | Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| beta-tubulin binding | Binding to the microtubule constituent protein beta-tubulin. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| cortical microtubule organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cell cortex, i.e. just beneath the plasma membrane of a cell. |
| cytokinesis by cell plate formation | The process of dividing the cytoplasm of a parent cell where a structure forms in the cytoplasm and grows until reaching the plasma membrane, thereby completely separating the cytoplasms of adjacent progeny cells. An example of this is found in Arabidopsis thaliana. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q11183 | txdc-9 | Thioredoxin domain-containing protein 9 | Caenorhabditis elegans | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MDPDTVKSTL | SNLAFGNVLA | AAARDYKKEV | LANEKAQGSR | PVNEEVDLDE | LMDDPELEKL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| HADRIAALRR | EVEKREAFKR | QGHGEYREVS | EGDFLGEVTR | SEKVICHFYH | KEFYRCKIMD |
| 130 | 140 | 150 | 160 | 170 | 180 |
| KHLKTLAPRH | VDTKFIKMDA | ENAPFFVTKL | AIKTLPCVIL | FSKGIAMDRL | VGFQDLGAKD |
| 190 | 200 | 210 | 220 | ||
| DFSTTKLENL | LVKKGMLSEK | RKEEDEEDYE | YQESIRRSVR | SSANVDSDSD |