Q8L7W8
PR
Gene name |
FUC95A (AXY8, At4g34260, F10M10.30) |
Protein name |
Alpha-L-fucosidase 2 |
Names |
Alpha-1,2-fucosidase 2, Alpha-L-fucosidase 95A, AtFuc95A, Alpha-L-fucoside fucohydrolase 2, Protein ALTERED XYLOGLUCAN 8 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT4G34260 |
EC number |
3.2.1.51: Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8L7W8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8L7W8-F1 | Predicted | AlphaFoldDB |
60 variants for Q8L7W8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_4_16398141_G_T | 4 | K>N | No | 1000Genomes | |
| ENSVATH06822586 | 22 | I>R | No | 1000Genomes | |
| ENSVATH06822587 | 41 | A>S | No | 1000Genomes | |
| ENSVATH12385436 | 51 | P>S | No | 1000Genomes | |
| tmp_4_16398359_C_T | 77 | T>M | No | 1000Genomes | |
| tmp_4_16398370_G_A | 81 | G>S | No | 1000Genomes | |
| tmp_4_16398380_C_A | 84 | S>Y | No | 1000Genomes | |
| ENSVATH14335167 | 120 | E>K | No | 1000Genomes | |
| ENSVATH06822593 | 183 | V>M | No | 1000Genomes | |
| ENSVATH12385441 | 184 | D>N | No | 1000Genomes | |
| ENSVATH00551936 | 191 | A>S | No | 1000Genomes | |
| ENSVATH00551937 | 199 | I>V | No | 1000Genomes | |
| tmp_4_16399134_T_A | 212 | F>L | No | 1000Genomes | |
| tmp_4_16399136_A_G | 213 | K>R | No | 1000Genomes | |
| ENSVATH00551938 | 219 | E>K | No | 1000Genomes | |
| tmp_4_16399166_A_G | 223 | H>R | No | 1000Genomes | |
| tmp_4_16399250_G_A | 251 | S>N | No | 1000Genomes | |
| tmp_4_16399271_C_T | 258 | P>L | No | 1000Genomes | |
| ENSVATH06822597 | 278 | G>S | No | 1000Genomes | |
| tmp_4_16399387_G_A | 297 | A>T | No | 1000Genomes | |
| ENSVATH00551941 | 302 | A>S | No | 1000Genomes | |
| tmp_4_16399453_A_G | 319 | I>V | No | 1000Genomes | |
| ENSVATH12385442 | 322 | A>T | No | 1000Genomes | |
| ENSVATH12385443 | 324 | E>D | No | 1000Genomes | |
| tmp_4_16399510_T_C | 338 | S>P | No | 1000Genomes | |
| tmp_4_16399525_C_T | 343 | R>C | No | 1000Genomes | |
| tmp_4_16399538_A_G | 347 | D>G | No | 1000Genomes | |
| tmp_4_16399597_A_C | 367 | T>P | No | 1000Genomes | |
| tmp_4_16399630_G_T | 378 | V>L | No | 1000Genomes | |
| tmp_4_16399654_G_A | 386 | D>N | No | 1000Genomes | |
| tmp_4_16399720_G_A | 408 | G>R | No | 1000Genomes | |
| ENSVATH06822599 | 420 | R>T | No | 1000Genomes | |
| tmp_4_16399896_A_G | 438 | M>V | No | 1000Genomes | |
| tmp_4_16399912_C_G | 443 | S>C | No | 1000Genomes | |
| tmp_4_16399949_G_T | 455 | L>F | No | 1000Genomes | |
| tmp_4_16399960_T_C | 459 | M>T | No | 1000Genomes | |
| ENSVATH06822602 | 465 | N>K | No | 1000Genomes | |
| ENSVATH00551943 | 487 | I>V | No | 1000Genomes | |
| ENSVATH06822603 | 518 | Y>F | No | 1000Genomes | |
| tmp_4_16400357_G_C | 529 | K>N | No | 1000Genomes | |
| tmp_4_16400394_C_A | 542 | L>I | No | 1000Genomes | |
| ENSVATH06822605 | 554 | L>F | No | 1000Genomes | |
| ENSVATH06822606 | 602 | G>E | No | 1000Genomes | |
| ENSVATH14335171 | 606 | D>E | No | 1000Genomes | |
| ENSVATH06822607 | 613 | I>F | No | 1000Genomes | |
| ENSVATH00551949 | 631 | R>M | No | 1000Genomes | |
| ENSVATH12385468 | 652 | G>A | No | 1000Genomes | |
| tmp_4_16401101_G_A | 720 | R>H | No | 1000Genomes | |
| tmp_4_16401312_A_C | 751 | E>D | No | 1000Genomes | |
| ENSVATH06822610 | 769 | A>E | No | 1000Genomes | |
| ENSVATH06822611 | 770 | D>G | No | 1000Genomes | |
| ENSVATH00551952 | 778 | N>K | No | 1000Genomes | |
| tmp_4_16401402_G_T | 781 | R>S | No | 1000Genomes | |
| tmp_4_16401403_G_T | 782 | A>S | No | 1000Genomes | |
| tmp_4_16401479_T_A | 807 | I>N | No | 1000Genomes | |
| ENSVATH00551953 | 808 | V>I | No | 1000Genomes | |
| tmp_4_16401509_T_A | 817 | I>N | No | 1000Genomes | |
| ENSVATH14335173 | 825 | P>S | No | 1000Genomes | |
| ENSVATH14335174 | 826 | G>E | No | 1000Genomes | |
| ENSVATH00551955 | 841 | D>E | No | 1000Genomes |
No associated diseases with Q8L7W8
1 regional properties for Q8L7W8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Glycosyl hydrolase family 95, N-terminal domain | 54 - 309 | IPR027414 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.2.1.51 | Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| apoplast | The cell membranes and intracellular regions in a plant are connected through plasmodesmata, and plants may be described as having two major compartments: the living symplast and the non-living apoplast. The apoplast is external to the plasma membrane and includes cell walls, intercellular spaces and the lumen of dead structures such as xylem vessels. Water and solutes pass freely through it. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| 1,2-alpha-L-fucosidase activity | Catalysis of the reaction: H2O + methyl-2-alpha-L-fucopyranosyl-beta-D-galactoside = L-fucose + methyl beta-D-galactoside. |
| alpha-L-fucosidase activity | Catalysis of the reaction: an alpha-L-fucoside + H2O = an alcohol + L-fucose. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| carbohydrate metabolic process | The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAEKSSFFVH | FSCLLLLLTI | IITCGEGVRN | PVRPRSSERR | ALMDGQDLSR | PLKLTFGGPS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| RNWTDAIPIG | NGRLGATIWG | GVSSEILNIN | EDTIWTGVPA | DYTNQKAPEA | LAEVRRLVDE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| RNYAEATSEA | VKLSGQPSDV | YQIVGDLNLE | FDSSHRKYTQ | ASYRRELDLE | TAVAKVSYSV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GAVDFSREFF | ASNPDQVIIA | KIYASKPGSL | SFKVSFDSEL | HHHSETNPKA | NQILMRGSCR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| PKRLPVNLKK | SINATNIPYD | DHKGLQFASI | LEVRVSNGGS | VSSLGGKKLS | VEKADWAVLL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LAASSNFDGP | FTMPVDSKID | PAKECVNRIS | SVQKYSYSDL | YARHLGDYQK | LFNRVSLHLS |
| 370 | 380 | 390 | 400 | 410 | 420 |
| GSSTNETVQQ | ATSTAERVRS | FKTDQDPSLV | ELLFQYGRYL | LISSSRPGTQ | VANLQGIWNR |
| 430 | 440 | 450 | 460 | 470 | 480 |
| DIQPPWDGAP | HLNINLQMNY | WHSLPGNIRE | CQEPLFDYMS | ALAINGRKTA | QVNYGASGWV |
| 490 | 500 | 510 | 520 | 530 | 540 |
| AHQVSDIWAK | TSPDRGEAVW | ALWPMGGAWL | CTHAWEHYTY | TMDKEFLKKK | GYPLLEGCTS |
| 550 | 560 | 570 | 580 | 590 | 600 |
| FLLDWLIKGK | DGFLQTNPST | SPEHMFTAPI | GKPASVSYSS | TMDIAIIKEV | FADIVSASEI |
| 610 | 620 | 630 | 640 | 650 | 660 |
| LGKTNDTLIG | KVIAAQAKLP | PTRISKDGSI | REWAEDFEDP | EVHHRHVSHL | FGLFPGHTIT |
| 670 | 680 | 690 | 700 | 710 | 720 |
| VEKSPELAKA | VEATLKKRGE | EGPGWSTTWK | AALWARLHNS | EHAYRMVTHI | FDLVDPLNER |
| 730 | 740 | 750 | 760 | 770 | 780 |
| NYEGGLYSNM | FTAHPPFQID | ANFGFAAAVA | EMLVQSTTKD | LYLLPALPAD | KWPNGIVNGL |
| 790 | 800 | 810 | 820 | 830 | 840 |
| RARGGVTVSI | KWMEGNLVEF | GLWSEQIVST | RIVYRGISAA | AELLPGKVFT | FDKDLRCIRT |
| DKL |