Q8L7E9
Gene name |
MCA1 (At4g35920, T19K4.50) |
Protein name |
Protein MID1-COMPLEMENTING ACTIVITY 1 |
Names |
|
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT4G35920 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8L7E9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8L7E9-F1 | Predicted | AlphaFoldDB |
19 variants for Q8L7E9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_4_17013903_T_G | 97 | Y>S | No | 1000Genomes | |
| tmp_4_17013793_C_A | 134 | A>S | No | 1000Genomes | |
| tmp_4_17013684_T_C | 144 | D>G | No | 1000Genomes | |
| tmp_4_17013634_C_T | 161 | D>N | No | 1000Genomes | |
| tmp_4_17013498_C_T | 206 | R>Q | No | 1000Genomes | |
| tmp_4_17013460_T_G | 219 | I>L | No | 1000Genomes | |
| ENSVATH06831671 | 234 | P>L | No | 1000Genomes | |
| ENSVATH06831670 | 246 | K>Q | No | 1000Genomes | |
| ENSVATH06831669 | 248 | S>T | No | 1000Genomes | |
| tmp_4_17013349_T_G | 256 | T>P | No | 1000Genomes | |
| ENSVATH06831668 | 263 | D>N | No | 1000Genomes | |
| tmp_4_17013303_C_T | 271 | R>H | No | 1000Genomes | |
| tmp_4_17013300_G_A | 272 | A>V | No | 1000Genomes | |
| ENSVATH00554259 | 310 | E>D | No | 1000Genomes | |
| tmp_4_17012871_G_C | 315 | F>L | No | 1000Genomes | |
| ENSVATH12419258 | 318 | F>L | No | 1000Genomes | |
| ENSVATH14342943 | 334 | N>S | No | 1000Genomes | |
| tmp_4_17012606_T_C | 368 | K>R | No | 1000Genomes | |
| ENSVATH14342939 | 396 | R>K | No | 1000Genomes |
No associated diseases with Q8L7E9
1 regional properties for Q8L7E9
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | MCAfunc domain | 25 - 167 | IPR045766 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of plasma membrane | The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| calcium channel activity | Enables the facilitated diffusion of a calcium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. |
5 GO annotations of biological process
| Name | Definition |
|---|---|
| calcium ion transport | The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
| carbohydrate homeostasis | A homeostatic process involved in the maintenance of an internal steady state of a carbohydrate within an organism or cell. |
| cell surface receptor signaling pathway | The series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription. |
| cellular response to mechanical stimulus | Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus. |
| osmosensory signaling pathway | The series of molecular signals initiated in response to osmotic change. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| B6SJQ0 | CNR13 | Cell number regulator 13 | Zea mays (Maize) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSHSWDGLGE | IASVAQLTGL | DAVKLIGLIV | KAANTAWMHK | KNCRQFAQHL | KLIGNLLEQL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| KISEMKKYPE | TREPLEGLED | ALRRSYLLVN | SCRDRSYLYL | LAMGWNIVYQ | FRKHQDEIDR |
| 130 | 140 | 150 | 160 | 170 | 180 |
| FLKIIPLITL | VDNARIRERF | EYIDRDQREY | TLDEEDRHVQ | DVILKQESTR | EAASVLKKTL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SCSYPNLRFC | EALKTENEKL | QIELQRSQEH | YDVAQCEVIQ | RLIGVTQAAA | AVEPDSEKEL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| TKKASKKSER | SSSMKTEYSY | DEDSPKKSST | RAASRSTSNV | SSGHDLLSRR | ASQAQHHEEW |
| 310 | 320 | 330 | 340 | 350 | 360 |
| HTDLLACCSE | PSLCFKTFFF | PCGTLAKIAT | AASNRHISSA | EACNELMAYS | LILSCCCYTC |
| 370 | 380 | 390 | 400 | 410 | 420 |
| CVRRKLRKTL | NITGGFIDDF | LSHVMCCCCA | LVQELREVEI | RGAYGTEKTK | ISPPSSQFME |
| H |