AiPD: Autoinhibited Protein Database

Gene name	EMF2 (At5g51230/At5g51240, MWD22.18/MWD22.19)
Protein name	Polycomb group protein EMBRYONIC FLOWER 2
Names
Species	Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway	ath:AT5G51230
EC number
Protein Class

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

359-457 (Predicted disordered autoinhibitory region) PR

359-457 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q8L6Y4-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
tmp_5_20824166_C_G	5	P>R	No	1000Genomes
ENSVATH07394126	12	S>T	No	1000Genomes
ENSVATH07394128	56	Q>H	No	1000Genomes
ENSVATH03408220	82	I>L	No	1000Genomes
tmp_5_20824967_G_C	94	A>P	No	1000Genomes
tmp_5_20824968_C_T	94	A>V	No	1000Genomes
tmp_5_20825178_C_G	132	L>V	No	1000Genomes
tmp_5_20825196_G_A	138	V>I	No	1000Genomes
ENSVATH12697078	158	L>W	No	1000Genomes
tmp_5_20825400_C_T	175	A>V	No	1000Genomes
ENSVATH07394141	224	T>K	No	1000Genomes
ENSVATH07394153	286	N>D	No	1000Genomes
tmp_5_20826236_G_A	287	D>N	No	1000Genomes
tmp_5_20826709_T_G	331	V>G	No	1000Genomes
ENSVATH00726230	346	T>N	No	1000Genomes
ENSVATH07394161	349	L>V	No	1000Genomes
ENSVATH07394164	375	K>N	No	1000Genomes
tmp_5_20827472_G_A	382	D>N	No	1000Genomes
ENSVATH07394175	396	R>K	No	1000Genomes
ENSVATH12697177	405	R>W	No	1000Genomes
tmp_5_20827627_A_G	406	S>G	No	1000Genomes
ENSVATH03408242	438	P>T	No	1000Genomes
tmp_5_20827902_T_A	442	Y>N	No	1000Genomes
tmp_5_20827975_G_C	466	C>S	No	1000Genomes
ENSVATH12697183	536	A>V	No	1000Genomes
tmp_5_20829099_G_A	581	E>K	No	1000Genomes
ENSVATH12697227	611	H>Q	No	1000Genomes
ENSVATH07394193	630	Q>E	No	1000Genomes

Type	Name	Position	InterPro Accession
domain	Polycomb protein, VEFS-Box	490 - 624	IPR019135

		Description
EC Number
Subcellular Localization	Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
nucleus	A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

Name	Definition
chromatin DNA binding	Binding to DNA that is assembled into chromatin.
DNA binding	Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA-binding transcription factor activity	A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
metal ion binding	Binding to a metal ion.
transcription cis-regulatory region binding	Binding to a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.

Name	Definition
cell differentiation	The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
flower development	The process whose specific outcome is the progression of the flower over time, from its formation to the mature structure. The flower is the reproductive structure in a plant, and its development begins with the transition of the vegetative or inflorescence meristem into a floral meristem.
negative regulation of flower development	Any process that stops, prevents, or reduces the frequency, rate or extent of flower development.
regulation of gene expression by genomic imprinting	An epigenetic mechanism of regulation of gene expression in which epigenetic modifications (imprints) are established during gametogenesis. For a given gene to show parentally biased expression, the imprint are established exclusively in one of the two parental genomes, thus generating an asymmetry between the maternal and paternal alleles.

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
No homologous proteins