Q8L611
Gene name |
SEC31B |
Protein name |
Protein transport protein SEC31 homolog B |
Names |
SEC31-like protein B |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT3G63460 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8L611
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8L611-F1 | Predicted | AlphaFoldDB |
53 variants for Q8L611
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH14473903 | 4 | I>L | No | 1000Genomes | |
| ENSVATH14473902 | 7 | V>G | No | 1000Genomes | |
| ENSVATH14473901 | 14 | A>S | No | 1000Genomes | |
| ENSVATH06365403 | 73 | G>E | No | 1000Genomes | |
| tmp_3_23436926_C_T | 106 | G>S | No | 1000Genomes | |
| tmp_3_23436728_T_C | 122 | K>R | No | 1000Genomes | |
| ENSVATH06365397 | 171 | T>S | No | 1000Genomes | |
| ENSVATH06365396 | 191 | T>A | No | 1000Genomes | |
| tmp_3_23435303_T_C | 333 | I>V | No | 1000Genomes | |
| tmp_3_23435296_T_C | 335 | N>S | No | 1000Genomes | |
| tmp_3_23434976_C_T | 341 | R>H | No | 1000Genomes | |
| ENSVATH06365379 | 348 | N>T | No | 1000Genomes | |
| ENSVATH06365378 | 350 | G>S | No | 1000Genomes | |
| tmp_3_23434792_G_A | 363 | P>L | No | 1000Genomes | |
| tmp_3_23434711_A_T | 390 | L>Q | No | 1000Genomes | |
| ENSVATH12898842 | 437 | E>K | No | 1000Genomes | |
| ENSVATH06365370 | 474 | D>N | No | 1000Genomes | |
| ENSVATH12898841 | 491 | D>V | No | 1000Genomes | |
| ENSVATH02539732 | 493 | A>V | No | 1000Genomes | |
| ENSVATH06365369 | 494 | A>P | No | 1000Genomes | |
| tmp_3_23434216_A_C | 495 | D>E | No | 1000Genomes | |
| tmp_3_23434113_T_C | 530 | T>A | No | 1000Genomes | |
| tmp_3_23434091_G_A | 537 | P>L | No | 1000Genomes | |
| tmp_3_23434073_G_T | 543 | S>Y | No | 1000Genomes | |
| ENSVATH14473898 | 552 | M>T | No | 1000Genomes | |
| ENSVATH12898840 | 600 | G>D | No | 1000Genomes | |
| tmp_3_23433721_G_A | 626 | A>V | No | 1000Genomes | |
| ENSVATH00803250 | 629 | N>S | No | 1000Genomes | |
| tmp_3_23432983_G_A | 749 | A>V | No | 1000Genomes | |
| tmp_3_23432911_A_T | 773 | L>H | No | 1000Genomes | |
| tmp_3_23432879_C_G | 784 | A>P | No | 1000Genomes | |
| tmp_3_23432786_T_A | 789 | N>I | No | 1000Genomes | |
| ENSVATH06365356 | 796 | T>I | No | 1000Genomes | |
| tmp_3_23432757_G_C | 799 | Q>E | No | 1000Genomes | |
| tmp_3_23432504_T_A,G | 852 | Q>L | No | 1000Genomes | |
| tmp_3_23432504_T_A,G | 852 | Q>P | No | 1000Genomes | |
| ENSVATH00803246 | 866 | T>A | No | 1000Genomes | |
| ENSVATH06365347 | 869 | A>P | No | 1000Genomes | |
| tmp_3_23431963_C_T | 873 | M>I | No | 1000Genomes | |
| tmp_3_23431956_T_C | 876 | T>A | No | 1000Genomes | |
| tmp_3_23431931_G_A | 884 | A>V | No | 1000Genomes | |
| ENSVATH14473864 | 889 | D>N | No | 1000Genomes | |
| ENSVATH12898798 | 895 | T>I | No | 1000Genomes | |
| tmp_3_23431790_G_T | 904 | P>Q | No | 1000Genomes | |
| ENSVATH12898796 | 920 | P>H | No | 1000Genomes | |
| ENSVATH06365343 | 929 | Y>S | No | 1000Genomes | |
| ENSVATH06365342 | 934 | M>I | No | 1000Genomes | |
| tmp_3_23431677_C_T | 942 | A>T | No | 1000Genomes | |
| tmp_3_23431676_G_A | 942 | A>V | No | 1000Genomes | |
| tmp_3_23431659_T_C | 948 | T>A | No | 1000Genomes | |
| tmp_3_23431608_G_T | 965 | P>T | No | 1000Genomes | |
| tmp_3_23431578_C_A | 975 | A>S | No | 1000Genomes | |
| tmp_3_23431529_G_A | 991 | S>F | No | 1000Genomes |
No associated diseases with Q8L611
No regional properties for Q8L611
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q8L611 | |||
5 GO annotations of cellular component
| Name | Definition |
|---|---|
| COPII vesicle coat | One of two multimeric complexes that forms a membrane vesicle coat. COPII is best characterized in S. cerevisiae, where the subunits are called Sar1p, Sec13p, Sec31p, Sec23p, and Sec24p. Vesicles with COPII coats are found associated with endoplasmic reticulum (ER) membranes at steady state. |
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| endoplasmic reticulum exit site | An endoplasmic reticulum part at which COPII-coated vesicles are produced. |
| Golgi apparatus | A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. |
| plasmodesma | A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| structural molecule activity | The action of a molecule that contributes to the structural integrity of a complex or its assembly within or outside a cell. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| COPII-coated vesicle cargo loading | The formation of a macromolecular complex between the COPII coat proteins and proteins and/or lipoproteins that are going to be transported by the COPII vesicle to the Golgi. |
| endoplasmic reticulum organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum. |
| intracellular protein transport | The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MACIKGVGRS | ASVALAPDAP | YMAAGTMAGA | VDLSFSSSAN | LEIFKLDFQS | DDRDLPLVGE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| IPSSERFNRL | AWGRNGSGSE | EFALGLIAGG | LVDGNIDLWN | PLSLIGSQPS | ENALVGHLSV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| HKGPVRGLEF | NAISSNLLAS | GADDGEICIW | DLLKPSEPSH | FPLLKGSGSA | TQGEISFISW |
| 190 | 200 | 210 | 220 | 230 | 240 |
| NRKVQQILAS | TSYNGTTVIW | DLRKQKPIIN | FADSVRRRCS | VLQWNPNVTT | QIMVASDDDS |
| 250 | 260 | 270 | 280 | 290 | 300 |
| SPTLKLWDMR | NIMSPVREFT | GHQRGVIAME | WCPSDSSYLL | TCAKDNRTIC | WDTNTAEIVA |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ELPAGNNWNF | DVHWYPKIPG | VISASSFDGK | IGIYNIEGCS | RYGVEENNFG | TAPLKAPKWY |
| 370 | 380 | 390 | 400 | 410 | 420 |
| KRPVGASFGF | GGKLVSCHAR | APAKGTSSIL | SEVFLHSLVT | EQSLVSRTSE | FEAAIENGDM |
| 430 | 440 | 450 | 460 | 470 | 480 |
| TSLRGLCEKK | SEETESEEEK | ETWGLLKIMF | EEEGTSRTKL | ISHLGFTLPV | AEKDQAVDGL |
| 490 | 500 | 510 | 520 | 530 | 540 |
| SSDLNGIRLE | DTAADALDLD | DSNEAAAFAM | DNGEDFFNNF | PAKPDTPVST | SAKDFMPSDT |
| 550 | 560 | 570 | 580 | 590 | 600 |
| DFSTKGEETQ | EMQEEEEESS | DPVFDNAIQR | ALIVGDYKEA | VDQCITANKM | ADALVIAHVG |
| 610 | 620 | 630 | 640 | 650 | 660 |
| GTALWESTRE | KYLKTSSAPY | MKVVSAMVNN | DLRSLIYTRS | HKFWKETLAL | LCTFAQGEQW |
| 670 | 680 | 690 | 700 | 710 | 720 |
| TTLCDALASK | LMAAGNTLAA | VLCYICAGNV | DRTVEIWSRS | LANERDGRSY | AELLQDLMEK |
| 730 | 740 | 750 | 760 | 770 | 780 |
| TLVLALATGN | KKFSASLCKL | FESYAEILAS | QGLLTTAMKY | LKVLDSGGLS | PELSILRDRI |
| 790 | 800 | 810 | 820 | 830 | 840 |
| SLSAEPETNT | TASGNTQPQS | TMPYNQEPTQ | AQPNVLANPY | DNQYQQPYTD | SYYVPQVSHP |
| 850 | 860 | 870 | 880 | 890 | 900 |
| PMQQPTMFMP | HQAQPAPQPS | FTPAPTSNAQ | PSMRTTFVPS | TPPALKNADQ | YQQPTMSSHS |
| 910 | 920 | 930 | 940 | 950 | 960 |
| FTGPSNNAYP | VPPGPGQYAP | SGPSQLGQYP | NPKMPQVVAP | AAGPIGFTPM | ATPGVAPRSV |
| 970 | 980 | 990 | 1000 | 1010 | 1020 |
| QPASPPTQQA | AAQAAPAPAT | PPPTVQTADT | SNVPAHQKPV | IATLTRLFNE | TSEALGGARA |
| 1030 | 1040 | 1050 | 1060 | 1070 | 1080 |
| NTTKKREIED | NSRKLGALFV | KLNSGDISKN | AADKLAQLCQ | ALDNNDFSTA | LQIQVLLTTS |
| 1090 | 1100 | ||||
| EWDECNFWLA | TLKRMMVKAR | QNVR |