Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q8KGE7

Entry ID Method Resolution Chain Position Source
AF-Q8KGE7-F1 Predicted AlphaFoldDB

No variants for Q8KGE7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8KGE7

No associated diseases with Q8KGE7

3 regional properties for Q8KGE7

Type Name Position InterPro Accession
domain ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain 131 - 349 IPR000194
domain ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain 9 - 74 IPR004100
active_site ATPase, alpha/beta subunit, nucleotide-binding domain, active site 340 - 349 IPR020003

Functions

Description
EC Number
Subcellular Localization
  • Cell inner membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
proton-transporting ATP synthase complex, coupling factor F(o) All non-F1 subunits of a hydrogen-transporting ATP synthase, including integral and peripheral membrane proteins.

1 GO annotations of molecular function

Name Definition
proton-transporting ATP synthase activity, rotational mechanism Enables the synthesis of ATP from ADP and phosphate by the transfer of protons from one side of a membrane to the other by a rotational mechanism driven by a gradient according to the reaction: ADP + H2O + phosphate + H+(in) -> ATP + H+(out).

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRKKAISRIL ALVVPVLLSL NSQAFATSVQ DESPVTGSAV EAVHTVPSTV AAPVAGHAEA
70 80 90 100 110 120
AAGQAAKAEE KPGDLIMHHI LDNSTFSFEP FGEVHLPHLE VAGFDISITK HVVMIWLAAI
130 140 150 160 170 180
LLVVIASAAG ASVKKMSANQ APKGVANVFE SLVDFISNDV AKPNIGHGYE KFLPYLLTVF
190 200 210 220 230 240
FFILVCNLLG LIPYGATATG NINVTLTLSV FTFVITQFSA FKAQGVKGYL QHLTAGTHWA
250 260 270 280 290 300
LWIIMVPIEI LGQFTKPFAL TIRLFANMTA GHIIILSLFF ISFILKSYIV AVAVSIPFAI
310 320 330 340 350
FIYLLELFVA FLQAYVFTML SALFIGLATA HSDSHDGHEL EATARHGDGL TV