Q8KCC0

PR
Gene name
mutS
Protein name
DNA mismatch repair protein MutS
Names
Species
Chlorobaculum tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS) (Chlorobium tepidum)
KEGG Pathway
cte:CT1503
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

789-859 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8KCC0

Entry ID Method Resolution Chain Position Source
AF-Q8KCC0-F1 Predicted AlphaFoldDB

No variants for Q8KCC0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8KCC0

No associated diseases with Q8KCC0

5 regional properties for Q8KCC0

Type Name Position InterPro Accession
domain DNA mismatch repair protein MutS, C-terminal 623 - 812 IPR000432
domain DNA mismatch repair protein MutS-like, N-terminal 13 - 124 IPR007695
domain DNA mismatch repair protein MutS, core 282 - 605 IPR007696
domain DNA mismatch repair protein MutS, connector domain 133 - 262 IPR007860
domain DNA mismatch repair protein MutS, clamp 442 - 532 IPR007861

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP-dependent DNA damage sensor activity A molecule that recognises toxic DNA structures, and initiates a signalling response, driven by ATP hydrolysis.
damaged DNA binding Binding to damaged DNA.
mismatched DNA binding Binding to a double-stranded DNA region containing one or more mismatches.

1 GO annotations of biological process

Name Definition
mismatch repair A system for the correction of errors in which an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAKSAQGRTK EPTPMMRQYL EVKERYPGYL LLFRVGDFYE TFLDDAVTVS SALNIVLTRR
70 80 90 100 110 120
SNGGAGEIPL AGFPHHASEG YIAKLVTKGF KVAVCDQVED PALAKGIVKR EITDIVTPGI
130 140 150 160 170 180
TYSDKILDDR HNNYLCAVAP VKRGREHMAG VAFVDVTTAE FRMTELPLGE LKDFLQSLRP
190 200 210 220 230 240
SEILISSRDK ELRESLAKSL FSGALFTTLD EWMFTEEQAA RVLENHFKTH SLKGFGIEGY
250 260 270 280 290 300
EAGRIAAGVI LQYLEEAKQG SLKYLVRIGL VESGETMTLD IQTCRNLEII SSMQDGSLNG
310 320 330 340 350 360
SLLEVIDRTK NPMGARLLRR WLLHPLRKLE PVVRRHDAVG ELLDAPEMRE GIRGMLGGII
370 380 390 400 410 420
DLERALARIA TSRAMPREVR QLGSSLAMIP QLKSLLEGSK SLRLRELALR LDPLPELAET
430 440 450 460 470 480
IEKALDAEAS GTLRDGGYIR AGYHAELDEL RAISSGARDR LLEIQQQERQ RTSISTLKVQ
490 500 510 520 530 540
YNKVFGYYIE VSRANSDKVP EYYEKKQTLV NAERYTIPAL KEYEEKILTA EEKSQLLEHQ
550 560 570 580 590 600
LFQELCAMIA EQAASIQTTA AALAELDCLA CFASCADEFG YCRPVMNEGT ELSIRAGRHP
610 620 630 640 650 660
VLERILGADE PYVANDCQVG SEQQLLIITG PNMAGKSSYL RQVGLVVLLA QVGCFVPAES
670 680 690 700 710 720
AEIGLVDRIF TRVGASDNLT SGESTFLVEM NEAASILNNA TERSLLLLDE IGRGTSTFDG
730 740 750 760 770 780
MSIAWSMCEY IHDQLRSRTL FATHYHELAE LESRFERIVN FNATVVETAD TVIFLRKIVR
790 800 810 820 830 840
GASDNSYGIE VAKMAGMPPE VIERAREILA GMERREVEVP VQRQALPLRV ESRQISLFEE
850 860 870
EESRLRKALS GIDINRLTPL DALMELKRLQ EIALGKGA