Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q8KAF0

Entry ID Method Resolution Chain Position Source
AF-Q8KAF0-F1 Predicted AlphaFoldDB

No variants for Q8KAF0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8KAF0

No associated diseases with Q8KAF0

4 regional properties for Q8KAF0

Type Name Position InterPro Accession
domain GTP binding domain 162 - 294 IPR006073
conserved_site GTP1/OBG, conserved site 213 - 226 IPR006074
domain GTP1/OBG domain 1 - 159 IPR006169
domain OBG-type guanine nucleotide-binding (G) domain 160 - 343 IPR031167

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
magnesium ion binding Binding to a magnesium (Mg) ion.

1 GO annotations of biological process

Name Definition
ribosome biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKFVDSAKIS VKAGDGGRGC VSFRREKFVP KGGPDGGDGG RGGHVYLRAN KQLTTLLDFK
70 80 90 100 110 120
YRKSYIAGRG GHGLGARKSG KDGKDVIIGV PCGTVVRNVE TGEVICDMVE DGQEIMIAKG
130 140 150 160 170 180
GRGGWGNQHF ATATRQAPRF AQPGEPGEEY ELEMELKLMA DVGLVGFPNA GKSTLISVLS
190 200 210 220 230 240
AARPKIADYP FTTLVPNLGI VRYEDYKSFV MADIPGIIEG AAEGRGLGIQ FLRHIERTKT
250 260 270 280 290 300
LLIMVPSNTE DIAAEYATLL KELEKFDPSL LSKPRLVVIT KMDIAPEDFT MPELEKGVKV
310 320 330
LAISSVAGQG LKALKDELWR QVSLQNQSPS EHAGS