Q8K385

PR
Gene name
FRRS1 (Sdfr2, Sdr2)
Protein name
Ferric-chelate reductase 1
Names
Stromal cell-derived receptor 2, SDR-2
Species
Mus musculus (Mouse)
KEGG Pathway
mmu:20321
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

4-218 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8K385

Entry ID Method Resolution Chain Position Source
AF-Q8K385-F1 Predicted AlphaFoldDB

No variants for Q8K385

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8K385

No associated diseases with Q8K385

3 regional properties for Q8K385

Type Name Position InterPro Accession
domain Reeler domain 13 - 179 IPR002861
domain DOMON domain 216 - 331 IPR005018
domain Cytochrome b561/ferric reductase transmembrane 335 - 534 IPR006593

Functions

Description
EC Number
Subcellular Localization
  • Membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

2 GO annotations of molecular function

Name Definition
metal ion binding Binding to a metal ion.
oxidoreductase activity, acting on metal ions Catalysis of an oxidation-reduction in which the oxidation state of metal ion is altered.

1 GO annotations of biological process

Name Definition
cellular iron ion homeostasis Any process involved in the maintenance of an internal steady state of iron ions at the level of a cell.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAAPQITLSV LVIALLTCSV TAYPNGKVPM SCGGMIPQHN HSPQSEPIHQ ITVSQTTFKP
70 80 90 100 110 120
GDQIEVTLSG PPFRGFLLEA RDAENLSGPP IGSFTLIDSE ESQLLTCTDV QGLAVSHTRS
130 140 150 160 170 180
SKKTEIKVYW DAPSPAPDHI RFLATVVQKF KIYWVKIPSP VISQPNAPPF TTPKATTQPL
190 200 210 220 230 240
TTPPSVSHLT KPFSAFECGN KKFCVRSPLN CDPEKEPACV FLSFTRDNQS VMVEMSGPSD
250 260 270 280 290 300
GYVSFAFSHD QWMGDDDAYL CIREDQTVDI QPSYLTGRSY PVMDSRGTLE DMAWRLADGV
310 320 330 340 350 360
IQCSFRRNIT LPEAKNRFVL NESYYIFFAE GPSHDGRIFR HSQQPLITYE KYNVTDTPKS
370 380 390 400 410 420
VGGSRSSPLL KAHGALMFVA WMTTVSIGVL VARFFRSVWS KAFFLREAAW FQVHRMLMVA
430 440 450 460 470 480
TSLLTCVAFV LPFVYRGGWS WRAGYHPYLG CTVMTLAVLQ PLLATFRPPL HDPRRQVFNW
490 500 510 520 530 540
THWSVGTAAR IIAVAAMFLG MDLPGLNLPS PQKTYAMMGF VVWHIGTEVI LEIHAYRLSR
550 560 570 580 590
KVEILDNDRI QILQSLTVAE AEGHVFKKVV LAVYICGNVI FLSIFLSAIN HI