AiPD: Autoinhibited Protein Database

Gene name	Champ1 (D8Ertd457e, Kiaa1802, Zfp828, Znf828)
Protein name	Chromosome alignment-maintaining phosphoprotein 1
Names	Zinc finger protein 828
Species	Mus musculus (Mouse)
KEGG Pathway	mmu:101994
EC number
Protein Class

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

195-344 (Predicted disordered autoinhibitory region) PR

195-344 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q8K327-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
rs3388926319	14	L>M	No	EVA
rs215151891	20	S>N	No	EVA
rs3388977089	27	E>*	No	EVA
rs226572569	31	L>I	No	EVA
rs3388974958	47	G>W	No	EVA
rs3388959264	59	A>E	No	EVA
rs3388959281	67	C>*	No	EVA
rs3388965931	72	K>Q	No	EVA
rs29987986	101	K>R	No	EVA
rs233282363	112	P>A	No	EVA
rs250971723	114	R>Q	No	EVA
rs220352547	133	E>G	No	EVA
rs243651583	134	A>T	No	EVA
rs3388965957	143	P>A	No	EVA
rs29987989	146	Q>K	No	EVA
rs3388972505	146	Q>L	No	EVA
rs251543536	149	G>V	No	EVA
rs228220978	157	G>S	No	EVA
rs240584954	159	G>A	No	EVA
rs3388948590	169	P>H	No	EVA
rs228052694	170	C>S	No	EVA
rs250701227	182	P>S	No	EVA
rs213048322	186	R>C	No	EVA
rs3388968696	197	E>D	No	EVA
rs3388975018	203	P>H	No	EVA
rs216455322	229	A>P	No	EVA
rs29989018	244	P>T	No	EVA
rs250913460	271	P>L	No	EVA
rs3388942859	273	P>L	No	EVA
rs3388974936	307	P>H	No	EVA
rs3388977107	307	P>S	No	EVA
rs3388942824	319	A>V	No	EVA
rs3388968695	350	K>E	No	EVA
rs3388953296	377	E>Q	No	EVA
rs3388972502	379	W>C	No	EVA
rs3388954689	412	G>S	No	EVA
rs254753368	450	A>V	No	EVA
rs3388959242	456	E>K	No	EVA
rs3388973552	521	F>I	No	EVA
rs3388974981	543	E>D	No	EVA
rs13460355	549	F>L	No	EVA
rs3388973527	552	E>D	No	EVA
rs245880632	629	A>T	No	EVA
rs3388974970	632	D>V	No	EVA
rs29989793	633	T>A	No	EVA
rs3398948296	680	E>Q	No	EVA
rs258883114	785	V>A	No	EVA

Type	Name	Position	InterPro Accession
domain	Zinc finger C2H2-type	14 - 37	IPR013087-1
domain	Zinc finger C2H2-type	62 - 85	IPR013087-2
domain	Zinc finger C2H2-type	699 - 722	IPR013087-3
domain	Zinc finger C2H2-type	728 - 750	IPR013087-4
domain	Zinc finger C2H2-type	755 - 776	IPR013087-5

		Description
EC Number
Subcellular Localization	Nucleus Chromosome Chromosome, centromere, kinetochore Cytoplasm, cytoskeleton, spindle
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
condensed chromosome	A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure.
cytoplasm	The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
Flemming body	A cell part that is the central region of the midbody characterized by a gap in alpha-tubulin staining. It is a dense structure of antiparallel microtubules from the central spindle in the middle of the intercellular bridge.
kinetochore	A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.
nuclear body	Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.
nucleoplasm	That part of the nuclear content other than the chromosomes or the nucleolus.
nucleus	A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
spindle	The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart.

Name	Definition
metal ion binding	Binding to a metal ion.

Name	Definition
attachment of mitotic spindle microtubules to kinetochore	The cell cycle process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex as part of mitotic metaphase plate congression.
protein localization to kinetochore	Any process in which a protein is transported to, or maintained at, the kinetochore.
protein localization to microtubule	A process in which a protein is transported to, or maintained at, a microtubule.
sister chromatid biorientation	The cell cycle process in which sister chromatids establish stable attachments to microtubules emanating from opposite spindle poles.

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
No homologous proteins