Q8K2W9
Gene name |
|
Protein name |
Uncharacterized protein C14orf93 homolog |
Names |
|
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:74359 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8K2W9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8K2W9-F1 | Predicted | AlphaFoldDB |
28 variants for Q8K2W9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs3389327442 | 5 | A>V | No | EVA | |
| rs3413096469 | 10 | S>F | No | EVA | |
| rs3389331290 | 83 | A>V | No | EVA | |
| rs3389251747 | 88 | E>K | No | EVA | |
| rs3389318483 | 101 | R>G | No | EVA | |
| rs3389282631 | 115 | R>Q | No | EVA | |
| rs213573443 | 134 | A>G | No | EVA | |
| rs1133875971 | 163 | G>E | No | EVA | |
| rs3389318473 | 180 | Q>* | No | EVA | |
| rs3389329946 | 180 | Q>P | No | EVA | |
| rs3405427293 | 185 | L>H | No | EVA | |
| rs259045962 | 215 | R>G | No | EVA | |
| rs3404880192 | 229 | T>FWACL* | No | EVA | |
| rs231117937 | 237 | S>A | No | EVA | |
| rs256555131 | 250 | A>T | No | EVA | |
| rs864292789 | 252 | R>H | No | EVA | |
| rs262879157 | 274 | A>T | No | EVA | |
| rs265752419 | 284 | V>I | No | EVA | |
| rs3404677822 | 319 | N>I | No | EVA | |
| rs3405117016 | 354 | H>P | No | EVA | |
| rs3389301259 | 355 | N>S | No | EVA | |
| rs3389327026 | 413 | G>E | No | EVA | |
| rs864275188 | 440 | V>A | No | EVA | |
| rs246481398 | 473 | V>I | No | EVA | |
| rs3405113367 | 484 | V>E | No | EVA | |
| rs3389345294 | 486 | A>T | No | EVA | |
| rs3389331283 | 527 | N>K | No | EVA | |
| rs3389327445 | 528 | S>W | No | EVA |
No associated diseases with Q8K2W9
No regional properties for Q8K2W9
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q8K2W9 | |||
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| extracellular region | The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| anatomical structure development | The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. |
| cell differentiation | The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. |
| positive regulation of gene expression | Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9H972 | C14orf93 | Uncharacterized protein C14orf93 | Homo sapiens (Human) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSFSATILFS | PPSGSEARCC | CCACKSETSQ | GSTGSQGGNP | PASTPITVTG | HGLAVQSSEQ |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LLHIIYQRVD | KAVGLAEAAL | GLARANNELL | KQLQEEVGEL | RQGKVCTADE | DRESRARTPP |
| 130 | 140 | 150 | 160 | 170 | 180 |
| PEEPGVLKGS | PGEASNSLPA | MEEECDSVGS | GVQVVIEELR | QLGAASTVGQ | GPLGFFAAPQ |
| 190 | 200 | 210 | 220 | 230 | 240 |
| RDARLPGCTL | AAVEGAPLLN | PMADDYVASE | GSIQRVLVPA | YAKQLSPATQ | LAIQRASSET |
| 250 | 260 | 270 | 280 | 290 | 300 |
| GPESGTKLPA | TRPEGVLGSA | ALDSALDESG | AGGAGELSRS | LGFVGSPCRI | RGTGQKNSRR |
| 310 | 320 | 330 | 340 | 350 | 360 |
| KRDLVLSKLV | HNVHNHITND | KRFNGSESIK | SSWNISVVKF | LLEKLKQELM | VSPHNYTDKE |
| 370 | 380 | 390 | 400 | 410 | 420 |
| LKGACVAYFL | TKRREYRNSL | NPFKGLKEKE | EKKLRSRRYR | LFANRSSIMR | HFGPEDQHLW |
| 430 | 440 | 450 | 460 | 470 | 480 |
| KDVTEELMSD | EEDSLNEPGV | WVARSPRFRA | QRLTELCYHL | DANSKHGTKA | NRVYGPPSDR |
| 490 | 500 | 510 | 520 | 530 | 540 |
| LPSVEAQLLP | PELYNPNFQE | DEGGGNEKGP | VSPSYDQPHK | TSCPDLNSFI | EIKVEKDEYT |
| L |