Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
0 structures for Q8JTH2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|
No variants for Q8JTH2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q8JTH2 | |||||
No associated diseases with Q8JTH2
No regional properties for Q8JTH2
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q8JTH2 | |||
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| host cell cytoplasm | The cytoplasm of a host cell. |
| host cell nucleus | A membrane-bounded organelle as it is found in the host cell in which chromosomes are housed and replicated. The host is defined as the larger of the organisms involved in a symbiotic interaction. |
| virion component | Any constituent part of a virion, a complete fully infectious extracellular virus particle. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| RNA-directed 5'-3' RNA polymerase activity | Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); uses an RNA template, i.e. the catalysis of RNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity | Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of a JAK-STAT signal cascade in a host organism by reducing the activity of host STAT1 (signal transducer and activator of transcription 1). |
| suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity | Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of a JAK-STAT signal cascade in a host organism by reducing the activity of host STAT2 (signal transducer and activator of transcription 2). |
| suppression by virus of host type I interferon-mediated signaling pathway | Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of type I interferon-mediated signaling in the host organism. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families. |
| viral transcription | The process by which a viral genome, or part of a viral genome, is transcribed within the host cell. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSKIFVNPSA | IRAGMADLEM | AEETVDLINR | NIEDNQAHLQ | GEPIEVDSLP | EDIKKLDISE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| GRSKSLVDNP | QDVECRMSED | FQMDEVEDPN | IQFQSYLDNI | GIQIVRKMRT | GERFFKIWSQ |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TVEEIISYVG | VNFPSQSGKT | TENKSTQTTP | KKVKTEPSST | PAKRSDQLSK | TEMAAKTASG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| PPALEWSTTN | DEDDVSVEAE | IAHQIAESFS | KKYKFPSRSS | GIFLYNFEQL | KMNLDDIVKE |
| 250 | 260 | 270 | 280 | 290 | |
| AKSVPGVTSL | ARDGLRLPLR | CILGWVGSSH | SKKFQLLVGS | EKLNKIMQDD | LNRYMSC |