Q8JN65

PR
Gene name
DBP
Protein name
DNA-binding protein
Names
DBP, Early 2A protein, Early E2A DNA-binding protein
Species
Snake adenovirus serotype 1 (SnAdV-1)
KEGG Pathway
vg:10973871
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-46 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

0 structures for Q8JN65

Entry ID Method Resolution Chain Position Source

No variants for Q8JN65

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8JN65

No associated diseases with Q8JN65

3 regional properties for Q8JN65

Type Name Position InterPro Accession
domain Adenovirus DNA-binding, all-alpha domain 22 - 96 IPR003176
domain Adenovirus DNA-binding, zinc-binding domain 115 - 213 IPR005376-1
domain Adenovirus DNA-binding, zinc-binding domain 225 - 313 IPR005376-2

Functions

Description
EC Number
Subcellular Localization
  • Host nucleus
  • Accumulates in infected cells
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
host cell nucleus A membrane-bounded organelle as it is found in the host cell in which chromosomes are housed and replicated. The host is defined as the larger of the organisms involved in a symbiotic interaction.
viral capsid The protein coat that surrounds the infective nucleic acid in some virus particles. It comprises numerous regularly arranged subunits, or capsomeres.

2 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
zinc ion binding Binding to a zinc ion (Zn).

4 GO annotations of biological process

Name Definition
DNA unwinding involved in DNA replication The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating unpaired template strands for DNA replication.
DNA-templated transcription The synthesis of an RNA transcript from a DNA template.
positive regulation of DNA replication Any process that activates or increases the frequency, rate or extent of DNA replication.
viral DNA strand displacement replication A viral DNA replication process where only one strand is replicated at once, and which releases a single stranded DNA (ssDNA).

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSLSKTKNPA LLAGPGDEAK EKVQAALELL HKFGSAFKVD TAGFSFHPES PECDKIFGAY
70 80 90 100 110 120
LKNVKHVPTY SSAKTLTSVG GRILYAATCQ YVKLTPVTNL TGCTLWEHGW GQNLKCYHGE
130 140 150 160 170 180
GMCRKKNEIE MAATSESGVA ALKEGRGAVE INRWGRQVVK ITQENYVICM EDLQSRFNQP
190 200 210 220 230 240
SANSCGLSFS DSDKARSAME NATELTRSIF SQAKMDHLLF MPICCYCNYG GKMILGRQLC
250 260 270 280 290 300
KLTPFSISGT EGLREEDVSP VQAVSVRHPA VFVFQCCNAT GGSKGKTSCD FKISHADLLQ
310 320 330 340 350 360
VLNLVRKMWL EVMGYPMPIH FPRFKWSPSL RVKNALLPEG SVNEDENPFG LDNSEDEEEV
370 380 390
VPPSPPSPAR KRTRTTVAEV HHKKKKKIVL ESSEEDE