Q8HYJ3

PR
Gene name
FUT5
Protein name
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5
Names
3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT5, Fucosyltransferase 5, Fucosyltransferase V, Fuc-TV, FucT-V, Galactoside 3-L-fucosyltransferase
Species
Hylobates lar (Common gibbon) (White-handed gibbon)
KEGG Pathway
EC number
2.4.1.65: Hexosyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

18-92 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8HYJ3

Entry ID Method Resolution Chain Position Source
AF-Q8HYJ3-F1 Predicted AlphaFoldDB

No variants for Q8HYJ3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8HYJ3

No associated diseases with Q8HYJ3

1 regional properties for Q8HYJ3

Type Name Position InterPro Accession
domain Fucosyltransferase, N-terminal 75 - 183 IPR031481

Functions

Description
EC Number 2.4.1.65 Hexosyltransferases
Subcellular Localization
  • Golgi apparatus, Golgi stack membrane ; Single-pass type II membrane protein
  • Membrane-bound form in trans cisternae of Golgi
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
Golgi cisterna membrane The lipid bilayer surrounding any of the thin, flattened compartments that form the central portion of the Golgi complex.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

2 GO annotations of molecular function

Name Definition
3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity Catalysis of the reaction: GDP-L-fucose + beta-D-galactosyl-(1,3)-N-acetyl-D-glucosaminyl-R = GDP + beta-D-galactosyl-(1,3)-[alpha-L-fucosyl-(1,4)]-N-acetyl-D-glucosaminyl-R.
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity Catalysis of the reaction: GDP-beta-L-fucose + beta-D-galactosyl-(1,4)-N-acetyl-D-glucosaminyl-R = GDP + 1,4-beta-D-galactosyl-(1,4)-[alpha-L-fucosyl-(1,3)]-N-acetyl-D-glucosaminyl-R.

4 GO annotations of biological process

Name Definition
ceramide metabolic process The chemical reactions and pathways involving ceramides, any N-acylated sphingoid.
oligosaccharide metabolic process The chemical reactions and pathways involving oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.
protein N-linked glycosylation A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the N4 atom of peptidyl-asparagine, the omega-N of arginine, or the N1' atom peptidyl-tryptophan.
protein O-linked glycosylation A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the hydroxyl group of peptidyl-serine, peptidyl-threonine, peptidyl-hydroxylysine, or peptidyl-hydroxyproline, or via the phenol group of peptidyl-tyrosine, forming an O-glycan.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDLLGAAKPQ WPWRRCLAGL LFQLLVAVCF FSYLRVSRDD ATGSPRPRLM AVEPVTGAPN
70 80 90 100 110 120
GSRCQDSMAA PARPTLLILL WTWPFNTPVA LPRCSEMVPG AADCNITADS NVYPQADAVI
130 140 150 160 170 180
VHHWDIMRTP SANLPPPTRP QGQRWIWFSM ESPSNCRHLE ALDGYFNLTM SYRSDSDIFT
190 200 210 220 230 240
PYGWLEPWSG QPAHPPLNLS AKTELVAWAV SNWEPGSARV RYYQSLQAHL KVDVYGRSHK
250 260 270 280 290 300
PLPQGTMMET LSRYKFYLAF ENSLHPDYIT EKLWRNALEA WAVPVVLAPS RSNYERFLPP
310 320 330 340 350 360
DAFIHVDDFQ SPKDLARYLQ ELDKDHARYL SYFRWRETLR PRSFSWALDF CKACWKLQQE
370
SRYQTVRSIA AWFN