Q8HY56

PR
Gene name
GGTA1
Protein name
N-acetyllactosaminide alpha-1,3-galactosyltransferase
Names
UDP-galactose:beta-D-galactosyl-1,4-N-acetyl-D-glucosaminide alpha-1,3-galactosyltransferase, Galactosyltransferase
Species
Felis catus (Cat) (Felis silvestris catus)
KEGG Pathway
fca:493877
EC number
2.4.1.87: Hexosyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

38-114 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8HY56

Entry ID Method Resolution Chain Position Source
AF-Q8HY56-F1 Predicted AlphaFoldDB

No variants for Q8HY56

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8HY56

No associated diseases with Q8HY56

No regional properties for Q8HY56

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q8HY56

Functions

Description
EC Number 2.4.1.87 Hexosyltransferases
Subcellular Localization
  • Golgi apparatus, Golgi stack membrane ; Single-pass type II membrane protein
  • Membrane-bound form in trans cisternae of Golgi
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

5 GO annotations of cellular component

Name Definition
Golgi apparatus A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.
Golgi cisterna Any of the thin, flattened membrane-bounded compartments that form the central portion of the Golgi complex.
Golgi cisterna membrane The lipid bilayer surrounding any of the thin, flattened compartments that form the central portion of the Golgi complex.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
vesicle Any small, fluid-filled, spherical organelle enclosed by membrane.

2 GO annotations of molecular function

Name Definition
metal ion binding Binding to a metal ion.
N-acetyllactosaminide 3-alpha-galactosyltransferase activity Catalysis of the reaction: beta-D-galactosyl-(1,4)-beta-N-acetyl-D-glucosaminyl-R + UDP-galactose = alpha-D-galactosyl-(1,3)-beta-D-galactosyl-(1,4)-beta-N-acetyl-D-glucosaminyl-R + UDP.

3 GO annotations of biological process

Name Definition
carbohydrate metabolic process The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
lipid glycosylation Covalent attachment of a glycosyl residue to a lipid molecule.
protein glycosylation A protein modification process that results in the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P23336 Ggta1 N-acetyllactosaminide alpha-1,3-galactosyltransferase Mus musculus (Mouse) PR
10 20 30 40 50 60
MNVKGRVVLS MLVVSTVIVV FWEYINSPEG SFLWIYHSKN PEVGDSSTQK GWWFPSWFNN
70 80 90 100 110 120
RTHSYPEEEA VDEGDEQRKE NSEELQLSDW FNPQKRPDVV TVTEWKAPVV WEGTYNKAIL
130 140 150 160 170 180
ENYYARQKIT VGLTVFAVGR YIEHYLEEFL ISANRYFMVG HKVIFYIMVD DVSKMPLIEL
190 200 210 220 230 240
GPLRSFKVFE IKPEKRWQDI SMMRMKIIGE HIVAHIQHEV DFLFCMDVDQ VFQDSFGVET
250 260 270 280 290 300
LGQSVAQLQA WWYKADPDEF TYERRKESAA YIPFGEGDFY YHAAIFGGTP TQVLNITQEC
310 320 330 340 350 360
FKGILQDKKN DIEAEWHDES HLNKYFLLNK PTKILSPEYC WDYHIGLPSD IKIVKISWQT
KEYNLVRNNI