Q8HXX2

PR
Gene name
MPI (QccE-15018)
Protein name
Mannose-6-phosphate isomerase
Names
Phosphohexomutase, Phosphomannose isomerase, PMI
Species
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
KEGG Pathway
EC number
5.3.1.8: Interconverting aldoses and ketoses
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

81-227 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8HXX2

Entry ID Method Resolution Chain Position Source
AF-Q8HXX2-F1 Predicted AlphaFoldDB

No variants for Q8HXX2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8HXX2

No associated diseases with Q8HXX2

No regional properties for Q8HXX2

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q8HXX2

Functions

Description
EC Number 5.3.1.8 Interconverting aldoses and ketoses
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
mannose-6-phosphate isomerase activity Catalysis of the reaction: D-mannose 6-phosphate = D-fructose 6-phosphate.
zinc ion binding Binding to a zinc ion (Zn).

2 GO annotations of biological process

Name Definition
carbohydrate metabolic process The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
GDP-mannose biosynthetic process The chemical reactions and pathways resulting in the formation of GDP-mannose, a substance composed of mannose in glycosidic linkage with guanosine diphosphate.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAAPRVFPLS CAVQQYAWGK MGYNSEVARL LASSDPLAQI AEDKPYAELW MGTHPRGDAK
70 80 90 100 110 120
IFDNGISQKT LGQWIAENQD SLGSKVKDTF NGNLPFLFKV LSVETPLSIQ AHPNKELAEK
130 140 150 160 170 180
LHLQAPQHYP DANHKPEMAI ALTPFQGLCG FRPVEEIVTF LKKVPEFQFL IGDEAATHLK
190 200 210 220 230 240
QTMSHDSQAV ASALQSCFSH LMKSEKKVVA EQLNLLVKRI SQQVAAGNNM EDIFGELLLQ
250 260 270 280 290 300
LHQQYPGDIG CFAIYFLNLL NLKPGEAMFL EANVPHAYLK GDCVECMACS DNTVRAGLTP
310 320 330 340 350 360
KFIDVPTLCE MLSYTPSSSK DRLFLPTRSQ EDPYLSIYDP PVPDFAIMKM EVPGSVTEYK
370 380 390 400 410 420
VLALDSASIL LVVQGTVIAS TPTTQTPIPL QRGGVLFIGA NESVSLKLTE PKDLLIFRAC
CLL