Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q8H1G3

Entry ID Method Resolution Chain Position Source
AF-Q8H1G3-F1 Predicted AlphaFoldDB

12 variants for Q8H1G3

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_1_19136639_T_A 5 H>Q No 1000Genomes
tmp_1_19136637_C_T 5 H>Y No 1000Genomes
tmp_1_19136648_G_T 8 L>F No 1000Genomes
ENSVATH04934762 18 G>V No 1000Genomes
ENSVATH04934764 32 A>T No 1000Genomes
ENSVATH13506818 46 H>R No 1000Genomes
tmp_1_19136824_G_A 67 C>Y No 1000Genomes
ENSVATH04934766 78 V>F No 1000Genomes
ENSVATH14288379 80 L>F No 1000Genomes
tmp_1_19136865_G_T 81 D>Y No 1000Genomes
ENSVATH13506836 212 T>I No 1000Genomes
tmp_1_19139357_G_A 396 R>H No 1000Genomes

No associated diseases with Q8H1G3

No regional properties for Q8H1G3

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q8H1G3

Functions

Description
EC Number
Subcellular Localization
  • Vacuole membrane ; Multi-pass membrane protein
  • Tonoplast
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
vacuolar membrane The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell.

1 GO annotations of molecular function

Name Definition
cation transmembrane transporter activity Enables the transfer of cation from one side of a membrane to the other.

1 GO annotations of biological process

Name Definition
zinc ion transport The directed movement of zinc (Zn II) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q6PML9 SLC30A9 Zinc transporter 9 Homo sapiens (Human) PR
10 20 30 40 50 60
MQSSHRILSR LLHSPRKGYI RASVGGSVHF LALFDEKDNG FVDTTHRSFS SLIRSSSHVR
70 80 90 100 110 120
GLISTNCLNK GLGVRCSVSL DRETPLIDTY SSHRNFFTRA KQVKRIEIND QHSQRAVTTA
130 140 150 160 170 180
LWCNFLVFSL KFGVWWTSSS HVIMAEVVHS VADFANQALL AYGLSSSRRA PDALHPYGYS
190 200 210 220 230 240
KERFVWSLIS AVGIFCLGSG ATIVNGVQNL WTSSPPPNME LAAVVIGGSF LIEGASLLVA
250 260 270 280 290 300
IQSVKKGAAQ EGMTIRDYIW RGHDPTSVAV MTEDGAAVAG LAIAAASLVA VRMTGNPIYD
310 320 330 340 350 360
PIGSIVVGNL LGMVAIFLIQ RNRHALIGRA MDDQDMSKVL KFLRNDSVVD SLYDCKSEVI
370 380 390 400 410 420
GPGSFRFKAE IDFNGQMVVQ NYLKRTGREE WAKMFREAAK NGDDSAMLNI MSNYGEEVVT
430 440 450
ALGSEVDRLE KEIQELVPGI QHVDIEAHNP TPTDPSL