Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

2 structures for Q8GYN5

Entry ID Method Resolution Chain Position Source
2NUD X-ray 230 A C/D 142-176 PDB
AF-Q8GYN5-F1 Predicted AlphaFoldDB

34 variants for Q8GYN5

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_3_9132462_C_T 2 A>V No 1000Genomes
tmp_3_9133033_G_A 35 S>N No 1000Genomes
ENSVATH00347875 36 K>R No 1000Genomes
ENSVATH00347876 38 M>V No 1000Genomes
ENSVATH00347877 45 Y>S No 1000Genomes
ENSVATH05909966 50 Q>L No 1000Genomes
ENSVATH05909968 52 Q>H No 1000Genomes
ENSVATH02199324 56 H>P No 1000Genomes
ENSVATH02199324 56 H>R No 1000Genomes
ENSVATH05909969 61 R>K No 1000Genomes
ENSVATH05909970 67 V>L No 1000Genomes
ENSVATH00347878 68 D>V No 1000Genomes
ENSVATH05909971 80 R>G No 1000Genomes
tmp_3_9133168_G_A 80 R>Q No 1000Genomes
ENSVATH05909972 86 K>T No 1000Genomes
ENSVATH00347880 88 F>L No 1000Genomes
ENSVATH00347881 88 F>Y No 1000Genomes
ENSVATH00347882 89 G>D No 1000Genomes
ENSVATH10965270 91 A>V No 1000Genomes
ENSVATH10965271 96 N>T No 1000Genomes
tmp_3_9133245_G_C 106 A>P No 1000Genomes
tmp_3_9133279_C_T 117 P>L No 1000Genomes
ENSVATH05909973 118 L>F No 1000Genomes
ENSVATH00347883 129 S>T No 1000Genomes
ENSVATH00347884 134 T>A No 1000Genomes
ENSVATH10965272 136 L>F No 1000Genomes
ENSVATH10965330 144 K>R No 1000Genomes
ENSVATH00347889 147 V>A No 1000Genomes
tmp_3_9133545_G_A 180 A>T No 1000Genomes
ENSVATH05909976 181 N>K No 1000Genomes
ENSVATH05909977 192 Q>L No 1000Genomes
ENSVATH05909978 194 S>T No 1000Genomes
tmp_3_9133604_C_G 199 N>K No 1000Genomes
tmp_3_9133730_G_A 207 G>S No 1000Genomes

No associated diseases with Q8GYN5

6 regional properties for Q8GYN5

Type Name Position InterPro Accession
conserved_site ATP-dependent RNA helicase DEAD-box, conserved site 270 - 278 IPR000629
domain Helicase, C-terminal 336 - 498 IPR001650
domain DEAD/DEAH box helicase domain 135 - 313 IPR011545
domain Helicase superfamily 1/2, ATP-binding domain 130 - 340 IPR014001
domain RNA helicase, DEAD-box type, Q motif 111 - 139 IPR014014
domain DDX52/Rok1, DEAD-box helicase domain 122 - 328 IPR044764

Functions

Description
EC Number
Subcellular Localization
  • Endomembrane system ; Peripheral membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

5 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
endomembrane system A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.
extrinsic component of plasma membrane The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

5 GO annotations of biological process

Name Definition
defense response to bacterium Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.
negative regulation of plant-type hypersensitive response Any process that stops, prevents, or reduces the frequency, rate or extent of the hypersensitive response in a plant.
plant-type hypersensitive response The rapid, localized death of plant cells in response to invasion by a pathogen.
protein phosphorylation The process of introducing a phosphate group on to a protein.
response to molecule of bacterial origin Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of bacterial origin such as peptides derived from bacterial flagellin.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MARSNVPKFG NWEAEENVPY TAYFDKARKT RAPGSKIMNP NDPEYNSDSQ SQAPPHPPSS
70 80 90 100 110 120
RTKPEQVDTV RRSREHMRSR EESELKQFGD AGGSSNEAAN KRQGRASQNN SYDNKSPLHK
130 140 150 160 170 180
NSYDGTGKSR PKPTNLRADE SPEKVTVVPK FGDWDENNPS SADGYTHIFN KVREERSSGA
190 200 210
NVSGSSRTPT HQSSRNPNNT SSCCCFGFGG K