Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q8GYH6

Entry ID Method Resolution Chain Position Source
AF-Q8GYH6-F1 Predicted AlphaFoldDB

17 variants for Q8GYH6

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_3_3417490_C_A 3 S>I No 1000Genomes
ENSVATH05806673 13 G>E No 1000Genomes
tmp_3_3417448_C_A 17 G>V No 1000Genomes
tmp_3_3417403_A_G 32 V>A No 1000Genomes
tmp_3_3417028_A_C 44 L>V No 1000Genomes
ENSVATH10594834 72 L>S No 1000Genomes
ENSVATH00316159 84 I>M No 1000Genomes
ENSVATH05806657 91 V>G No 1000Genomes
ENSVATH05806658 91 V>L No 1000Genomes
tmp_3_3416877_C_T 94 R>Q No 1000Genomes
ENSVATH05806653 104 H>N No 1000Genomes
tmp_3_3416748_G_A 105 S>L No 1000Genomes
tmp_3_3416697_G_A 122 S>F No 1000Genomes
tmp_3_3416487_C_T 158 A>T No 1000Genomes
tmp_3_3416209_G_C 191 D>E No 1000Genomes
ENSVATH10594828 192 K>N No 1000Genomes
ENSVATH05806638 203 H>Y No 1000Genomes

No associated diseases with Q8GYH6

1 regional properties for Q8GYH6

Type Name Position InterPro Accession
domain Reticulon 41 - 224 IPR003388

Functions

Description
EC Number
Subcellular Localization
  • Endoplasmic reticulum membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
endoplasmic reticulum membrane The lipid bilayer surrounding the endoplasmic reticulum.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
response to bacterium Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDSLSDIDGD FDGRNEGGSS SDYRLLGRQI TVHQFMGGGK AADLLLWRRR HLSLGVIIIS
70 80 90 100 110 120
TVAWLIFEFS GLPFLSVSSD VLLIVIMISF VHARVSAFRN RQLHSLPELV LSEEMVNSAA
130 140 150 160 170 180
ASFRIKLNHL LVMAHDVTVG NDFRLFFKVV ICLWLLSAIG SYISLCTLLY IGTILSVTIP
190 200 210 220
ALYSKYQSKV DKCCGTIHRR LSHHYKIVDE NVISRLSWSL SKDKDS