Q8GEA9

PR
Gene name
bgaA
Protein name
Beta-galactosidase BgaA
Names
Beta-gal
Species
Thermus sp
KEGG Pathway
EC number
3.2.1.23: Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

333-420 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8GEA9

Entry ID Method Resolution Chain Position Source
AF-Q8GEA9-F1 Predicted AlphaFoldDB

No variants for Q8GEA9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8GEA9

No associated diseases with Q8GEA9

3 regional properties for Q8GEA9

Type Name Position InterPro Accession
domain Glycoside hydrolase, family 42, N-terminal 5 - 389 IPR013529
domain Beta-galactosidase trimerisation 398 - 589 IPR013738
domain Beta-galactosidase C-terminal 597 - 644 IPR013739

Functions

Description
EC Number 3.2.1.23 Glycosidases, ie enzymes hydrolyzing O- and S-glycosyl compounds
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
beta-galactosidase complex A protein complex that possesses beta-galactosidase activity, i.e. catalyzes the hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides. In E. coli, the complex is a homotetramer; dimeric and hexameric beta-galactosidase complexes have been observed in other species.

2 GO annotations of molecular function

Name Definition
beta-galactosidase activity Catalysis of the hydrolysis of terminal, non-reducing beta-D-galactose residues in beta-D-galactosides.
metal ion binding Binding to a metal ion.

1 GO annotations of biological process

Name Definition
galactose metabolic process The chemical reactions and pathways involving galactose, the aldohexose galacto-hexose. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLGVCYYPEH WPKARWKEDA RRMREAGLSY VRVGEFAWAL LEPEPGRLEW GWLDEALATL
70 80 90 100 110 120
AAEGLKVVLG TPTATPPKWL VDRYPEVLPV DREGRRRRFG GRRHYCFSSP AYREEARRIV
130 140 150 160 170 180
TLLAERYGGL EAVAGFQTDN EYGCHGTVRC YCPRCQEAFR GWLKARYGTI EALNEAWGTA
190 200 210 220 230 240
FWSQRYRNFT EVELPHLTVA EPNPSHLLDY YRFASDQVRA FNRLQVEILR AHAPGKFITH
250 260 270 280 290 300
NFMGFFTDLD AFALAQDLDF ASWDSYPLGF TDLMPLPPEE KLRYARTGHP DVAAFHHDLY
310 320 330 340 350 360
RGVGRGRFWV MEQQPGPVNW APHNPSPTPG MVRLWTWEAL AHGAEVVSYF RWRQAPFAQE
370 380 390 400 410 420
QMHAGLHRPD SAPDQGFFEA KQVAEELAAL ALPPVAQAPV ALVFDYEAAW VYEVQPQGAE
430 440 450 460 470 480
WSYLGLIYLF YSALRRLGLD VDVVPPGASL RGYALTVVPS LPIVRGEALK AFQEAEGIVL
490 500 510 520 530 540
FGPRSGSKTE TFQIPRELPP GPLQALLPLK VVRVESLPPG LLEVAEGPMG RFSLGLWREW
550 560 570 580 590 600
VESPLRPWLA FADGGGALYR EGRYLYLAAW PSPELLGVLL AGLAQEAGLR PVFLPEGLRL
610 620 630 640
RRRGPWVFAF NYGPEAVEAP APEGARFLLG GKRVGPYDLA VWEEA