Q8FM94

PR
Gene name
clpB (CE2613)
Protein name
Chaperone protein ClpB
Names
Species
Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)
KEGG Pathway
cef:CE2613
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

112-188 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8FM94

Entry ID Method Resolution Chain Position Source
AF-Q8FM94-F1 Predicted AlphaFoldDB

No variants for Q8FM94

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8FM94

No associated diseases with Q8FM94

9 regional properties for Q8FM94

Type Name Position InterPro Accession
domain AAA+ ATPase domain 199 - 344 IPR003593-1
domain AAA+ ATPase domain 600 - 758 IPR003593-2
domain ATPase, AAA-type, core 204 - 308 IPR003959-1
domain ATPase, AAA-type, core 599 - 751 IPR003959-2
domain Clp, repeat (R) domain 1 - 147 IPR004176
conserved_site ClpA/B, conserved site 1 296 - 308 IPR018368
domain Clp ATPase, C-terminal 757 - 846 IPR019489
conserved_site ClpA/B, conserved site 2 634 - 652 IPR028299
domain ClpA/ClpB, AAA lid domain 344 - 446 IPR041546

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.

2 GO annotations of biological process

Name Definition
protein refolding The process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.
response to heat Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSSFNPTTKT SEAMQAALQQ ASANGNPDIR PAHLLVAILD QADGVAAPVL TAAGVDPKTI
70 80 90 100 110 120
LAEAQKLVDG YPKASGSNLA NPNFNRDALN ALTASQELAG ELGDEYVSTE VLLAGIARGK
130 140 150 160 170 180
SDAADLLKGK GATYDAIKAA FQSVRGSQKV TSQDPEGQFQ ALEKYSTDLT KLAREGKIDP
190 200 210 220 230 240
VIGRDQEIRR VVQVLSRRTK NNPVLIGEPG VGKTAIVEGL ARRIVAGDVP ESLKGKTLIS
250 260 270 280 290 300
LDLGSMVAGA KYRGEFEERL KAVLDEIKGA NGEIVTFIDE LHTIVGAGAS GESAMDAGNM
310 320 330 340 350 360
IKPLLARGEL RLVGATTLNE YRKYIEKDTA LERRFQQVYV GEPSVEDTVG ILRGLKERYE
370 380 390 400 410 420
VHHGVRIQDS ALVAAAELSH RYITSRFLPD KAIDLVDEAA SRLRMEIDSS PQEIDELERI
430 440 450 460 470 480
VRRLEIEEVA LTKETDVASR ERLERLRSEL ADEREKLSEL KARWQNEKAV IDDVRKFKEE
490 500 510 520 530 540
LEALRSESDI AEREGDYGRV AELRYGRIPE LEKKIAEAEE KIGGADNSML TEEVTPEVIA
550 560 570 580 590 600
EVVSAWTGIP AGKMMQGETE KLLNMERFLG KRVVGQHEAV TAVSDAVRRS RAGVADPNRP
610 620 630 640 650 660
TGSFLFLGPT GVGKTELAKA VSEFLFDDER AMVRIDMSEY SEKHSVARLV GAPPGYVGYD
670 680 690 700 710 720
QGGQLTEAVR RRPYTTVLFD EVEKAHPDVF DILLQVLDDG RLTDGQGRTV DFRNTILILT
730 740 750 760 770 780
SNLGAGGTRE QMMDAVKMAF KPEFINRLDD IVVFDPLSQE QLASIVEIQI SQLAERLSDR
790 800 810 820 830 840
RLTLRVSDAA KLWLAERGYD PAYGARPLRR LIQQAIGDQL AKELLAGEIR DGDRVLVDVA
850
DGGQYLAVSR EH