Q8FJE7
Gene name |
rlmC |
Protein name |
23S rRNA (uracil(747)-C(5))-methyltransferase RlmC |
Names |
23S rRNA(m5U747)-methyltransferase |
Species |
Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) |
KEGG Pathway |
ecc:c0992 |
EC number |
2.1.1.189: Methyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8FJE7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8FJE7-F1 | Predicted | AlphaFoldDB |
No variants for Q8FJE7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q8FJE7 | |||||
No associated diseases with Q8FJE7
6 regional properties for Q8FJE7
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Zinc finger, Sec23/Sec24-type | 58 - 98 | IPR006895 |
| domain | Sec23/Sec24, trunk domain | 127 - 392 | IPR006896 |
| domain | Sec23/Sec24, helical domain | 520 - 617 | IPR006900 |
| domain | Gelsolin-like domain | 633 - 719 | IPR007123 |
| domain | Sec23/Sec24 beta-sandwich | 403 - 506 | IPR012990 |
| domain | Sec23, C-terminal | 611 - 731 | IPR037550 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.1.1.189 | Methyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| 4 iron, 4 sulfur cluster binding | Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands. |
| iron ion binding | Binding to an iron (Fe) ion. |
| rRNA (uridine-C5-)-methyltransferase activity | Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing C5-methyluridine. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MQCALYDAGR | CRSCQWITQP | IPEQLSAKTA | DLKNLLADFP | VEEWCAPVSG | PEQGFRNKAK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| MVVSGSVEKP | LLGMLHRDGT | PEDLCDCPLY | PASFAPVFAA | LKPFIARAGL | TPYNVARKRG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ELKYILLTES | QSDGGMMLRF | VLRSDTKLAQ | LRKALPWLQE | QLPQLKVITV | NIQPVHMAIM |
| 190 | 200 | 210 | 220 | 230 | 240 |
| EGETEIYLTE | QQALAERFND | VPLWIRPQSF | FQTNPAVASQ | LYATARDWVR | QLPVKHMWDL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| FCGVGGFGLH | CATPDMQLTG | IEIAPEAIAC | AKQSAAELGL | TRLQFQALDS | TQFATAQGEV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| PELVLVNPPR | RGIGKPLCDY | LSTMAPRFII | YSSCNAQTMA | KDIRELPGYR | IERVQLFDMF |
| 370 | |||||
| PHTAHYEVLT | LLVQQ |