Q8F7K1

PR
Gene name
infB
Protein name
Translation initiation factor IF-2
Names
Species
Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)
KEGG Pathway
lil:LA_0943
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-288 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8F7K1

Entry ID Method Resolution Chain Position Source
AF-Q8F7K1-F1 Predicted AlphaFoldDB

No variants for Q8F7K1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8F7K1

No associated diseases with Q8F7K1

6 regional properties for Q8F7K1

Type Name Position InterPro Accession
domain ABC transporter-like, ATP-binding domain 6 - 244 IPR003439
domain AAA+ ATPase domain 34 - 221 IPR003593
domain ABC3 transporter permease protein domain 530 - 644 IPR003838
conserved_site ABC transporter-like, conserved site 146 - 160 IPR017871
domain MacB, ATP-binding domain 6 - 222 IPR017911
domain MacB-like periplasmic core domain 275 - 494 IPR025857

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

1 GO annotations of biological process

Name Definition
translational initiation The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEDKNKTIKE TLQGSADAGK RKKLIIKKKG DDPSTPSPAA SPKKETVAES APSSKPPVMP
70 80 90 100 110 120
LPLPGDSGQS PIVRPAPSSH SPAKREESPG KQDAGRPPRD KDTRQGGGSS YPPSRSPFQK
130 140 150 160 170 180
EDSNIIVSRP IQRTGPSRPN SGGGYQGNRG PGQGGGGYQG NRGPGQGGGG YQGNRGPGPG
190 200 210 220 230 240
QGGGGYQGNR GPGQGGGGYQ GNRGPRSGGT GTRPMPITSA EVELSQSRGS SVTSKKKGHD
250 260 270 280 290 300
KEKSTSDRDF SGAENTKFFK QKFKKTKVVG VSGVSVPKEI TLLENVQVGE LAKKMNLKPG
310 320 330 340 350 360
DVIGKLMKMG MMVTINNIID AETAALLADE YGCKVKVVSL YEETIIEEEK DNQEDYINRP
370 380 390 400 410 420
PVVTIMGHVD HGKTKLLDTI RRSSVIDTES GGITQHIGAY QVRTARGLIT FLDTPGHEAF
430 440 450 460 470 480
TSMRARGAKV TDIVVLVVAA DDGVMPQTLE AISHAKAAEV PILVAINKID LPAANPEKIM
490 500 510 520 530 540
QELANHGLQS EEWGGETMYA KISARENIGI DKLLEMILLQ AEVMDLKANP KRRAKGTIIE
550 560 570 580 590 600
AKLDPGRGSV ATVLIQNGTL RVGDPFVAGV FSGRVRAMYN DLGQLIQEAG PAFPAQVTGI
610 620 630 640 650 660
DGVPDAGAPF DAMADEKEAR NISQHRIEFE RIGNAGAATG TSSKVTLENM NEFIKQGALK
670 680 690 700 710 720
ELKVIIKADV RGSAEAIKES LEKLSTPEVK LNVIQSGAGA IVDMDVMLAS ASNALIIGFH
730 740 750 760 770 780
VRANPKTIAL AEKEGVQIKY YNIIYQVVDE IKLAMEGLLE PEKIEEVIGT AEIREIFKVS
790 800 810 820 830 840
KIGNIAGCMV LSGKIQKSAN IRVIGDGVTK FEGKLKSLKR VKDDVNDVVA GFECGIQVDG
850 860
YNDFKVGDTI EAYNVTVIKR KLE