Q8F394

PR
Gene name
panC
Protein name
Pantothenate synthetase
Names
PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme
Species
Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)
KEGG Pathway
lil:LA_2514
EC number
6.3.2.1: Acid--amino-acid ligases (peptide synthases)
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

152-229 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8F394

Entry ID Method Resolution Chain Position Source
AF-Q8F394-F1 Predicted AlphaFoldDB

No variants for Q8F394

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8F394

No associated diseases with Q8F394

1 regional properties for Q8F394

Type Name Position InterPro Accession
domain Cytidyltransferase-like domain 26 - 72 IPR004821

Functions

Description
EC Number 6.3.2.1 Acid--amino-acid ligases (peptide synthases)
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
pantoate-beta-alanine ligase activity Catalysis of the reaction: ATP + (R)-pantoate + beta-alanine = AMP + diphosphate + (R)-pantothenate.

1 GO annotations of biological process

Name Definition
pantothenate biosynthetic process The chemical reactions and pathways resulting in the formation of pantothenate, the anion of pantothenic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MIVCKTPEEV LDQVRLWKAQ GKRIGFVPTM GYLHEGHASL FEECISKADK TVVSIFVNPA
70 80 90 100 110 120
QFNDPEDYAK YPVNTEGDLK LCESKKVDLV FLPNKETIYP DGIPDIVLKI PNLMKSLCAV
130 140 150 160 170 180
SRPGHFEGVL LVIFRLFHFV QPDFAFFGKK DYQQYLLIRE FCNTLAFPIE VIGCETVRSS
190 200 210 220 230 240
QGLALSSRNS RLSETEKEES LLIYRSLKLG ENQIFSGIKN PLLVKEIMKD VLDSSSKIRL
250 260 270 280
DYLEILNADT LDPLEVLEGE ILLAIAAFIG PVRLIDNLTL SVPTS