Q8EWU0

PR
Gene name
infB
Protein name
Translation initiation factor IF-2
Names
Species
Malacoplasma penetrans (strain HF-2) (Mycoplasma penetrans)
KEGG Pathway
mpe:MYPE1110
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-65 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8EWU0

Entry ID Method Resolution Chain Position Source
AF-Q8EWU0-F1 Predicted AlphaFoldDB

No variants for Q8EWU0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8EWU0

No associated diseases with Q8EWU0

6 regional properties for Q8EWU0

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 454 - 623 IPR000795
domain Small GTP-binding protein domain 457 - 613 IPR005225
domain Translation initiation factor IF-2, N-terminal 1 - 50 IPR006847-1
domain Translation initiation factor IF-2, N-terminal 374 - 425 IPR006847-2
domain Translation initiation factor IF- 2, domain 3 729 - 844 IPR023115
domain Translation initiation factor IF-2, domain II 629 - 724 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEVFMAKNVK TKSKNKNKKI VDNRTNIDIK SQFKKVETGI KNGVFVFTNN LTIDEFSKKI
70 80 90 100 110 120
NKHSAEIIKY LFLKGINCNL NTLLDERQMG ELCLEFGYDF KKEIQINEDN FLDNIKFEDR
130 140 150 160 170 180
EDLLDKRPPI VTIMGHVDHG KTTLLDTIRK SKVAATEAGN ITQSIGAYQV EWKKHLITFF
190 200 210 220 230 240
DTPGHEAFSK MRAVGADLTD IVVLVVAADD GLKPQTEEAI DHALFAKAPI IVFINKMDKK
250 260 270 280 290 300
DANIEKIYSQ LAEKNVLCEE WGGKTMVIKG SALNNQGIDE LLEAIIVTAE IMELKANPKR
310 320 330 340 350 360
LANGITIEAS MDKGEGAVAD LLVQSGTLAV NDYILVGEYY GKVKKMVDFN RKEIKTALPS
370 380 390 400 410 420
TPVRISGLNG IPKSGDKWIV TNDEKLLKEL SEKRQLNTKQ RKLSNFGTNL NENSQGIKEL
430 440 450 460 470 480
NVILKTDNNG SLEAIKGLLS SIEVTGAKLN LVRAAIGSIN ESDIDLARTS KSLVVIFNTK
490 500 510 520 530 540
VSSKVSDYAI SMGITIKNYN IIYQIKDEIE RLLKGILDPV FVEKEIGSVE IRQLWSHSSI
550 560 570 580 590 600
GVIAGGRVLT GEIKRNAFAR IKRKDKEIIS NAKINSLRHG KDSIASAAAG KECGFTLENF
610
NDFVEGDIVE IYEIVGETHE