Q8EVL6

PR
Gene name
secA
Protein name
Protein translocase subunit SecA
Names
Species
Malacoplasma penetrans (strain HF-2) (Mycoplasma penetrans)
KEGG Pathway
mpe:MYPE5470
EC number
7.4.2.8: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

759-859 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8EVL6

Entry ID Method Resolution Chain Position Source
AF-Q8EVL6-F1 Predicted AlphaFoldDB

No variants for Q8EVL6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8EVL6

No associated diseases with Q8EVL6

7 regional properties for Q8EVL6

Type Name Position InterPro Accession
domain Helicase, C-terminal 420 - 595 IPR001650
domain SecA DEAD-like, N-terminal 8 - 384 IPR011115
domain SecA Wing/Scaffold 570 - 775 IPR011116
domain SecA, preprotein cross-linking domain 229 - 340 IPR011130
domain Helicase superfamily 1/2, ATP-binding domain 90 - 233 IPR014001
domain SecA motor DEAD 3 - 572 IPR014018
domain SecA, C-terminal helicase domain 402 - 542 IPR044722

Functions

Description
EC Number 7.4.2.8 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Cytoplasm
  • Distribution is 50-50
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
protein-exporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins.

3 GO annotations of biological process

Name Definition
intracellular protein transmembrane transport The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
protein import The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event.
protein targeting The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MHMKIKKFKK IKKKSKILVK AKLIAQQVEN NREEYSALSI EDLRIRTDYL VDGLAKDKFT
70 80 90 100 110 120
LEDIIVDALS IAREIIYREH GMLAYEVQMM GAYVVHTGDF AEMYTGEGKS LTLLLVSFVN
130 140 150 160 170 180
ALTKRGVHIV TVNEYLVERD ALFAQKAFEK LGITVGYNTS KLSKATKKEM FARDITYTTN
190 200 210 220 230 240
SELGFDYLKD NMVRDINEKV IRELFFVIVD EADSVLIDEA RTPLIISGQP KEDFSLYLDI
250 260 270 280 290 300
DKFVGSLAED DYKIDNESNT IALTDQGVSK AEKFFNLTNL YSVESAEIVH KITNSLVAHY
310 320 330 340 350 360
IFANGKEYLV KDDKIYLVDQ FTGRVLEGRS YNAGLQQAIQ AKERVTIEPE NVVMATITYQ
370 380 390 400 410 420
SFFRLYEKLS GVSGTAMTEA EEFLKIYNMV VVRIPTNKPV ARIDKQDYIF GTKRVKWNHV
430 440 450 460 470 480
IQEIVNRHET GQPILVGTAS VTDSEIIHER LTELKIPHEV LNARDNTKEA EIVKHAGEKG
490 500 510 520 530 540
AITISTNMAG RGTDIKVSDE IRELGGLYVI GTERHESRRI DNQLRGRTGR QGDPGESRFF
550 560 570 580 590 600
TSLEDALFKR FATDRFEKAS QKLEEEFYDS RFFSKMLDRT QKKVEGLNFD IRKNLMDYDH
610 620 630 640 650 660
VLSLQRELIY KQRDQILLKT NNLNIINNMI DDYVETEILN FKNNDNTSLV DANKIVAFLN
670 680 690 700 710 720
EKILKFSYFT PATFANMPIL LAIDKAISII KKVVDVKCKI LEKINGLNVI DEILLVNLDQ
730 740 750 760 770 780
KWTTHIDKMT KLREGVNLRS LEQRSPLNIY IEDGNNLFER MKINVVTDTI TSICNLSLPN
790 800 810 820 830 840
EMIEITNALD EFVNSEEFKK KNYGNQREIE QNFNSALSFS GSATSEFDNF IESELENTLI
850 860 870 880 890 900
EETPEEYVEV EEYIPQQTEP EVVETETTPY GFEIPKYDTS GTDKYELNNG SSEVNILENE
910 920 930 940 950 960
SDIFENSFSQ IQNTFNTEEL DPQETPHTAK ADDQFVFESA NLEDDIEEIE NVSNIDKAPE
970 980 990 1000 1010 1020
IQQPLSEEEI QKILDMPAFK DDEKPLTIGN YLDNILDSMD IDYDQDKEIT QQLEPSSNEQ
1030 1040 1050 1060 1070 1080
EVTANIPEQN QLDITTSDID NEIELLDESE RESIKEEIQK SISFDLSNDP DFIEYRNSVF
1090 1100 1110 1120 1130 1140
VNKNNGIDYS DYKKLNEDES DDDIKAFYKL PKVDKKEPGT LFGGNLLKKT PFNFKNKNEL
1150 1160 1170 1180 1190 1200
DNEKIKSTNL FREENQASEQ ELNTLLQLDD EKDRLEKINQ LLNKEDPEVL ERKELERQVE
1210 1220 1230 1240 1250 1260
FETPVYYLED IPEGESLDNF KAMDNPHEEQ SFEDNLVDEE NQQLEFEEAL DEVIDDGQFN
1270 1280 1290 1300 1310 1320
DEVEAAELSE EVLEEVINPN PEELSEEDKW LITKKEHEKF MEKYLGDVKE LTSENPEVVT
1330 1340 1350 1360 1370 1380
ALLQEKNKNL KDVEIIENNE ELENTNEEEP NINSQDSFLN NIKIIKTVDK ESEDETEIIQ
1390 1400
EINQPAEIHN LQKDILDYLK ENNKK