Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q8EUR3

Entry ID Method Resolution Chain Position Source
AF-Q8EUR3-F1 Predicted AlphaFoldDB

No variants for Q8EUR3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8EUR3

No associated diseases with Q8EUR3

8 regional properties for Q8EUR3

Type Name Position InterPro Accession
domain RNA polymerase, alpha subunit 351 - 517 IPR000722
domain RNA polymerase, N-terminal 242 - 545 IPR006592
domain RNA polymerase Rpb1, domain 3 520 - 691 IPR007066
domain RNA polymerase Rpb1, domain 1 12 - 349 IPR007080
domain RNA polymerase Rpb1, domain 5 829 - 1385 IPR007081
domain RNA polymerase Rpb1, domain 4 717 - 822 IPR007083
domain DNA-directed RNA polymerase III subunit RPC1, N-terminal 22 - 879 IPR035697
domain DNA-directed RNA polymerase III subunit RPC1, C-terminal 1091 - 1430 IPR035698

Functions

Description
EC Number 7.6.2.11 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell membrane ; Peripheral membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
ABC-type polyamine transporter activity Catalysis of the reaction: ATP + H2O + polyamine(out) = ADP + phosphate + polyamine(in).
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKTKDNEVIN SESEFSEKDV PNFIEIKKIN KTYPDGYVAV KNINFEIKKG EFVTILGPSG
70 80 90 100 110 120
CGKTTILKMI GGFELPTSGK ILVNKIDIKD LPIQRRPTAT VFQDYALFPN MNVEKNIAYG
130 140 150 160 170 180
LTEIRKPIEN VSADYQKESE KYFNDCLKKS KSKIKDIERK RDGFLKDIQK LENKINNSKI
190 200 210 220 230 240
LSEVNTMTEE EYEEKIETLE KEYFEKNKKE LHKSIPVKVK FIEFINNTLS FFRINKNIDF
250 260 270 280 290 300
KANETDELVQ TYLKYEKAYR VNLITKQEID YLNHKAADLD YWVSYWQNYP YQEKEWFDKK
310 320 330 340 350 360
KLTRKLTKQE IKEEVQQIIK IIGLEGKEKK WPSDLSGGMQ QRVALARALV IKPETLLLDE
370 380 390 400 410 420
PLSALDAKVR AQMQQELKNL HKKFGITFIL VTHDQEEALT LSDKIIVMSQ GKIQQIGTPN
430 440 450 460 470 480
EIYDLPANNW VANFIGKANI LNATYLKGNK IKLFDNVLNA DSRYKDKFKE NEEVNVMIRP
490 500 510 520 530 540
EDFDVVGKDK GKIKVTVLET TYKGLMWELI CEFEGVLLTL EAVNKVNLEQ EIYLTWDDED
550 560 570 580 590
MHIMKKDDEN DTYTDESSEF LALTKNAFKK KIKEIKSKKN KNKVNGKKGD KNDN