Q8EPH7
Gene name |
rnhC |
Protein name |
Ribonuclease HIII |
Names |
RNase HIII |
Species |
Oceanobacillus iheyensis (strain DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954 / HTE831) |
KEGG Pathway |
oih:OB2128 |
EC number |
3.1.26.4: Endoribonucleases producing 5'-phosphomonoesters |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q8EPH7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q8EPH7-F1 | Predicted | AlphaFoldDB |
No variants for Q8EPH7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q8EPH7 | |||||
No associated diseases with Q8EPH7
1 regional properties for Q8EPH7
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Ribonuclease H domain | 1 - 141 | IPR002156 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.1.26.4 | Endoribonucleases producing 5'-phosphomonoesters |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| magnesium ion binding | Binding to a magnesium (Mg) ion. |
| RNA binding | Binding to an RNA molecule or a portion thereof. |
| RNA-DNA hybrid ribonuclease activity | Catalysis of the endonucleolytic cleavage of RNA in RNA-DNA hybrids to 5'-phosphomonoesters. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| RNA catabolic process | The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSQQVIVTTK | EQIQKMKKYY | LSQLTSTPQG | AIFRAKTNNA | VITAYQSGKV | LFQGSAPESE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ASKWGNVPLN | DKKKHSLEQK | HSYSPQAELF | TDNHIGSDEA | GTGDYFGPIT | VAALFATKEQ |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QLKLKQIGVR | DSKHLNDTKI | KQIAKEIAHL | QIPYSLLLLP | NGKYNKLQAK | GWSQGKMKAM |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LHHHAIDKLL | QKIDVRSLKG | IVIDQFCQPP | VYKKYLQSEK | KTLHPNTTFI | TKAESHSISV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| AAASILARAR | FVNAMDELSE | EAKMELPKGA | SAKVDQTAAR | LIRSKGFEEL | DKYAKTHFAN |
| TQKAQKLL |