Q8EJM6

PR
Gene name
pdeB (SO_0437)
Protein name
Cyclic di-GMP phosphodiesterase PdeB
Names
Phosphodiesterase biofilm protein
Species
Shewanella oneidensis (strain MR-1)
KEGG Pathway
son:SO_0437
EC number
3.1.4.52: Phosphoric diester hydrolases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

41-113 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8EJM6

Entry ID Method Resolution Chain Position Source
AF-Q8EJM6-F1 Predicted AlphaFoldDB

No variants for Q8EJM6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8EJM6

No associated diseases with Q8EJM6

5 regional properties for Q8EJM6

Type Name Position InterPro Accession
domain 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain 542 - 866 IPR002073
domain GAF domain 175 - 334 IPR003018-1
domain GAF domain 356 - 522 IPR003018-2
domain HD/PDEase domain 617 - 793 IPR003607
conserved_site 3'5'-cyclic nucleotide phosphodiesterase, conserved site 658 - 669 IPR023174

Functions

Description
EC Number 3.1.4.52 Phosphoric diester hydrolases
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
cyclic-guanylate-specific phosphodiesterase activity Catalysis of the reaction: cyclic di-3',5'-guanylate + H(2)O = 5'-phosphoguanylyl(3'->5')guanosine + H(+).

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRIGNKILVF IVGFCLPAVV LVSYCLGVWF DHRVELLRQD NVRHELANIQ QQFRIDVDRL
70 80 90 100 110 120
GFLTNIYASP LSHLDSEQLK SLESSWLESS MSGNLSWFIL RDGNLQNVFQ NEQPIAEANR
130 140 150 160 170 180
QEIAKAITTQ AKPEFASAYL IGDKGYVVTA VASHLGEYVL LVRQLTERDL LEYAQTSLVA
190 200 210 220 230 240
RVSMSNVVTA HHSSHSSSVA LPSLISQQPI YLHVEFSDDP FRDVKLSLDW VSLAVILLGI
250 260 270 280 290 300
LIVALGYVWL RACLLQPFKS LMQQLALVDP MASVYRPVTS EGNEELSVLA NRVNSLLARI
310 320 330 340 350 360
YQQKERGKIT LESIAEAVIL TDIEAKVIYM NPKAETLLEV ASSNAVGESL ASLLKAGEQL
370 380 390 400 410 420
NQAVFHCIRL GETMPQVAKI KLLTTMPRII ERSISNVLNH EKEIVGTVVV LRDITQEELL
430 440 450 460 470 480
KHQLQKRANF DGITGLLNRQ AFEEQLPEFA SQARSLAVCY LDLEQFKLIN DSCGHTAGDR
490 500 510 520 530 540
MLAMVARAIQ SCLGPQELLA RIGGDEFGLV ICDRTALAVA QLLKQIIAQV SLQVLHDKNC
550 560 570 580 590 600
NYKVGLSIGV AFGRAPYINA QELLKDADIA CIAAKAKGTN QIHIYDDKDK ELTYQRNAPK
610 620 630 640 650 660
WAVRIAQAIE ENELLLYYQP IRGLGASSKR QRMEVLLRIQ EPCGRILAPA QFIAAAERFK
670 680 690 700 710 720
LMPEIDKEVI RKAFLWLSLN SQLWQDHCIS INLSGNSLGA EGMVEYIAKQ QQIFDIPSQC
730 740 750 760 770 780
VCFEITETTA IQNRHRGMEM LRQLRKLGFS FALDDFGSGF ASYGYLRELP VDYVKIDGCF
790 800 810 820 830 840
VKNLAVNAKD YAIVKSIQDV CRVMGIETVA EFVENQEIID RLQTIGINYA QGYAIGRPQP
850
LASYCEQFET RLAQRA