Q8EGH8

PR
Gene name
glnD
Protein name
Bifunctional uridylyltransferase/uridylyl-removing enzyme
Names
UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein
Species
Shewanella oneidensis (strain MR-1)
KEGG Pathway
son:SO_1626
EC number
2.7.7.59: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

568-638 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8EGH8

Entry ID Method Resolution Chain Position Source
AF-Q8EGH8-F1 Predicted AlphaFoldDB

No variants for Q8EGH8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8EGH8

No associated diseases with Q8EGH8

6 regional properties for Q8EGH8

Type Name Position InterPro Accession
domain ACT domain 676 - 756 IPR002912-1
domain ACT domain 784 - 861 IPR002912-2
domain Polymerase, nucleotidyl transferase domain 52 - 98 IPR002934
domain HD/PDEase domain 430 - 577 IPR003607
domain HD domain 434 - 566 IPR006674
domain PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase 163 - 299 IPR013546

Functions

Description
EC Number 2.7.7.59 Nucleotidyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
[protein-PII] uridylyltransferase activity Catalysis of the reaction: UTP + (protein-PII) = diphosphate + uridylyl-(protein-PII).
phosphoric diester hydrolase activity Catalysis of the hydrolysis of a phosphodiester to give a phosphomonoester and a free hydroxyl group.

2 GO annotations of biological process

Name Definition
nitrogen compound metabolic process The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen.
regulation of nitrogen utilization Any process that modulates the frequency, rate or extent of nitrogen utilization.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNTALLAKQS LIEQNQTLLA RFKAKTPIEE LVTQRCQFVD SLVKQAWQQH GLDQYPIALI
70 80 90 100 110 120
AVGGYGRGEL HPHSDVDLLF LFEGELSKAA ETTLSEFIAF LWDANLEIGH SVRTLDDTLR
130 140 150 160 170 180
LGRDDITIAT NLLEARLLTG PETLFDQLYD AIRQSDFWTS SNFFIAKRDE QTARHAKASA
190 200 210 220 230 240
FDLEPNIKSC PGGLRDIQTI AWVAMRHFGA SRLEELVEYE FLEPAELEEL LECQHFLWKL
250 260 270 280 290 300
RFALHMAVGR DENRLLFDVQ RQVAELMGYE DATQLAVEQM MKRYYRTVRR VMELNEMLLQ
310 320 330 340 350 360
LFKRATLGHT KALEIQAIDD NYQRRGAFIE ALSDDLFDSG EEIVRLFVHI AKNSNIKGIY
370 380 390 400 410 420
APTLRSLRRA RRAQLQPLQE NPLCRQAFME ILKHPRGIAA LSLMHKHGVL SAYLPAWRNI
430 440 450 460 470 480
EGQMQFDLFH AYTVDEHTHR LLLNIERFSQ PEQKEEFPLG SVLINQLPKK GLLVLGAIFH
490 500 510 520 530 540
DIAKGRGGDH SKLGSSDALA FCKLHGLNDH DGRLVAWLVE NHLVMSVTAQ RRDISDPDVV
550 560 570 580 590 600
ADFASKVRDA VHLSYLYCLT VADICATNEK TWNNWKGSLL RDLYFSTQRV LARGKEKPVD
610 620 630 640 650 660
IRARVREYQA KAKKELLRRG IKEKDLDTLW QRFKADYFLR HQPNQVAWHA EAILKHKQVD
670 680 690 700 710 720
EPLVLVSKHT TRGGTELFVY CQDRPKLFAT VMAVLDNKNI NVHDANIMTS KDNYALDTFV
730 740 750 760 770 780
ILEQDGEPVS QLSRIQSIRK ALEKALASDN PKLPRFRKLS RKMKPFNVPT QVSFLESNRH
790 800 810 820 830 840
GTSMMELIAL DTPGLLAKVG DIFYRCNTTL LSAKITTIGE RAEDFFILQT NDGLQLNETQ
850 860
EHTLKEALIS ALSAINTEST N