Q8EFF7

PR
Gene name
htpG
Protein name
Chaperone protein HtpG
Names
Heat shock protein HtpG, High temperature protein G
Species
Shewanella oneidensis (strain MR-1)
KEGG Pathway
son:SO_2016
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

468-621 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8EFF7

Entry ID Method Resolution Chain Position Source
AF-Q8EFF7-F1 Predicted AlphaFoldDB

No variants for Q8EFF7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8EFF7

No associated diseases with Q8EFF7

3 regional properties for Q8EFF7

Type Name Position InterPro Accession
domain Histidine kinase/HSP90-like ATPase 26 - 183 IPR003594
conserved_site Heat shock protein Hsp90, conserved site 24 - 33 IPR019805
domain Heat shock protein Hsp90, N-terminal 4 - 207 IPR020575

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
ATP-dependent protein folding chaperone Binding to a protein or a protein-containing complex to assist the protein folding process, driven by ATP hydrolysis.
unfolded protein binding Binding to an unfolded protein.

3 GO annotations of biological process

Name Definition
cellular response to DNA damage stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
protein folding The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.
response to heat Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSQQETHGFQ TEVKQLLHLM IHSLYSNKEI FLRELVSNAA DAADKLRYLA LTNDALYEGD
70 80 90 100 110 120
GELRVRISAD KEKGTVTIED NGVGMTRDGV IEHLGTIAKS GTAEFFKNLS GEASKDSQLI
130 140 150 160 170 180
GQFGVGFYSA FIVAKKVTVR TRAAGHKANE AVLWESEGEG SFTVETITKA TRGTEITLHL
190 200 210 220 230 240
RDDEKEFADD WRLRSIITKY SDHISIPVEM WQEGTPERDG PDGEKIPATE GYWKAMNKAT
250 260 270 280 290 300
ALWMRNKSEI TDEEYQEFYK HISHDYTDAL LWSHNRVEGK QEYTNLLYIP SKAPWDLWNR
310 320 330 340 350 360
DRKHGLKLFV QRVFIMDDAE QFMPSYLRFV QGLIDSNDLP LNVSREILQD NHITKAMRTG
370 380 390 400 410 420
ITKRVLGMLE KLAKDDAEKY QQFWAEFGQV LKEGPAEDFA NRERIAGLLR FASTHTGSAA
430 440 450 460 470 480
PTVSLDDYIS RMKEGQTKIY YIVADSHEAA ANSPHLELLR KKGIEVLLMS ERIDEWLINH
490 500 510 520 530 540
LTEYKEKQLH SVTRGELELG ELEDAAEKEA QEKLAEESAP LIERIKAALG ASVADVKVTS
550 560 570 580 590 600
RLTDTPACVV TGEGEMSTQM IKLMQAAGQP VPEVKPTFEV NPAHPLVSRL NDLQDEAAFA
610 620 630
DWSNLLLQQA QLSEKGSLAD PSAFIKLMNQ MLLANLK