Q8EEN5

PR
Gene name
nadA
Protein name
Quinolinate synthase
Names
Species
Shewanella oneidensis (strain MR-1)
KEGG Pathway
son:SO_2342
EC number
2.5.1.72: Transferring alkyl or aryl groups, other than methyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-51 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8EEN5

Entry ID Method Resolution Chain Position Source
AF-Q8EEN5-F1 Predicted AlphaFoldDB

No variants for Q8EEN5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8EEN5

No associated diseases with Q8EEN5

No regional properties for Q8EEN5

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q8EEN5

Functions

Description
EC Number 2.5.1.72 Transferring alkyl or aryl groups, other than methyl groups
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

3 GO annotations of molecular function

Name Definition
4 iron, 4 sulfur cluster binding Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
metal ion binding Binding to a metal ion.
quinolinate synthetase A activity Catalysis of the reaction: iminoaspartate + dihydroxy-acetone-phosphate = quinolinate + 2 H2O + phosphate.

1 GO annotations of biological process

Name Definition
'de novo' NAD biosynthetic process from aspartate The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of aspartate from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSSSLFAPTI ETIDYPFPPK PVPLSDAQKA DYKARIKQLL IEKDAVLVAH YYTDPEIQAL
70 80 90 100 110 120
AEETGGCVSD SLEMARFGRD HPAKTLIVAG VKFMGETAKI LSPEKTILMP TLEATCSLDL
130 140 150 160 170 180
GCPIDKFSAF CDAHPDHTVV VYANTSAAVK ARADWVVTSS IALEIVEHLD SEGKKIIWGP
190 200 210 220 230 240
DRHLGSYIAK QTGAEMLMWQ GDCIVHDEFK ANALRDLKSV YPDAAILVHP ESPASVVAMA
250 260 270 280 290 300
DAVGSTSQLI KAAQTMPNER FIVATDRGIF YKMQQAAPGK TLIEAPTGGN GATCKSCAHC
310 320 330 340 350
PWMAMNGLKA IEASLSNSDK TTHEIFVDED LRVKALIPLT RMLDFAKTLN MKVKGNA