Q8EBC3

PR
Gene name
cysA1
Protein name
Sulfate/thiosulfate import ATP-binding protein CysA 1
Names
Sulfate-transporting ATPase 1
Species
Shewanella oneidensis (strain MR-1)
KEGG Pathway
son:SO_3602
EC number
7.3.2.3: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

288-376 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q8EBC3

Entry ID Method Resolution Chain Position Source
AF-Q8EBC3-F1 Predicted AlphaFoldDB

No variants for Q8EBC3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q8EBC3

No associated diseases with Q8EBC3

5 regional properties for Q8EBC3

Type Name Position InterPro Accession
domain ABC transporter-like, ATP-binding domain 3 - 237 IPR003439
domain AAA+ ATPase domain 27 - 214 IPR003593
domain Sulphate transport system permease protein 1 1 - 242 IPR005666
conserved_site ABC transporter-like, conserved site 137 - 151 IPR017871
domain TOBE-like domain 287 - 346 IPR024765

Functions

Description
EC Number 7.3.2.3 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell inner membrane ; Peripheral membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
ATP-binding cassette (ABC) transporter complex A complex for the transport of metabolites into and out of the cell, typically comprised of four domains; two membrane-associated domains and two ATP-binding domains at the intracellular face of the membrane, that form a central pore through the plasma membrane. Each of the four core domains may be encoded as a separate polypeptide or the domains can be fused in any one of a number of ways into multidomain polypeptides. In Bacteria and Archaebacteria, ABC transporters also include substrate binding proteins to bind substrate external to the cytoplasm and deliver it to the transporter.

3 GO annotations of molecular function

Name Definition
ABC-type sulfate transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + sulfate(out) = ADP + phosphate + sulfate(in).
ABC-type thiosulfate transporter activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + thiosulfate(out) = ADP + phosphate + thiosulfate(in).
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

1 GO annotations of biological process

Name Definition
sulfate transport The directed movement of sulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSIRLTNISK KFGQFQALSP LNLDIQEGEM IGLLGPSGSG KTTLLRIIAG LEGADSGHIH
70 80 90 100 110 120
FGNRDVTQVH VRDRRVGFVF QNYALFRHMT VADNVAFGLE VIPKKQRPSA AEIQKRVSHL
130 140 150 160 170 180
LEMVQLGHLA QRYPEQLSGG QKQRIALARA LATQPEVLLL DEPFGALDAK VRKELRRWLR
190 200 210 220 230 240
SLHDELKFTS VFVTHDQDEA LELSDRVVVM SNGNIEQVNT PIELYAQPNS RFVFDFLGNV
250 260 270 280 290 300
NRFEANWQQN RWTNGDAFIV PPEQTPLQQN GALYVRSHEL ALADKPNSQA HIPFTIVAIT
310 320 330 340 350 360
PIGAEVRVEL APIGWQSEEL WEAKFTHHHL QELGLQKGSV VYATPRTGYF FGKQGDGSPI
370
RQSWPFLPPG SLAFDI